Mohammad Derakhshan

ORCID: 0000-0002-4052-3119
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About
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Research Areas
  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • vaccines and immunoinformatics approaches
  • Diagnosis and treatment of tuberculosis
  • Bacteriophages and microbial interactions
  • Pneumonia and Respiratory Infections
  • Infectious Diseases and Tuberculosis
  • Phytochemistry and Biological Activities
  • Primary Care and Health Outcomes
  • Immunotherapy and Immune Responses
  • Inhalation and Respiratory Drug Delivery
  • Empathy and Medical Education
  • Protein purification and stability
  • T-cell and Retrovirus Studies
  • Hepatitis B Virus Studies
  • Antibiotic Resistance in Bacteria
  • Helicobacter pylori-related gastroenterology studies
  • Advanced Drug Delivery Systems
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Monoclonal and Polyclonal Antibodies Research
  • Phytochemistry and Bioactive Compounds
  • Galectins and Cancer Biology
  • Eosinophilic Esophagitis
  • Escherichia coli research studies
  • Autophagy in Disease and Therapy

Mashhad University of Medical Sciences
2016-2025

Tarbiat Modares University
2017

Ghaem Hospital
2010-2011

This paper investigates the effectiveness of GPT-4o-2024-08-06, one Large Language Models (LLM) from OpenAI, in detecting business process anomalies, with a focus on rework anomalies. In our study, we developed GPT-4o-based tool capable transforming event logs into structured format and identifying reworked activities within logs. The analysis was performed synthetic dataset designed to contain anomalies but free loops. To evaluate anomaly detection capabilities GPT 4o-2024-08-06, used three...

10.48550/arxiv.2502.06918 preprint EN arXiv (Cornell University) 2025-02-10

Pharmacogn Mag,2010,6,24,282-285.DOI:10.4103/0973-1296.71791Published:October 2010Type:Original ArticleAuthors:S Niazmand, E Khooshnood, and M Derakhshan Author(s) affiliations:S Niazmand1, Khooshnood2, Derakhshan3 1Department of Physiology, Medical School, Mashhad University Sciences, Mashhad, Iran 2Department Biology, Sciences Azad 3Department Clinical Microbiology Virology in Ghaem Hospital Buali Research Institute, Abstract:Background: Achillea is a plant widely used traditional medicine...

10.4103/0973-1296.71791 article EN Pharmacognosy Magazine 2010-01-01

Pharmacognosy Magazine,2011,7,27,260-264.DOI:10.4103/0973-1296.84244Published:August 2011Type:Original ArticleAuthors:Seed Niazmand, Maryam Esparham, Tahereh Hassannia, and Mohammad Derakhshan Author(s) affiliations:Seed Niazmand1, Esparham2, Hassannia3, Derakhshan4 1Department of Physiology, Cardiovascular Research Center, Mashhad, Iran 2Department Biology, Sciences School, Azad University 3Department Internal Medicine Medical Mashhad (MUMS), 4Department Clinical Microbiology Virology in...

10.4103/0973-1296.84244 article EN Pharmacognosy Magazine 2011-01-01

A new strategy in recent studies is using effective tuberculosis (TB) subunit vaccines combined with appropriate carriers and adjuvants which have shown promising results preclinical clinical studies. The aim of the present study was to evaluate PLGA:DDA hybrid nanoparticles (NPs) for subcutaneous delivery a novel multistage vaccine along MPLA adjuvant against Mycobacterium (M. tuberculosis). PLGA NPs containing HspX/EsxS fusion protein were prepared by double emulsion method (w/o/w). After...

10.22038/ijbms.2019.33962.8079 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2019-08-01

Game theory describes the interactions between two players and pay-off from winning, losing, or compromising. In present study, Mycobacterium tuberculosis (Mtb)-host were used as an example for application of game to describe predict different outcomes Mtb-infection introducing target molecules use in protection therapy.The gene expression eight main markers (CCR1, CCR2, IDO, Tbet, TGFβ, iNOS, MMP3, MMP9) host response three Mtb virulence factors (Ag85B, CFP-10, ESAT-6) assessed...

10.22038/ijbms.2021.55471.12410 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2021-10-01

We report a 69-years-old Iranian HIV negative male patient, with long-standing pulmonary tuberculosis (eleven years) co-infected non-tuberculosis mycobacteria. Despite of initiation first line anti-tuberculosis therapy after diagnosis the patient poorly respond because low compliance anti-TB treatment. After several incomplete treatments smear was still positive and thus drug susceptibility tests were performed on isolated organism which revealed that organisms resistant not only against...

10.1016/j.rmcr.2014.11.006 article EN cc-by-nc-nd Respiratory Medicine Case Reports 2014-12-16

Most of the introduced susceptibility methods Mycobacterium tuberculosis have some disadvantages for screening. Therefore, selection assay evaluating candidate agents must be determined case by case. In this study, we evaluated validity a modified broth dilution-based in comparison to gold standard proportional method microbial sensitivity test new lipophilic compounds as antitubercular agents. The in-vitro susceptibilities 114 M. strains were separately tested against isoniazid and two...

10.1016/j.jctube.2016.01.001 article EN cc-by-nc-nd Journal of Clinical Tuberculosis and Other Mycobacterial Diseases 2016-02-13
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