A5021067253- Viral-associated cancers and disorders
- Nigella sativa pharmacological applications
- Immunotherapy and Immune Responses
- Ginger and Zingiberaceae research
- Breast Cancer Treatment Studies
- Cancer Immunotherapy and Biomarkers
- Paraquat toxicity studies and treatments
- Cancer Cells and Metastasis
- Radiomics and Machine Learning in Medical Imaging
- Heme Oxygenase-1 and Carbon Monoxide
- Ear and Head Tumors
- Lung Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Chemotherapy-induced organ toxicity mitigation
- Neuroscience of respiration and sleep
- Curcumin's Biomedical Applications
- Peptidase Inhibition and Analysis
- Neonatal Respiratory Health Research
- Inflammatory mediators and NSAID effects
- Colorectal Cancer Surgical Treatments
- AI in cancer detection
- Colorectal Cancer Screening and Detection
- Fatty Acid Research and Health
- Kidney Stones and Urolithiasis Treatments
- Breast Lesions and Carcinomas
Mashhad University of Medical Sciences
2016-2025
Ghaem Hospital
2011-2025
SRM Institute of Science and Technology
2023
Apollo Proton Cancer Centre
2022
Rush University Medical Center
2018
Columbia College - Missouri
2018
Bapuji Dental College and Hospital
2014
Emam Reza Hospital
2007
Ocimum species (Lamiaceae) has been traditionally used for treatment of upper respiratory tract infections, bronchitis, coughs, sore throat, and wound healing. The Immunomodulatory anti-inflammatory effects hydro-ethanolic extract basilicum (O. basilicum) leaves was examined in ovalbumin sensitized animals.Wistar rats were divided to six groups; non-sensitized, ovalbumin, treated with dexamethasone (1.25 μg/mL), O. (0.75, 1.50 3.00 mg/mL) drinking water 21 days. levels interleukin 4 (IL-4),...
Nitric oxide is a mediator of potential importance in numerous physiological and inflammatory processes the lung. Aminoguanidine (AG) has been shown to have anti-inflammation radical scavenging properties. This study aimed investigate effects AG, an iNOS inhibitor, on lipopolysaccharide (LPS)-induced systemic lung inflammation rats. Male Wistar rats were divided into control, LPS (1 mg/kg/day i.p.), groups treated with AG 50, 100 or 150 i.p. for five weeks. Total nitrite concentration, total...
The effects of Zataria multiflora (Z. multiflora) and its constituent, carvacrol, in guinea pigs model chronic obstructive pulmonary disease (COPD) were examined. Animals divided into control, COPD, COPD + drinking water containing three concentrations extract Z. (0.4, 0.8 1.6 mg/ml), carvacrol (60, 120 240 µg/ml) dexamethasone (50 µg/ml). was induced by exposing animals to cigarette smoke for 3 months. Emphysema as a pathological change the lung tracheal responsiveness measured (n = 5...
ABSTRACT When systematic lupus erythematosus‐like lab results (e.g., positive anti‐double‐stranded DNA antibody, low complement component 3) are inconsistent with physical findings, such as the absence of arthritis or nephritis, clinicians should consider diagnoses Wilson's disease, especially in presence abnormal liver function and elevated international normalized ratio (INR).
Abstract Aim We investigated melanoma‐associated antigen A1 (MAGE‐A1) expression in lung cancer tissues and its correlation with prognostic factors. Materials Methods In this cross‐sectional study, samples from 101 patients were obtained between 2007 2014 stained for MAGE‐A1 by immunohistochemistry. Correlation factors was assessed t test, χ 2 , Pearson’s tests. Results Eighty non‐small‐cell (NSCLC) 21 small‐cell specimens MAGE‐A1. detected more commonly adenocarcinomas expressed frequently...
Abstract Lack of pre-existing tumor infiltrated T cells resulting in resistance to programmed cell death protein 1 (PD-1) blockade therapies can be solved by combining with anti-cancer vaccines and CpG-ODN increasing expansion infiltration. Therefore, we prepared an ex vivo dendritic cell-based (DC) vaccine pulsed a low dose either liposomal or non-liposomal gp100 antigen (2.8 µg) plus (800 ng) formulations evaluated its anti-tumor activity combination anti-PD-1 therapy. Our results showed...
Anti-inflammatory, antioxidant, and immunomodulatory effects of thymoquinone (TQ) have been shown. The TQ on lipopolysaccharide- (LPS-) induced inflammation pathological changes in rats’ lung were investigated this study. Four groups rats included (1) control (saline treated); (2) LPS (treated with 1 mg/kg/day i.p. for two weeks); (3 4) 5 or 10 mg/kg 30 min prior to administration. Total differential WBC counts the blood bronchoalveolar fluid (BALF), TGF-β1, INF-γ, PGE2, IL-4 levels BALF...
Cisplatin is one of the important antineoplastic drugs. Its clinical use has been restricted due to severe kidney toxicity. Nigella sativa (N. sativa) an herbaceous plant with many pharmacologic effects. In present study, we evaluated protective effects aqueous-ethanolic extract N. and Vitamin E on cisplatin-induced nephrotoxicity in rats. Eighty male rats were divided into eight groups: control, cisplatin (6 mg/kg; ip), preventive (100 mg/kg), (100,200 + treatment E, (100, 200 mg/kg)....
Microsatellite instability in sporadic colorectal can-colorectal cancer patients was assessed, and the clinicopathological associations were evaluated northeastern Iran, which is a high-risk region for gastrointestinal malignancies.Microsatellite (MSI) sta-status of tumoral tissue, compared to normal assessed with ©FUNPEC-RP www.funpecrp.com.brGenetics Molecular Research 10 (4): 3520-3529 (2011) MSI Iran 3521 standard panel markers on paraffin-embedded surgically resected tissues from 67...
Purpose: As an angiotensin converting enzyme (ACE) inhibitor, the effects of captopril on inflammation has been previously examined. Captopril shown to have anti-inflammatory and antioxidant effects. Imbalance in oxidant/antioxidant system is one major causes inflammation. In present study, total differential white blood cells (WBC), oxidative stress andlung histopathological changes produced by lipopolysaccharide (LPS) were investigated rat. Materials Method: The rats divided into: control...
Effect of alpha-linolenic acid (ALA) against ovalbumin (OVA)-induced inflammation, oxidant/antioxidant imbalance and pathological features was examined in rat.Total differential WBC count levels BALF (bronchoalveolar lavage fluid) as well lung were investigated five groups rats including controls (group C), sensitized with OVA S) S treated either ALA (0.2 0.4 mg/ml) or dexamethasone.As compared to group C, OVA-sensitized rats, increases counts, oxidant biomarkers most scores observed while...