A5021060196- Trace Elements in Health
- Medication Adherence and Compliance
- RNA Research and Splicing
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Iron Metabolism and Disorders
- Pharmaceutical Practices and Patient Outcomes
- Misinformation and Its Impacts
- Organizational Management and Innovation
- HIV/AIDS Research and Interventions
- Blood Pressure and Hypertension Studies
- Parkinson's Disease Mechanisms and Treatments
- COVID-19 epidemiological studies
- Healthcare Systems and Technology
- Genomics and Rare Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Privacy, Security, and Data Protection
- RNA regulation and disease
- Information Architecture and Usability
- COVID-19 Digital Contact Tracing
- RNA and protein synthesis mechanisms
- Adolescent and Pediatric Healthcare
Predict (France)
2024
Institut de Biologia Evolutiva
2016-2023
Universitat Pompeu Fabra
2016-2023
Barcelona Biomedical Research Park
2022-2023
Open Evidence
2022
ABSTRACT Background The analysis of coverage depth in next‐generation sequencing data allows the detection gene dose alterations. We explore frequency such structural events a Spanish cohort sporadic PD cases. Methods Gene alterations were detected with eXome‐Hidden Markov Model (XHMM) software from resequencing available for 38 Mendelian and other risk loci 394 individuals (249 cases 145 controls) subsequently validated by quantitative PCR. Results identified 10 patients exon dosage PARK2,...
Introduction High levels of adoption and usage for the COVID Tracing Apps (CTA) among population is a stipulated prerequisite success implementation these apps, aiming to mitigate pandemic track spreading virus more efficient effectively. In current study, main objective was investigate individuals' preferences in intention download COVID-19 tracing app pilot-study both Netherlands Turkey. Methods We conducted discrete choice experimental study through an online survey two countries (the [ N...
Patients with polypharmacy suffer from complex medical conditions involving a large healthcare burden. This study aimed to describe the characteristics and utilization of primary care (PC) hospital (HC) factors associated in chronic patients polypharmacy, stratifying by adjusted morbidity groups (AMG) risk level, sex age, comparing non-polypharmacy.Cross-sectional conducted Spanish basic area. Studied were those over 18 years diseases identified AMG tool Madrid electronic clinical record,...
Zinc is an essential micronutrient with a tightly regulated systemic and cellular homeostasis. In humans, some zinc transporter genes (ZTGs) have been previously reported as candidates for strong geographically restricted selective sweeps. However, since homeostasis maintained by the joint action of 24 ZTGs, other more subtle modes selection could also facilitated human adaptation to availability. Here, we studied whether complete set ZTGs are enriched signals positive in worldwide...
<title>Abstract</title> Although immunization through vaccination is one of the most successful public health interventions, actual coverage program has decreased rapidly over last years due to increased vaccine hesitancy. Cognitive biases have been shown play an important role in affecting In this study, we conducted a randomized-control trial (N = 2000, N 1000 from Spain and Bulgaria), where subjects were randomly assigned condition. The conditions differed by whether electronic Product...
SLC30A9 encodes a ubiquitously zinc transporter (ZnT9) and has been consistently suggested as candidate for positive selection in humans. However, no direct adaptive molecular phenotype demonstrated. Our results provide evidence directional operating two major complementary haplotypes Africa East Asia. These are associated with differential gene expression but also differ the Met50Val substitution (rs1047626) ZnT9, which we show is found homozygosis Denisovan genome displays accompanying...
Abstract SLC30A9 encodes a ubiquitously zinc transporter (ZnT9) and has been consistently suggested as candidate for positive selection in humans. However, no direct adaptive molecular phenotype demonstrated. Our results provide evidence directional operating two major complementary haplotypes Africa East Asia. These are associated with differential gene expression but also differ the Met50Val substitution (rs1047626) ZnT9, which we show is found homozygosis Denisovan genome displays...