A5019585280- Drug-Induced Hepatotoxicity and Protection
- Flavonoids in Medical Research
- Drug Transport and Resistance Mechanisms
- Natural product bioactivities and synthesis
- Pharmacogenetics and Drug Metabolism
- Vitamin C and Antioxidants Research
- Analytical Methods in Pharmaceuticals
- Gastrointestinal motility and disorders
- Antibiotic Use and Resistance
- Liver Disease Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
- Gastroesophageal reflux and treatments
- Intestinal and Peritoneal Adhesions
- Therapeutic Uses of Natural Elements
- Vitamin D Research Studies
- Plant chemical constituents analysis
- Antibiotics Pharmacokinetics and Efficacy
- Cell death mechanisms and regulation
- Clinical Laboratory Practices and Quality Control
- Pharmaceutical Practices and Patient Outcomes
- Essential Oils and Antimicrobial Activity
- Child and Adolescent Health
- Healthcare cost, quality, practices
- Cholinesterase and Neurodegenerative Diseases
- Sepsis Diagnosis and Treatment
Mashhad University of Medical Sciences
2011-2025
University of Surrey
2002
Peritoneal adhesion (PA) is an abnormal connective tissue that usually occurs between tissues adjacent to damaged organs during processes such as surgery. In this study, the anti-inflammatory and antioxidant effects of Portulaca oleracea (PO) were investigated against postoperative-induced peritoneal adhesion.Thirty healthy male Wistar rats (220 ± 20 g, 6-8 weeks) randomly divided into four groups: (1) normal, (2) control (induced adhesion), (3) (4) PO extracts received 100 or 300 mg/kg/day...
Abstract Scutellaria is a genus of Lamiaceae with known antiproliferative potentials. litwinowii Bornm. & Sint. ex one the Iranian species Scutellaria. Although there are widespread reports about cytotoxic and antitumor effects some this genus, research on molecular mechanism responsible for anticancer S. has not yet been conducted. In current study, apoptotic 2 myeloid cell lines, apoptosis-proficient HL60 cells apoptosis-resistant K562 cells, were analyzed. An increase in activity...
Neobaicalein is one of the rich plant flavonoids isolated from roots Scutellaria spp. In this study, we evaluated and compared cytotoxic activity related apoptosis mechanisms neobaicalein litwinowii Bornm. & Sint. ex Bornm on apoptosis-proficient HL-60 cells apoptosis-resistant K562 cells.Cell viability, cell apoptosis, caspase activity, apoptosis-related protein expression were measured using MTS assay, propidium iodide (PI) staining flow cytometry, western blot analysis,...
One thousand Iranians belonging to 5 different Iranian ethnic groups were tested for butyrylcholinesterase (BChE) activity and phenotype. The phenotype was measured as percent inhibition in the presence of dibucaine. It found that population had an extraordinarily high frequency atypical variant butyrylcholinesterase. 70% 80% carried mutation (Asp70Gly) on one allele. This contrasts with European American populations where only 4% carry is known be associated prolonged apnea after...
Background: In pediatrics, many drugs are used without marketing authorization. Recommendations often based on clinical experience. Therefore, the risk of inappropriate prescription (IP) is high. It necessary to have a tool for pediatric IP detection. Objectives: This study was performed develop and validate Pediatrics: Omission Prescriptions Inappropriate (POPI) screening facilitate its use in practice Iran. Methods: Using forward- backward-translation procedures, an efficient effective...