- Veterinary Equine Medical Research
- Hidradenitis Suppurativa and Treatments
- Musculoskeletal pain and rehabilitation
- Colorectal and Anal Carcinomas
- Mobile Health and mHealth Applications
- Spine and Intervertebral Disc Pathology
- Autoimmune and Inflammatory Disorders Research
- Physical Activity and Health
- Rheumatoid Arthritis Research and Therapies
- Digital Mental Health Interventions
- Shoulder Injury and Treatment
- Maternal and fetal healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Spinal Fractures and Fixation Techniques
- Cerebral Palsy and Movement Disorders
- Endometriosis Research and Treatment
- Migration, Health and Trauma
- Helminth infection and control
- Tendon Structure and Treatment
- Sports injuries and prevention
- Chemotherapy-related skin toxicity
- Meta-analysis and systematic reviews
- Chemotherapy-induced cardiotoxicity and mitigation
- Medication Adherence and Compliance
- Coccidia and coccidiosis research
South Tipperary General Hospital
2016-2020
Trinity College Dublin
2007-2018
Health Service Executive
2018
St. Vincent's University Hospital
2014-2017
University of Limerick
2014-2016
University College Dublin
2003-2015
University of New England
2010-2011
University of Glasgow
2010
University of London
2010
University of Bern
2010
There is a dearth of information on the precise pathogenesis hidradenitis suppurativa (HS), but immune dysregulation implicated.To determine nature response in HS.Skin biopsies - lesional, perilesional (2 cm away) and uninvolved (10 were obtained from patients with HS healthy controls. The expression various cytokines was determined by enzyme-linked immunosorbent assay, flow cytometry real-time polymerase chain reaction.The inflammatory interleukin (IL)-17, IL-1β tumour necrosis factor-α...
Editor—T Eke and colleagues report three cases of severe, symptomatic constriction the visual fields associated with vigabatrin treatment.1 We have had experience a similar case. A 34 year old man who refractory partial onset seizures since age 8 was taking 3000 mg daily (since 1989), carbamazepine 1200 daily, sodium valproate 5000 (both 1982) when he suddenly developed deterioration blurring loss peripheral vision in July 1995. Surface electroencephalography suggested left hemispheric...
To determine the association between owner-reported noise and findings during dynamic respiratory endoscopy (DRE) in a large case series.The sensitivity of for upper tract obstructions horses is low, specificity high.One hundred underwent DRE investigation abnormal and/or poor performance. The with was evaluated.Eighty-five noise. Of these, 82% were found to have one or more obstructive abnormalities DRE. Forty-eight percent reported gurgle, rattle make rough diagnosed solitary palatal...
An experiment was conducted over 2 years on six commercial farms to quantify the costs of gastrointestinal nematode parasitism grazing Merino ewes Northern Tablelands New South Wales. To determine effect worm management practices, three implemented integrated parasite (IPM) strategies and continued implement regionally typical industry practice (TYP). On each farm, 120 born in 2006 mature age were selected at shearing 2007. Of these, 60 flock serially treated with anthelmintics (CAP...
Mucosal ulcers and, occasionally, small granulomas on the axial surface of one or both arytenoid cartilages have been found in TB yearlings presented for post sale endoscopic examination.To determine incidence, characteristics and outcome a group Thoroughbred affected with mucosal cartilage.The incidence ulceration yearling Thoroughbreds is relatively high compared to other upper airway abnormalities; that majority heal uneventfully, although percentage may progress granuloma less commonly,...
Purpose: Establishing physiotherapists’ management of people with rheumatoid arthritis, in addition to their promotion physical activity, is important ascertain if there are educational needs this area.Materials and methods: Physiotherapists from three Irish Chartered Physiotherapy clinical interest groups (N = 457) were invited participate a cross-sectional online questionnaire hosted on SurveyMonkey(R)™.Results: One hundred sixty-eight (168/457; 37%) responded. Exercise prescription...
During numerous biological processes, cell adhesion, migration and spreading are vital. These basic functions regulated by the interaction of cells with their extracellular environment. To examine morphology mechanical changes occurring in mesenchymal stem cultured on a mechanically rigid substrate, atomic force microscopy fluorescence were employed. Investigations revealed both linear geodesic F-actin configurations. No particular characteristics or intra-cellular location implicated...
This study reports on a series of patients who were diagnosed as having had transient lateral patellar dislocation by magnetic resonance imaging (MRI). The images reviewed with specific reference to the medial collateral ligament (MCL), heretofore undescribed concomitant injury. Eighty MRI dislocation. Their mean age was 23.9 years (SD 7.5). Forty (50.0%) co-existent MCL injuries. These injuries classified grade 1 (n = 20), 2 17) and 3 3). results suggest that injury commonly accompanies...