- Trace Elements in Health
- RNA and protein synthesis mechanisms
- Hepatitis C virus research
- RNA modifications and cancer
- Cancer Genomics and Diagnostics
- SARS-CoV-2 and COVID-19 Research
- RNA Research and Splicing
- Lung Cancer Treatments and Mutations
- COVID-19 Clinical Research Studies
IrsiCaixa
2022
Universitat Pompeu Fabra
2022
Institut de Biologia Evolutiva
2022
Barcelona Biomedical Research Park
2022
Hospital Clínic de Barcelona
2021
We analyzed humoral and cellular immune responses induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger RNA (mRNA) vaccines in people with human immunodeficiency virus (HIV; PWH) who had CD4+ T-cell counts <200/µL (HIV<200 group).
Analysis of circulating free DNA (cfDNA) by the real-time PCR cobas® EGFR Mutation Test v2 (cobas® Test) is a diagnostic approach used in clinical practice for characterization advanced non-small cell lung cancer (NSCLC) patients. The test additionally outputs semiquantitative index (SQI) which reflects proportion mutated versus wild-type copies gene cfDNA with potential use as biomarker. CfDNA concentration and fragmentation pattern have also shown utility biomarkers We evaluated...
Zinc is an essential micronutrient with a tightly regulated systemic and cellular homeostasis. In humans, some zinc transporter genes (ZTGs) have been previously reported as candidates for strong geographically restricted selective sweeps. However, since homeostasis maintained by the joint action of 24 ZTGs, other more subtle modes selection could also facilitated human adaptation to availability. Here, we studied whether complete set ZTGs are enriched signals positive in worldwide...