- Global Maternal and Child Health
- Malaria Research and Control
- Mosquito-borne diseases and control
- Adolescent Sexual and Reproductive Health
- Viral Infections and Outbreaks Research
- Global Public Health Policies and Epidemiology
- HIV/AIDS Research and Interventions
- Vaccine Coverage and Hesitancy
- Reproductive Health and Contraception
- Healthcare Systems and Reforms
- Parasitic Diseases Research and Treatment
- Viral Infections and Vectors
- Child Nutrition and Water Access
- Hepatitis B Virus Studies
- Data-Driven Disease Surveillance
- Emergency and Acute Care Studies
- Parasites and Host Interactions
- Injury Epidemiology and Prevention
- Rabies epidemiology and control
- Menstrual Health and Disorders
- Ethics in Clinical Research
- Global Health and Epidemiology
- Demographic Trends and Gender Preferences
- Respiratory Support and Mechanisms
- Global Health Workforce Issues
London School of Hygiene & Tropical Medicine
2013-2025
University of Health and Allied Sciences
2016-2025
University of London
2018-2023
Sierra Leone Urban Research Centre
2021-2023
Mwanza Intervention Trials Unit
2022
National Institute for Medical Research
2022
Kintampo Health Research Centre
2010-2021
Ghana Health Service
2006-2021
LDS Business College
2015-2020
University of North Carolina at Chapel Hill
2020
<b>Objectives</b> To examine the impact of use rapid diagnostic tests for malaria on prescribing antimicrobials, specifically antibiotics, acute febrile illness in Africa and Asia. <b>Design</b> Analysis<b></b>of nine preselected linked codesigned observational randomised studies (eight cluster or individually trials one study). <b>Setting</b> Public private healthcare settings, 2007-13, Afghanistan, Cameroon, Ghana, Nigeria, Tanzania, Uganda. <b>Participants</b> 522 480 children adults with...
Abstract Background Uptake of postpartum family planning (PPFP) remains low in sub-Saharan Africa and very little is known about how pregnant women arrive at their decisions to adopt PPFP. This information needed guide the development interventions promote Methods We conducted a survey among attending antenatal clinics rural district Ghana. used univariate multivariate logistic regression analysis explore knowledge various (FP) methods, past experience with use acceptability PPFP male...
Unintended pregnancies may carry serious consequences for women and their families, including the possibility of unsafe abortion, delayed prenatal care, poor maternal mental health child outcomes. Although between 1993 2008, unintended births decreased from 42% to 37% in Ghana, rate decline is low, whilst levels are still very high. This raises need understand factors associated with pregnancies, especially among rural settings where rates risks highest help improve health. We collected data...
Abstract Background Malaria rapid diagnostic tests (mRDTs) that target histidine-rich protein 2 (HRP2) are important tools for Plasmodium falciparum diagnosis. Parasites with pfhrp2/3 gene deletions threaten the use of these mRDTs and have been reported in Africa, Asia, South America. We studied blood samples from 3 African countries to determine if were present. Methods analyzed 911 dried spots Ghana (n = 165), Tanzania 176), Uganda 570). infection was confirmed by 18S rDNA polymerase chain...
Abstract This study reports the results of a cross-sectional questionnaire survey undertaken in Kassena-Nankana district Ghana to assess perception and attitude 270 antenatal clinic attendants towards voluntary counseling HIV testing. It was found that although 92.6% (95% CI 88.8–95.4) respondents indicated willingness get tested, only 51% 45.0–57.2) considered testing for pregnant women be useful. Most (93.6%) they would like their husbands (partners) know result test 52.2% willing...
Abortion continues to be used as a method of family planning by many women. The complications unsafe abortions are major contributor maternal mortality in sub-Saharan Africa, including Ghana. This study explored the influence socio-demographic characteristics on 156 communities within Kintampo Health and Demographic Surveillance System (KHDSS) area located middle part Ghana.A survey Sexual Reproductive among representative sample females aged 15-49 years was conducted 2011. They were asked...
Since 2010, the World Health Organization has been recommending that all suspected cases of malaria be confirmed with parasite-based diagnosis before treatment. These guidelines represent a paradigm shift away from presumptive antimalarial treatment fever. Malaria rapid diagnostic tests (mRDTs) are central to implementing this policy, intended target artemisinin-based combination therapies (ACT) patients and improve management nonmalarial fevers. The ACT Consortium conducted ten linked...
BackgroundIn low-income and middle-income countries, invasive mechanical ventilation is often not available for children at risk of death from respiratory failure. We aimed to determine if continuous positive airway pressure (CPAP), a form non-invasive ventilation, decreases all-cause mortality in with undifferentiated distress Ghana.MethodsThis open-label, cluster, crossover trial was done two Ghanaian non-tertiary hospitals where routinely available. Eligible participants were aged 1 month...
Introduction: Fresh vegetables are an important source of vital nutrients. Poor farming practices and improper washing put consumers at risk parasitic infections. This study explored the presence contamination commonly-consumed procured from two markets in Ghana. It also decontamination effects with different concentrations saline solution.Method: Vegetables were major open Koforidua, thoroughly washed twice using 0.0%, 0.45%, 0.9%, 1.5% solutions. The deposits examined under light...
To describe the trend and causes of neonatal deaths in a rural district northern Ghana.Descriptive analysis data collected from Navrongo Demographic Surveillance System verbal autopsies conducted on all 1995-2002.Of 1118 recorded 1068 (95.5%) could be analysed. Only 13.2% occurred at health facility; 62.7% early period, with prematurity (38%) birth injuries (19%) as leading causes. Infectious (66%) were major contributors to late deaths. Infanticide accounted for 4.9% The cause-specific...
Rational: Female genital mutilation (FGM) is prevalent in northern Ghana, as the practice seen a passage rite to women adulthood and thus undertaken just before marriage. Objectives: We determined changes trend of FGM deliveries at Navrongo War Memo-rial hospital, compared outcomes status.Design: Retrospective extraction analysis delivery data hospital from 1st January 1996 31st December 2003. Results: Of 5071 deliveries, about 29% (1466/5071) were associated with FGM. The high-est...
WHO now recommends test-based management of malaria across all transmission settings. The accuracy rapid diagnostic test (RDT) and the outcome treatment based on result tests will influence acceptability adherence to new guidelines.We conducted a study at Kintampo hospital in rural Ghana evaluate performance CareStart, HRP-2 RDT, using microscopy as reference. We applied IMCI guidelines, restricted ACT RDT-positive children followed-up both (malaria) RDT-negative (non-malaria) cases over 28...
White blood cells count (WBCc) is a bedrock in the estimation of malaria parasite density field trials, interventions and patient management. are indirectly relatively used microscopy to estimate infections. Due frequent lack facilities some malaria-endemic countries, order quantify WBCc patients, an assumed 8.0 X 10(9)/L has been set by World Health Organization help estimating densities. This comparative analysis study, Central Ghana, compiled laboratory data 5,902 Plasmodium falciparum...
We developed a test battery for use among children in Bangladesh, Ghana, and Tanzania, assessing general intelligence, executive functioning, school achievement. The instruments were drawn from previously published materials tests. adapted translated systematic way to meet the needs of three assessment contexts. administered by total 43 trained assessors 786 Tanzania with mean age about 13 years (range: 7-18 years). provides psychometrically solid basis evaluating intervention studies...
Objectives The overuse of antimalarial drugs is widespread. Effective methods to improve prescribing practice remain unclear. We evaluated the impact 10 interventions that introduced rapid diagnostic tests for malaria (mRDTs) on use and adherence results in different contexts. Design A comparative case study approach, analysing variation outcomes across settings. Setting Studies from ACT Consortium evaluating mRDTs with a range supporting 6 endemic countries. Providers were governmental or...
Very little is known about multimorbidity and chronic diseases in low middle income countries, particularly Sub-Saharan Africa, more information needed to guide the process of adapting health systems these countries respond adequately increasing burden diseases. We conducted a hospital-based survey an urban setting Ghana determine prevalence its associated risk factors among adult patients presenting inner city clinic. Between May June 2012, we interviewed (aged 18 years above) attending...
(1) Background: Menstruation, experienced by 1.8 billion girls and women globally, is often misunderstood surrounded taboos misconceptions, particularly in low-income countries like Ghana. This study explores the Ghanaian socio-cultural representation of menstruation cultural experiences young during menarche. (2) Methods: qualitative exploratory was conducted five Senior High Schools Ghana's Volta Region, using purposive convenience sampling. Fifteen Focus Group Discussions (FGDs) were...
Cardiovascular disease (CVD) risk factors lead to morbidity and mortality among adults globally. In Ghana, there is a lack of coordinated efforts at all levels healthcare service prevent cardiovascular (CVD). This study assessed residents resource-limited rural settings. descriptive cross-sectional design the first phase two-year community-level aimed implementing an intervention reduce CVD in community Ghana. The population included 379 people living Avenui community. We conducted nurse-led...
During the 2014-2016 Ebola epidemic in West Africa and outbreaks between 2018 2020 Democratic Republic of Congo, vaccines other tools for prevention treatment had to be taken through trials exceptional circumstances using accelerated processes. We interviewed members ethics committees, health authorities, professionals, political authorities Congo 2021 held a workshop with committee regulatory from Sierra Leone Guinea 2022 order document their experiences reviewing, approving, regulating...