The essential oil of hyssop is widely used in food, pharmaceutical and cosmetic industries throughout the world. Therefore, it very important to know chemical characteristics for economic use enhanced performance end products. This study was carried out determine antimicrobial antioxidant activities Hyssopus officinalis (L.) (Lamiaceae) collected from wild Southeast Anatolian, Turkey. Chemical compositions hydrodistilled oils obtained leaves were analyzed by gas chromatography-mass...

AbstractThis study reports in vitro anticholinesterase, antioxidant and antimicrobial effects of the n-hexane, dichloromethane, ethanol ethanol–water extracts prepared from Pistacia terebinthus L. fruits khinjuk Stocks seeds as well their total phenolic flavonoid contents, fatty acid compositions. Ethanol both species exhibited higher anticholinesterase activity than galanthamine. Among ABTS, DPPH CUPRAC assays, highest capacity was found last one. P. extract being rich content showed best...

It has been previously shown that the aldehyde dehydrogenase (ALDH) family member ALDH1A1 a significant association with acute myeloid leukemia (AML) patient risk group classification and AML cells lacking expression can be readily killed via chemotherapy. In past, however, redundancy between activities of subgroup members ALDH hampered search for conclusive evidence to address role specific genes. Here, we describe bioinformatics evaluation all nineteen genes as prospective actionable...

Increased ROS has been reported to cause a change in E- and N-cadherin levels, consequently promotes migrative behaviors pancreas breast cancer cells. In this study, the effect of sublethal dose H2O2 on PCa cells was investigated.To determine concentration cell proliferation production were examined using WST-1 DCFH-DA assays, respectively. protein mRNA levels investigated by western blotting real-time PCR, The potentials Cytoselect 96-well migration assay.Treatment with results decrease...

It has been previously shown that aldehyde dehydrogenase (ALDH) family member ALDH1A1 a significant association with acute myeloid leukemia (AML) patient risk group classification, and AML cells lacking expression can be readily killed by chemotherapy. In the past, however, redundancy between activities of subgroup members ALDH hampered conclusive evidence for addressing role specific genes. We here describe bioinformatics evaluation all nineteen genes as prospective actionable targets...

AbstractIn the present study, seven thyme species Origanum onites, O. vulgare var. hirtum, gracile, syriacum, Satureja hortensis, Thymbra spicata, and Thymus vulgaris were used. The essential oils of these plants obtained by hydrodistillation method. Antimicrobial activities against microorganisms, including multiple antibiotic-resistant bacteria, investigated using disc diffusion All used in this study very effective Gram-positive Gram-negative which included resistant strains. tested...

The genus Nepeta (Lamiaceae) and Achillea (Asteraceae) are widely distributed in Turkey. In this study, the essential oils of italica L. filipendulina LAM. collected from Dicle district Diyarbakir province Southeast Anatolia Hakkari East Turkey, were obtained by hydrodistillation aerial parts. analyzed gas chromatography-mass spectrometry GC Clarus 600-MS 600 C (Perkin Elmer) microelements Perkin Elmer Optima 2100 DV ICP OEMS, also antioxidant activity DPPH radical scavenging assay. showed...

A new oxovanadium(IV) complex of the Schiff base obtained by condensation 1,2-bis(p-aminophenoxy)ethane with 2-hydroxynaphthalin-1-carbaldehyde was synthesized. The characterized elemental analysis, magnetic measurements, mass spectral data, UV–visible and IR spectra. Stability constants thermodynamic values for complexation between Cu(NO3)2, Zn(NO3)2·6H2O, Ni(NO3)2·6H2O VOSO4·5H2O ligand in 80% dioxane/water were determined conductance measurements. Ni(II) Cu(II) complexes synthesized a...

Bu çalışmada, anason (Pimpinellaanisum L.) ve kimyon (Cuminum cyminum) tohumlarınınuçucu yağ bileşenleri ile bu yağların antimikrobiyal antioksidanözelliklerinin belirlenmesi amaçlanmıştır. Uçucu GC / MS cihazıile belirlenmiştir. Yağların özellikleri disk difüzyon yöntemiile Gram pozitif (Staphylococcus aureus ATCC 25923, Streptococcuspyogenes 19615), negatif (Escherichia coli 25922, Pseudomonasaeruginosa 27853) bakteri maya (Candida albicans 10231)kullanılarak Antioksidan ise DPPH serbest...

Breast cancer (BCa) is the most frequently diagnosed malignant tumor in women and also one of leading causes cancer-related death. Most breast tumors are hormone-dependent estrogen signaling plays a critical role promoting survival behaviors these cells. Estrogen involves ligand-activated cytoplasmic receptors that translocate to nucleus with various co-regulators such as steroid receptor co-activator (SRC) family members, bind promoters target genes regulate their expression. SRC-3 member...

Alkylaminophenols are synthetic derivatives well known for their anticancer activity. In this work, we report the antimicrobial and antioxidant activity of such compounds. A series (4,5,6) alkylaminophenol compounds were prepared with very high yields by Petasis reaction. Synthesized characterized 1 H-NMR 13 C-NMR. The obtained tested against Gram-positive Gram-negative bacteria. compound 4 showed at a concentration 10 mg/mL, while 6 on S. aureus. Phenolic have attracted attention due to...

ABSTRACTABSTRACTBacillus subtilis was grown in mediums containing various schiff base (N,N'-Bis(salicylidene)-l,4-diaminobutane) that include transition metal complexes and ions. The effects of these substances on the production secreted amylase, membrane bound amylase as well transport bacterial growth were investigated. results revelaed synthesis rate isolated from membranes stimulated by separately contains Mn(II) Zn(II)complexes. In addition, Zn(II) increased through membrane, while...

This work is focused on the synthesis of leucyl-glycine-functionalized γ-Fe2O3 magnetic nanoparticles coated by polydioxanone (γ-Fe2O3-CA-Leu-Gly-PDX) as a polyethersulphone (PES) membrane for biotechnological applications. The physicochemical characteristics were investigated FT-IR, SEM, XRD, vibrating sample magnetometer (VSM), and ICP-OES. present investigation also centered several biological activities γ-Fe2O3-CA-Leu-Gly-PDX. 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging metal...

Hypericum (Hypericaceae) species are extensively used in several fields such as traditional medicine, food and crop protection. Despite its usage many fields, the identification of genotoxic potential this herb is still incomplete. In study, we evaluated effects petroleum ether, hexane, ethyl acetate, methanol extract lysimachioides Boiss. var. by Ames Salmonella/microsome test SOS chromotest. The mutagenic activity extracts was investigated using Salmonella typhimurium strains TA98 TA100...

This study was carried out to investigate effects of microwave irradiation on cell differentiation and SOS repair system in Bacillus subtilis rec+ YB 886 rec derivatives A4. Amount a specific protein that shynthesed during DNA damage by binding din C promoter region increased bacteria. More increasing were determined amount the Ultraviolet treatment. If DNA, RNA are taken into consideration, it has observed decreased (P>0.05) but not statically significant, (p<0.05) little increasing, may be...

Kabaklı Göleti'nden (37° 55' 23K, 40°17' 40D, Diyarbakır) izole edilen ve Chlorella vulgaris Beyerinck Chroococcus limneticus Lemmermann olarak tanımlanan mikroalg türlerinin metanol ekstraktlarının antimikrobiyal, antioksidan mutajenik aktiviteleri araştırıldı. En yüksek aktivite, 100 µg/ml konsantrasyonunda C. (%36,63) (%28,48) için ABTS•+ analizinde gözlendi. DPPH CUPRAC analizleri zayıf aktivite gösterdi. Antioksidan pozitif kontrollerle karşılaştırıldığında her iki tür de önemli...

The mutagenicity and antimutagenicity of leaves flower extract Cynara syriaca Boiss were studied with Ames assay in Salmonella typhimurium TA98 TA100 strains. While did not show any mutagenic effects against all the tester strains or without metabolic activation, showed effect strain activation. On other hand, it has been observed that extracts have antimutagenic activity mutations induced by sodium azide daunomycin. antimicrobial was determined disc diffusion MIC value. Both possess weak...