The incidence of melanoma cutaneous and the mortalities rates are rising in most countries worldwide.to describe histopathological characteristics melanoma, according to criteria established by Brazilian Group Melanoma, evaluate early diagnosis a cancer treatment referral center.we performed cross-sectional descriptive study cases primary identified after excisional biopsy processed at pathology laboratory Complexo Hospitalar Santa Casa between Jan 1st 2000 15th 2005. following variables...

Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be factor considered the decision perform this procedure. Objective: To evaluate association between and metastases caused by melanoma. Methods: Cross-sectional study with 137 records submitted sentinel from 2003 2015. clinical variables were age, sex topography lesion. histopathological assessed were:...

Mutations in the p53 tumor suppressor gene are present approximately 50% of all human cancers. We sought to determine frequency and type mutations squamous cell carcinomas (SCC) oral cavity a Brazilian population. To identify we used PCR-SSCP tissue microdissected from paraffin- embedded fresh-frozen sections followed by direct sequencing SSCP bands with altered electrophoretic mobility. identified 40% SCC analyzed. The were broad spectrum, preponderance G --> A transitions an apparent...

this was an epidemiological study on trochanteric bursitis at the time of performing total hip arthroplasty. sixty-two sequential patients who underwent arthroplasty due to osteoarthrosis, without any previous history bursitis, were evaluated. The bursas collected and evaluated histologically. there 35 female (56.5%) 27 male (43.5%), with a mean age 65 years (±11). Trochanteric conformed histologically in nine (14.5%), whom six (66.7%) three (33.3%). 14.5% analyzed presented inflammation...

Abstract: Patients with large congenital melanocytic nevus (LCMN) have a high risk of developing malignant melanoma (MM) and other malignancies. We report case mesenchymal malignancy that best fit the diagnosis peripheral nerve sheath tumor subsequent development MM from LCMN. There are no previous reports second primary neoplasm arising

Esophageal cancer is an aggressive disease that generally has a poor prognosis. Patients affected by the usually present with signs and symptoms related to local growth of tumor, gastrointestinal bleeding nutritional impairment. Skin metastases are rare events, associated advanced stage survival.We report case 51-year-old man who presented general status, dysphagia, weight loss skin lesions disseminated throughout body. Endoscopic examination revealed presence esophageal squamous cell...

A 59-year-old white man was referred for evaluation of epigastric pain that radiating to his back and a 5-kg weight loss over 6 months. computed tomography (CT) scan revealed heterogeneous low-attenuation tumor, measuring 5 cm in size, adjacent the celiac artery pancreatic body ([Fig. 1]). Sectorial endoscopic ultrasound (GF-UCT140-AL5; Olympus America Inc., New York, USA), coupled an unit (Prosound alfa-5 SX; Aloka), detected retroperitoneal well-circumscribed, hypoechoic mass, which...

fazer um estudo epidemiológico da bursite trocantérica no momento feitura artroplastia total do quadril (ATQ). foram avaliados 62 pacientes, sequenciais, submetidos à ATQ por osteoartrose, sem história prévia de trocantérica. As bursas coletadas e avaliadas histologicamente. observados 35 pacientes sexo feminino (56,5%) 27 masculino (43,5%), com média 65 anos (+/−11). A foi confirmada histologicamente em nove (14,5%), seis (66,7%) três (33,3%) masculino. das analisadas, 14,5% apresentaram...

Neonatal lupus erythematosus is an autoimmune disease produced by the passage of maternal antinuclear antibodies and extractable nuclear antigen through placenta. At moment diagnosis, mothers are asymptomatic in 40 to 60% cases. The most common manifestations cutaneous lesions congenital heart block. findings variable usually begin within first weeks or months life. Congenital a variant neonatal erythematosus. We present one case erythematous, showing variability this disease.

To simulate the effects of previous wide cutaneous melanoma excision in sentinel lymph node (SLN) biopsy feasibility through a change radiotracer injection site.Thirty-three patients with underwent two preoperatory lymphoscintigraphic studies. In first, radiopharmaceutical was injected intradermally 0.3 cm away from lesion/scar. Dynamic images were acquired to find SLN. On following day, procedure repeated 1 farther sites. The number nodes and sites drainage compared findings first study....

Mixed epithelial and stromal tumor (MEST) represents a recently described biphasic kidney neoplasm, which predominantly affects perimenopausal females.The authors report the case of young male patient with MEST exhibiting positivity for estrogen progesterone receptors.Computed tomography/magnetic resonance imaging (CT/MRI) showed an expansive lesion affecting right kidney.Grossly, solid-cystic was identified, measured 5.7 × 3.5 2.4 cm.On microscopic examination, constituted by elements,...

Giant cell tumor of the tendon sheath is a benign soft tissue most frequent between third and fifth decades life. It can mimic make differential diagnoses with several hand tumors. Definitive diagnosis treatment choice are reached complete resection histopathological examination. Here we describe case clinical presentation similar to that myxoid cyst.

The capacity for prognostic prediction of cutaneous melanoma, one the most aggressive cancers, is still difficult due to tumor heterogeneity and lack reliable markers. objective this study correlate, through immunohistochemistry, a Ki-67 Kindlin-1 staining in malignant melanomas with prognosis disease. A historical cohort study. Immunohistochemistry, using mouse anti-human monoclonal antibodies, was performed tissue blocks from primary melanoma patients treated between 2006 2014 at our...

Resumo Relato de caso paciente pediátrico com diagnóstico sarcoma histiocítico ósseo em escápula, submetido à ressecção oncológica (cirurgia Tikhoff-Linberg tipo II), retorno às atividades prévias e livre doença após 24 meses seguimento.