A5010685278- Cancer and Skin Lesions
- Psoriasis: Treatment and Pathogenesis
- Urticaria and Related Conditions
- Autoimmune Bullous Skin Diseases
- Dermatology and Skin Diseases
- Autoimmune and Inflammatory Disorders Research
- Cutaneous Melanoma Detection and Management
- Tumors and Oncological Cases
- Drug-Induced Adverse Reactions
- Contact Dermatitis and Allergies
- Melanoma and MAPK Pathways
- Skin and Cellular Biology Research
- Nonmelanoma Skin Cancer Studies
- Dermatological and COVID-19 studies
- Neonatal skin health care
- Nail Diseases and Treatments
- Child Abuse and Related Trauma
- Pressure Ulcer Prevention and Management
- Optical Coherence Tomography Applications
- Obsessive-Compulsive Spectrum Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Genetic and rare skin diseases.
- Immunodeficiency and Autoimmune Disorders
- NF-κB Signaling Pathways
- Dupuytren's Contracture and Treatments
Cincinnati Children's Hospital Medical Center
2012-2016
University of Cincinnati Medical Center
2012-2015
Adult and Pediatric Dermatology
2015
University of Cincinnati
2014
Children's Hospital of Philadelphia
2006-2011
University of Pennsylvania
2007-2011
Philadelphia University
2010-2011
Hospital of the University of Pennsylvania
2007-2010
GTx (United States)
2006
Apremilast, an oral phosphodiesterase 4 inhibitor, regulates immune responses associated with psoriasis.ESTEEM 2 evaluated the efficacy and safety of apremilast 30 mg twice daily for moderate-to-severe plaque psoriasis.This phase III, double-blind, placebo-controlled trial randomized adults to or placebo (2 : 1). At week 16, patients switched apremilast. 32, achieving ≥ 50% reduction in Psoriasis Area Severity Index (PASI 50) were rerandomized (1 1) continue receive placebo. Upon loss PASI...
The formation of a nodule within congenital melanocytic nevus (CMN) raises concerns about possible melanoma. Most new nodular growths that develop during childhood, however, are benign proliferative nodules (PN); melanoma is very rare. distinction from PN can at times be difficult clinically and histopathologically, requiring ancillary molecular tests for diagnosis. Although the application methods has revealed insights into mutational genomic landscape childhood melanomas, little known...
<h3>Background</h3> Impaired skin integrity in patients with Netherton syndrome (NS) results significant systemic absorption of topically applied medications. Some have advocated the administration pimecrolimus, 1%, topical cream for treatment NS. Insufficient data exist regard to its safety, absorption, and efficacy. <h3>Observations</h3> An exploratory study was conducted involving 3 children NS who received twice-daily application over 18 months. There were no notable abnormalities...
Abstract: Medallion‐like dermal dendrocyte hamartomas are rare congenital cutaneous lesions, with only three occurrences reported in the English language literature. They present at birth as asymptomatic circular, oval, or triangular well‐circumscribed, atrophic patches. Typically, they have an erythematous yellow‐brown hue and a characteristic pliable, wrinkled surface; subtle telangiectases may also be appreciated. misdiagnosed atrophoderma, cutis aplasia, anetoderma. All patients been...
Abstract: An otherwise‐healthy 13‐year‐old girl with previously normal nails developed longitudinal pigmented bands on multiple fingernails. Physical examination revealed faintly fingernails and the left fifth toenail. We believed that cause of was onychophagia‐induced melanonychia, a rare phenomenon, which emphasizes need for dermatologists to question patients melanonychia about their nail biting habits because they may not be forthcoming this information.
Abstract: We report a case of solitary infantile myofibroma masquerading as an ulcerated hemangioma. Infantile is rare soft tissue tumor that has good prognosis in the form. It may be difficult to distinguish clinically from more common tumors infancy such hemangioma or other entities and therefore requires biopsy for definitive diagnosis.
To evaluate the safety and efficacy of our institutional beta-blocker protocol for treatment complicated infantile hemangiomas (IH).A retrospective descriptive study 76 infants/children with IH treated oral propranolol at Children's Hospital Philadelphia between June 2008 August 2010 was performed, assessing both propranolol. Based on preliminary data showing hemangioma recrudescence off-treatment, we reviewed 9 additional patients December 2011.Mild adverse events included asymptomatic...
Granulomatous vulvitis (GV) and granulomatous cheilitis (GC) are inflammatory conditions characterized by painless swelling of the vulva lips, respectively (1,2). When a patient presents with GV and/or GC, infectious process disease must be ruled out (2,3). The differential diagnosis GC include rosacea, lupus vulgaris, mycobacterial infections, sarcoidosis, Anderson-Fabry disease, metastatic Crohn foreign body granuloma (2). Other causes chronic vulval edema angioneurotic edema, malignant...