A5060418610- Gold and Silver Nanoparticles Synthesis and Applications
- Analytical chemistry methods development
- Electrochemical Analysis and Applications
- Advanced NMR Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Nanocluster Synthesis and Applications
- Barrier Structure and Function Studies
- Ion-surface interactions and analysis
- Neurological Disease Mechanisms and Treatments
- Advanced biosensing and bioanalysis techniques
- Drug-Induced Hepatotoxicity and Protection
- Advanced MRI Techniques and Applications
- Electron Spin Resonance Studies
- Catalytic Processes in Materials Science
- Silymarin and Mushroom Poisoning
- Hedgehog Signaling Pathway Studies
- Chemical Reactions and Isotopes
- Advanced Nanomaterials in Catalysis
- Nanoparticles: synthesis and applications
- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Mesoporous Materials and Catalysis
- Hungarian Social, Economic and Educational Studies
- Mercury impact and mitigation studies
- Ionic liquids properties and applications
Gedeon Richter (Hungary)
2023-2024
University of Copenhagen
2018-2022
University of Szeged
2015-2020
Blood–brain barrier (BBB) models derived from human stem cells are powerful tools to improve our understanding of cerebrovascular diseases and facilitate drug development for the brain. Yet providing cell–derived endothelial with right signaling cues acquire BBB characteristics while also retaining their vascular identity remains challenging. Here, we show that simultaneous activation cyclic AMP Wnt/β-catenin inhibition TGF-β pathway in robustly induce properties vitro. To target this...
The spectral interference effects occurring in SP-ICP-MS are discussed<italic>via</italic>the examples of the measurement Fe<sub>2</sub>O<sub>3</sub>, Cr<sub>2</sub>O<sub>3</sub>, and ZnO particles.
By combining normal and high temporal resolution spICP-MS measurements, the accurate dimensional analysis of nanorods is possible.
Fluorescent, DNA-stabilized silver nanoclusters (DNA-AgNCs) are applied in a range of applications within nanoscience and nanotechnology. However, their diverse optical properties, mechanism formation, aspects composition remain unexplored, making the rational design nanocluster probes challenging. Herein, synthetic procedure is described for obtaining high yield emissive DNA-AgNCs with C-loop hairpin DNA sequence, subsequent purification by size-exclusion chromatography (SEC). Through...
The accurate load concentration of ultra small nanoparticles in a Pt/SiO<sub>2</sub> nanocomposite is determined by the novel spICP-MS analytical method.
6.6 nm Pt nanoparticles with narrow size distribution were anchored on mostly identical, amorphous silica supports (SBA-15, MCF-17, foam) and tested in ethanol decomposition reactions at <300 °C. The reaction the Pt/SBA-15 was ∼2 times faster (0.073 molecules·site–1·s–1) compared Pt/MCF-17 (0.042 Pt/SF (0.040 300 In case of Pt/SF, selectivity toward acetaldehyde higher catalysts. Pt/SBA-15, methane to ratio ∼4 catalyst. ethene ∼1.5 Pt/SF. Small-angle X-ray scattering (SAXS) studies showed...
NMR spectra of Mg2+ ions in ionic liquids were recorded using a highly sensitive variant spectroscopy known as β-NMR. The β-NMR MgCl2 EMIM-Ac and EMIM-DCA compare favourably with conventional NMR, exhibit linewidths ∼3 ppm, allowing for discrimination species oxygen nitrogen coordination.
Efficient and selective Hg<sup>2+</sup>binding of a hexapeptide containing two cysteine residues is demonstrated both in solution immobilized forms.
Abstract Fluorescent, DNA‐stabilized silver nanoclusters (DNA‐AgNCs) are applied in a range of applications within nanoscience and nanotechnology. However, their diverse optical properties, mechanism formation, aspects composition remain unexplored, making the rational design nanocluster probes challenging. Herein, synthetic procedure is described for obtaining high yield emissive DNA‐AgNCs with C‐loop hairpin DNA sequence, subsequent purification by size‐exclusion chromatography (SEC)....
Introduction and aims - Particles of titanium dioxide (TiO2) with typical size below 100 nm have gained a broad range application by now, partly involving direct human exposure. Their known properties high specific surface, mobility within the organism, induction oxidative stress, release inflammation mediators etc. raise possibility nervous system damage but available data regarding this are scarce contradictory. Based on that, experiences other metal oxide nanoparticles, aim present study...
Inhalation of manganese-containing metal fumes at workplaces can cause central nervous damage including a Parkinson-like syndrome. Oxidative stress is likely to be involved in the pathomechanism, due presence nano-sized oxide particles with high biological and chemical activity. system could prevented or ameliorated by properly applied antioxidants, preferably natural ones such as green tea, popular drink. The aim this work was see if orally tea brew diminish functional neurotoxicity...
Abstract Blood-brain barrier (BBB) models derived from human stem cells are powerful tools to improve our understanding of cerebrovascular diseases and facilitate drug development for the brain. Yet providing cell-derived endothelial with right signaling cues acquire BBB characteristics while also retaining their vascular identity remains challenging. Here, we show that simultaneous activation cyclic AMP Wnt/β-catenin signaling, inhibition TGF-β pathway in robustly induce properties vitro ....
The complexation of MgII with adenosine 5'-triphosphate (ATP) is omnipresent in biochemical energy conversion, but difficult to interrogate directly. Here we use the spin- 1/2 β-emitter 31 Mg study -ATP 1-ethyl-3-methylimidazolium acetate (EMIM-Ac) solutions using β-radiation-detected nuclear magnetic resonance (β-NMR). We demonstrate that (nuclear) spin-polarized Mg, following ion-implantation from an accelerator beamline into EMIM-Ac, binds ATP within its radioactive lifetime before...
Abstract The complexation of Mg II with adenosine 5′‐triphosphate (ATP) is omnipresent in biochemical energy conversion, but difficult to interrogate directly. Here we use the spin‐ β‐emitter 31 study ‐ATP 1‐ethyl‐3‐methylimidazolium acetate (EMIM‐Ac) solutions using β‐radiation‐detected nuclear magnetic resonance (β‐NMR). We demonstrate that (nuclear) spin‐polarized Mg, following ion‐implantation from an accelerator beamline into EMIM‐Ac, binds ATP within its radioactive lifetime before...
Silybum marianum (milk thistle) has been used for centuries as a herbal medicine the treatment of liver diseases. Its purified active fraction, silymarin, is applied in diseases toxic and viral origin modern therapy. The plant its products are patients suffering from Wilson's disease well with aim protecting consequences copper accumulation.