A5034104118- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Liver physiology and pathology
- Biochemical effects in animals
- Pediatric Hepatobiliary Diseases and Treatments
- Neuroscience and Neuropharmacology Research
- Drug Transport and Resistance Mechanisms
- Memory and Neural Mechanisms
- Circadian rhythm and melatonin
- Mast cells and histamine
- Clinical Nutrition and Gastroenterology
- Wound Healing and Treatments
- Stress Responses and Cortisol
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Mesenchymal stem cell research
- Drug-Induced Hepatotoxicity and Protection
- Anesthesia and Neurotoxicity Research
- Nitric Oxide and Endothelin Effects
- Anatomy and Medical Technology
- Heme Oxygenase-1 and Carbon Monoxide
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiac, Anesthesia and Surgical Outcomes
- Ethics and bioethics in healthcare
- Reproductive System and Pregnancy
Universidad Peruana Cayetano Heredia
2013-2024
Universidade Federal da Bahia
2024
Universidad Nacional de Colombia
2015-2021
Universidad Complutense de Madrid
2010-2020
Hospital Universitario Nuestra Señora de Candelaria
2020
Hospital Nacional Cayetano Heredia
2013-2017
Pontificia Universidad Javeriana
1980-2016
Asociación Colombiana de Facultades de Ingeniería
2014
Universidad de Oviedo
2001-2011
KTH Royal Institute of Technology
2011
Obstructive cholestasis causes hepatic cirrhosis and portal hypertension. The pathophysiological mechanisms involved in the development of liver disease are multiple linked. We propose grouping these according to three phenotypes mainly expressed interstitial space order integrate them.Experimental extrahepatic is model most frequently used study obstructive cholestasis. early alterations described experimental models would produce an ischemia/reperfusion phenotype with oxidative nitrosative...
Inflammation is increasingly recognized as an important component of tumorigenesis, although the mechanisms involved are not fully characterized. The invasive capacity cancers reflected in classic metastatic cascade: tumor (T), node (N) and metastasis (M). However, this staging system for cancer would also have a tumoral biological significance. To integrate that control inflammatory response actual cancer. It considered both processes inflammation cancer, three successive phenotypes...
Abstract It is known that expression of glial fibrillary acidic protein (GFAP) as an astrocyte‐specific marker can be regulated by levels circulating gonadal steroids during postnatal development. In addition, astrocytes play important role in the physiology hippocampus, a brain region considered sexually dimorphic at neuronal level rodents. To evaluate contribution cells to gender‐related differences we estimated number GFAP‐immunoreactive (GFAP‐IR) hippocampus (CA1 and CA3 areas, dorsal...
Abstract Post-traumatic inflammation is formed by molecular and cellular complex mechanisms whose final goal seems to be injured tissue regeneration. In the skin -an exterior organ of body- mechanical or thermal injury induces expression different inflammatory phenotypes that resemble similar expressed during embryo development. Particularly, involved in gastrulation return. This a developmental phase delineates three embryonic germ layers: ectoderm, endoderm mesoderm. Consequently,...
Enteropathy characterized by vascular and inflammatory alterations in the submucosa mucosa has been described patients with portal hypertension.To verify theory of etiopathogenesis experimental hypertensive duodenopathy, a prehepatic hypertension model based on development single triple partial ligation vein was used rat.Five rats each group (male Wistar, 230-255 g) were subjected to (group II) or III) then compared 5 control animals I, no operation). The sacrificed 6 weeks later analyze...
A surgical technique based on the development of a triple stenosing ligation is used to worsen complications inherent prehepatic chronic portal hypertension. The results have been compared with those obtained in rats single-portal ligation. An increase ( p < .05) body, liver, spleen, and kidney weights as well decrease .001) testes weight body ratio were produced both groups animals. In addition, variability weights, particularly liver weight, stands out. incidence portosystemic portohepatic...
Abstract Background: Because most of the characteristics portal hypertensive enteropathy can be explained on basis increased levels mast cell mediators, purpose present paper was to study splanchnic infiltration. Methods: Duodenum, jejunum, ileum and mesenteric lymph node complex infiltration by cells assayed a stereological technique in control rats (group I; n = 5) an experimental model hypertension (the vein‐stenosed rat, group II; at 6 weeks after operation. Results: Intestinal animals...