A5017311650- Medicinal Plants and Neuroprotection
- Saffron Plant Research Studies
- Nigella sativa pharmacological applications
- Pharmacological Effects of Natural Compounds
- Sleep and Wakefulness Research
- Essential Oils and Antimicrobial Activity
- Plant biochemistry and biosynthesis
- Antioxidants, Aging, Portulaca oleracea
- Medicinal Plant Extracts Effects
- Phytochemistry and Biological Activities
- Intestinal and Peritoneal Adhesions
- Biochemical Analysis and Sensing Techniques
- Ziziphus Jujuba Studies and Applications
- Natural product bioactivities and synthesis
- Natural Antidiabetic Agents Studies
- Neurological Disease Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Medicinal Plants and Bioactive Compounds
- Complementary and Alternative Medicine Studies
- Advances in Cucurbitaceae Research
- Diet and metabolism studies
- Dermatology and Skin Diseases
- Hydrogen's biological and therapeutic effects
- Neurobiology and Insect Physiology Research
- Pharmacology and Obesity Treatment
Mashhad University of Medical Sciences
2016-2025
Multidisciplinary Digital Publishing Institute (Switzerland)
2019
University of Naples Federico II
2019
October 6 University
2016
Ghaem Hospital
2016
GTx (United States)
2016
Razi Hospital
2016
Ferdowsi University of Mashhad
2006
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are classified as two complications arising from various conditions such sepsis, trauma, inflammation. Previous studies have shown that the extract of leaves Portulaca oleracea (PO) possesses anti-inflammatory anti-oxidant activities. In present study, effects PO (50–200 mg/kg) dexamethasone (Dexa; 1.5 on lipopolysaccharide (LPS)-induced ALI were investigated. Subsequentially, wet/dry ratio; white blood cells (WBC);...
Abstract In previous studies, the relaxant, anticholinergic (functional antagonism) antihistaminic, effects of Nigella sativa have been demonstrated on guinea‐pig tracheal chains. present study, prophylactic effect boiled extract N. asthmatic disease was examined. Twenty‐nine adults were randomly divided into control group (14 patients) and study (15 patients), they studied for 3 months. 15 mL/kg 0.1 g% in a placebo solution administrated daily throughout study. Asthma symptom score, asthma...
Type-one diabetes (T1D), a chronic autoimmune disease with marked inflammatory responses, is associated infertility complications and implications. Based on the anti-diabetic, antioxidant, anti-hyperlipidemic potential of Portulaca oleracea (PO), this study aimed to evaluate protective effect plant extract streptozotocin-induced type-I-diabetes-associated reproductive system dysfunction inflammation.Male rats were randomly divided into four experimental groups: control, diabetic, treatment/s...
Background: Neuroimmune factors have been proposed as contributors to the pathogenesis of depression. Beside other therapeutic effects including neuroprotective, antioxidant, anticonvulsant and analgesic effects, Nigella sativa its main ingredient, thymoquinone (TQ), shown anti-inflammatory effects. In present study, hydro-alcoholic extract was investigated on lipopolysaccharide- induced depression like behavior in rats. Materials Methods: 50 male Wistar rats were divided into 5 groups:...
Postoperative adhesions are regarded as the major complication following abdominal surgery. Rosmarinus officinalis has shown antioxidative and anti-inflammatory effects. Therefore, we aimed to assess influence of 70% v/v hydro-ethanolic extract aerial parts R. against postoperative in a rat model. Forty-eight male Wistar rats (190 ± 20 g) were divided into six groups eight: group 1 = normal group, without any surgical procedures, 2 control 3 vehicle 3, 4, 5 experimental receiving mL 2, or 1%...
Postoperative peritoneal adhesions are considered the major complication following abdominal surgeries. The primary clinical complications of adhesion intestinal obstruction, infertility, pelvic pain, and postoperative mortality. In this study, regarding anti-inflammatory antioxidant activities Crocus sativus, we aimed to evaluate effects sativus on prevention postsurgical-induced adhesion. Male Wistar-Albino rats were used investigate preventive C. extract (0.5%, 0.25% 0.125% w/v) against...
Abstract The dried flower bud of Syzygium aromaticum L. ( S. ) (Myrtaceae), cloves, have been used for their analgesic and anti‐inflammatory activities. Peritoneal adhesion (PA) is the most common complication abdominal pelvic surgeries, which causes significant adverse effects severe economic burden. present study aimed to evaluate preventive effect extract (SAE) on PA formation in a rat model. Male Wistar 8‐week‐old rats were randomly divided into sham, control (received vehicle),...
Premenstrual syndrome (PMS) is a common disease that negatively impacts women's quality of life. This study aimed to compare the effects Vitagnus, soy, and Vitagnus-soy combination on PMS in students. triple-blind, three-arm clinical trial was conducted 108 students with living dormitory Mashhad University Medical Sciences from September 2022 October 2023. Eligible participants diagnosed moderate severe over two menstrual cycles, using Calendar Experiences form, were randomly assigned one...
The effects of a polyherbal compound, containing six plants (Allium sativum, Cinnamomum zeylanicum, Nigella sativa, Punica granatum, Salvia officinalis and Teucrium polium) were tested on biochemical parameters in streptozotocin-induced diabetic rats. Streptozotocin caused an approximately 3-fold increase fasting blood sugar level after 2 days. control rats showed further glucose 30 days (384 ± 25 mg/dl day versus 280 12 2,<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
In the present study, effect of aqueous extracts saffron on morphine-induced memory impairment was investigated. On training trial, mice received an electric shock when animals were entered into dark compartment. Twenty-four and forty-eight hours later, time latency for entering compartment recorded defined as retention trial. The divided (1) control, (2) morphine which before in passive avoidance test, (3–5) three groups treated by 50, 150 450 mg/kg extract (6 7) two other morphine-treated...
Background: Sleep disorders are accompanied by several complications, and currently used soporific drugs can induce unwanted effects such as psychomotor impairment, tolerance, amnesia, rebound insomnia.Objectives: The present study was carried out to investigate if Ocimum basilicum has a sleep-prolonging effect.Materials Methods: This work an experimental on 72 mice which were randomly divided into 9 groups: saline (control); diazepam (3 mg/kg, positive control); hydro-alcoholic extract...