- Botulinum Toxin and Related Neurological Disorders
- Neurological disorders and treatments
- Advanced Control Systems Optimization
- Complex Network Analysis Techniques
- Parkinson's Disease Mechanisms and Treatments
- Neural Networks and Applications
- Gene Regulatory Network Analysis
- Ophthalmology and Eye Disorders
- Smart Grid Energy Management
- Fault Detection and Control Systems
- Building Energy and Comfort Optimization
- Genetic Neurodegenerative Diseases
- Artificial Immune Systems Applications
- Cancer Treatment and Pharmacology
- Molecular Communication and Nanonetworks
- Fuzzy Logic and Control Systems
- Industrial Technology and Control Systems
- Vestibular and auditory disorders
- Distributed systems and fault tolerance
- Petri Nets in System Modeling
Case Western Reserve University
2015-2025
Louis Stokes Cleveland VA Medical Center
2023-2024
Cervical dystonia (CD) is an intricate neurological condition with motor and nonmotor symptoms. These include disruptions in visual perception, self-orientation, working memory, vestibular functions. However, the specific impact of CD on perceiving self-motion direction, especially isolated or stimuli, remains largely unexplored.This study aimed to examine effects linear motion hypothesizing impaired heading discrimination both tasks, that such deficits correlate disease severity.We employed...
This paper uses a two-level model predictive control-based approach for the coordinated control and energy management of an integrated system that includes photovoltaic (PV) generation, storage, building loads. Novel features proposed local controller include (1) ability to simultaneously manage loads storage achieve different operational objectives such as efficiency, economic cost demand response grid optimization through design specific power trajectory tracking performance functionals,...
This article presents details of the installation and testing a two-level control system for building with rooftop photovoltaic (PV) energy storage (ES). The proposed interacts system-level controller to manage real reactive power consumption PV ramp rate through dynamic adjustment loads (BLs) (slower time-scale) in coordination charging discharging battery ES (ESS) (faster time-scale). A unique contribution compared other techniques literature is that real-time trajectories by controller,...
Objective: Dystonias, characterized by excessive muscle contractions resulting in involuntary postures and movements, impact 3 million people globally, making them the third most common movement disorder. Often accompanied tremors, dystonias have epidemiological links non-motor features shared with isolated tremor, such as essential tremor. Both dystonia tremor present balance dysfunction abnormal potentially linked to cerebellar function. This study explores perception of one’s own linear...
Introduction: This study explores the effects of botulinum neurotoxin (BoNT) on relationship between dystonia and tremor, specifically focusing cervical (CD) its connection to head tremor. Methods: Fourteen CD patients were recruited; eight (57%) with clinically observable oscillations included in further analysis. A high-resolution magnetic search coil system precisely measured movements, addressing two questions: 1) BoNT’s movement amplitude, frequency, regularity, 2) influence position...
To examine visual and vestibular spatial perception skills in patients with cervical dystonia.
Dystonias, characterized by excessive muscle contractions resulting in involuntary postures and movements, impact 3 million people globally, making them the third most common movement disorder. Often accompanied tremors, dystonias have epidemiological links non-motor features shared with isolated tremor, such as essential tremor. Both dystonia tremor present balance dysfunction abnormal potentially linked to cerebellar function. This study explores perception of one’s own linear movement,...
Systems can be viewed as collections of interconnected elements that communicate with one another through physical phenomena. The principal focus this work is the development distributed algorithms for eliciting intrinsic communication topology within a system and employ them condition monitoring systems. proposed approach in paper provides operators graphs instead tables or correlation matrices to identify presence fault request appropriate actions mitigate it. Specifically, considers...
We propose an information-theoretic framework for modeling complex systems as a communication network where physical devices can be organized into subsystems and are communicating through information channel governed by the dynamics of system.