- Paraquat toxicity studies and treatments
- Saffron Plant Research Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Ginger and Zingiberaceae research
- Curcumin's Biomedical Applications
- Asthma and respiratory diseases
- Peroxisome Proliferator-Activated Receptors
- Nigella sativa pharmacological applications
- Garlic and Onion Studies
- Pesticide Exposure and Toxicity
- Flavonoids in Medical Research
- Respiratory and Cough-Related Research
- Pharmacological Effects of Medicinal Plants
- Phytochemical and Pharmacological Studies
- Genomics, phytochemicals, and oxidative stress
- Fungal Plant Pathogen Control
- Brucella: diagnosis, epidemiology, treatment
- Phagocytosis and Immune Regulation
- Therapeutic Uses of Natural Elements
- Selenium in Biological Systems
- Biological Activity of Diterpenoids and Biflavonoids
- Neurological Disorders and Treatments
- Ginseng Biological Effects and Applications
- Polydiacetylene-based materials and applications
- Gout, Hyperuricemia, Uric Acid
Mashhad University of Medical Sciences
2019-2024
University of Torbat Heydarieh
2024
L. was used for the treatment of a wide range disorders in traditional medicine. Due to extensive protective and properties
Postoperative peritoneal adhesions are considered the major complication following abdominal surgeries. The primary clinical complications of adhesion intestinal obstruction, infertility, pelvic pain, and postoperative mortality. In this study, regarding anti-inflammatory antioxidant activities Crocus sativus, we aimed to evaluate effects sativus on prevention postsurgical-induced adhesion. Male Wistar-Albino rats were used investigate preventive C. extract (0.5%, 0.25% 0.125% w/v) against...
Objectives: The effects of hydroalcoholic extract Zataria multiflora (Z. multiflora) on memory changes, as well lung injury due to inhaled paraqut (PQ) in rat, were examined.Method: Control group rat with saline aerosol administration, PQ groups (27 and 54 mg/m3) treated two doses the (200 800 mg/kg/day) dexamethasone (0.03 studied. Shuttle box Morris Water Maze (MWM) tests carried out oxidant, anti-oxidant markers, total differential white blood cell (WBC) counts cytokine levels...
Control rats were exposed to saline aerosol, two groups paraquat (PQ), 27 (PQ-L) and 54 (PQ-H) mg/m
Comparative effect of Curcuma longa (C. longa) ethanolic extract and curcumin on paraquat (PQ)-induced systemic lung oxidative stress inflammation were evaluated in the present study.Control animals exposed to normal saline PQ group 54 mg/m3 aerosols (8 times, each time for 30 min). Treatment groups treated with 150 600 mg/kg/day C. longa, or 120 after exposure period 16 days. Total differential white blood cells (WBC) markers measured both bronchoalveolar lavage (BALF) at end study.Total...
Paraquat (PQ) is an herbicide toxin that induces injury in different organs. The anti‐inflammatory and antioxidant effects of carvacrol were reported previously. pioglitazone (Pio) alone their combination on inhaled PQ‐induced systemic lung oxidative stress inflammation as well behavioral changes examined rats. In this study, animals exposed to saline (control [Ctrl]) or PQ (PQ groups) aerosols. PQ‐exposed treated with 0.03 mg/kg/day dexamethasone (Dexa), 20 80 (C‐L C‐H), 5 Pio, Pio+C‐L for...
The effects of Zataria multiflora (Z. multiflora) and pioglitazone (a PPAR-γ agonist) alone in combination, on systemic inflammation oxidative stress induced by inhaled paraquat (PQ) as a herbicide, which rats, were examined. Rats exposed to (1) saline (control) (2) 54 mg/m3 PQ aerosols (8 times, every other day, each time for 30 min) without treatment or treated with (3 4) two doses Z. (200 800 mg/kg/day), (5 6) 10 (7) low <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mi>Z</mi>...
Anti-inflammatory, antioxidant, and immunomodulatory effects of thymoquinone (TQ) have been shown. The TQ on lipopolysaccharide- (LPS-) induced inflammation pathological changes in rats’ lung were investigated this study. Four groups rats included (1) control (saline treated); (2) LPS (treated with 1 mg/kg/day i.p. for two weeks); (3 4) 5 or 10 mg/kg 30 min prior to administration. Total differential WBC counts the blood bronchoalveolar fluid (BALF), TGF-β1, INF-γ, PGE2, IL-4 levels BALF...
The effects of
The effects of PPAR-γ agonist alone and in combination with carvacrol
Abstract Exposed rats to normal saline and paraquat (PQ) aerosol as control PQ group, exposed treated with 20 80 mg/kg/day carvacrol, 5 10 pioglitazone, low dose of pioglitazone + carvacrol 0.03 dexamethasone (Dexa) for 16 days after the end exposure were studied (n = 6 in each group). Lung pathological changes, tracheal responsiveness methacholine ovalbumin (OVA) well transforming growth factor beta (TGF-β) interleukin (IL)-6 level lung tissue homogenize TGF-β, IL-6, oxidant antioxidant...
Whilst the prevalence and severity of asthma influenced by environmental factors, effect parental smoking on status their children was examined.Ninety asthmatic children, 32 with smoker 58 non-smoker parents (baseline age, 8.5 ± 3.5 8.2 3.3 respectively) were studies in two sessions 3 years apart evaluating respiratory symptoms (RS) severity, various drugs used, pulmonary function tests (PFT) including forced vital capacity; volume first second, peak expiratory flow; maximum low at 75, 50...