- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Monoclonal and Polyclonal Antibodies Research
- Dermatology and Skin Diseases
- Advanced biosensing and bioanalysis techniques
- Transgenic Plants and Applications
- Immunotherapy and Immune Responses
- Contact Dermatitis and Allergies
- Viral Infectious Diseases and Gene Expression in Insects
- Psoriasis: Treatment and Pathogenesis
- Tuberculosis Research and Epidemiology
- RNA Interference and Gene Delivery
- Diet, Metabolism, and Disease
- Toxin Mechanisms and Immunotoxins
- Protein purification and stability
- Innovations in Medical Education
- Bacteriophages and microbial interactions
- Plant Reproductive Biology
- vaccines and immunoinformatics approaches
- Mycobacterium research and diagnosis
- Biochemical and Structural Characterization
- Biosensors and Analytical Detection
- Dietary Effects on Health
- IL-33, ST2, and ILC Pathways
Mashhad University of Medical Sciences
2016-2025
ABSTRACT Background The protective effect of a healthy diet against chronic diseases has been confirmed in several primary studies. This study identifies the dominant food patterns using factor analysis and determining its relationship with metabolic syndrome female employees participating Persian cohort study. Methods Female participants (based on National Cholesterol Education Program (NCEP ATP III) were studied cross‐sectional design. Demographic, clinical anthropometric information...
Gold nanoparticles (GNPs) have previously been suggested as appropriate carriers for allergen-specific immunotherapy (AIT). In this study, we assessed efficacy of GNPs and dendritic cells (DC)-specific aptamer-modified (Apts-GNP) epicutaneous (EPIT) in the case pollen allergen extracts containing a variety allergenic non-allergenic components. BALB/c mice were sensitized to total protein extract Platanus orientalis epicutaneously treated different groups either with free P. extract, naked...
Background The rapid uptake of antigens by antigen-presenting cells (APCs) and their migration to draining lymph nodes in the initial hours after antigen administration epicutaneous allergen specific immunotherapy (EPIT) prompted us investigate whether topical allergens without patch application could alleviate allergy pollen-sensitized mice. We evaluated immunotherapeutic effect topically administering hydrogel-based Gold nanoparticles (AuNPs) loaded with a total extract Platanus orientalis...
Smad ubiquitination regulatory factor 2 (Smurf2) consists of multiple WW domains which can interact with Smad7 molecule and inhibit signaling transforming growth factor-beta (TGF-β) cytokine. Arginase I (ArgI) is one the main products TGF-β that plays important roles in tumor escape airway tissue fibrosis remodeling asthma. In this study, effects TAT fused to WW2/WW3 (TAT-WW2/WW3) recombinant protein on ArgI gene expression were evaluated J774A.1 cell culture. For purpose, interaction...
Tuberculosis is a well-known infectious disease in human beings and domestic animals since ancient times. Tuberculin skin test as the only indicator of latent infection with Mycobacterium tuberculosis has low specificity sensitivity value. This also cannot distinguish between bovis BCG vaccination, or exposure to environmental mycobacteria. Recent identification RD1 region M. provides new opportunity for development novel diagnostic tools. The purpose this study was clone express 10-kda...