The purpose of this study was to investigate the clinical efficacy antibiotic-loaded bone cement (ALBC) combined with Negative pressure wound therapy (NPWT) aspiration technique in treatment multidrug-resistant diabetic foot ulcers (MDRO-DFUs). A retrospective analysis data 80 patients MDROs-DFU who were used Vacuum sealing drainage (VSD) as NPWT excipient and met inclusion criteria from January 2019 2024 at our hospital. Patients divided into an experimental group a control group, 40 cases...

Perception module of Autonomous vehicles (AVs) are increasingly susceptible to be attacked, which exploit vulnerabilities in neural networks through adversarial inputs, thereby compromising the AI safety. Some researches focus on creating covert samples, but existing global noise techniques detectable and difficult deceive human visual system. This paper introduces a novel attack method, AdvSwap, creatively utilizes wavelet-based high-frequency information swapping generate samples fool...

Surface characteristics of and in vitro behavior osteoblast-like cells on titanium with nanotopography prepared by high-energy shot peening Zhennan Deng,1,2 Baodi Yin,1 Weihong Li,1 Jinsong Liu,1 Jingyuan Yang,1 Tieli Zheng,1 Dafeng Zhang,1 Haiyang Yu,2 Xiaoguang Liu,3 Jianfeng Ma1 1School Hospital Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic China; 2State Key Laboratory Oral Diseases, West China 3National Engineering Research Center for Biomaterials, Sichuan...

Polyetherketoneketone (PEKK), a high-performance thermoplastic special engineering material, maintains bone-like mechanical properties and has received considerable attention in the biomedical field. The 3D printing technique enables production of porous scaffolds with honeycomb structure featuring precisely controlled pore size, porosity interconnectivity, which holds significant potential for applications tissue engineering. ideal architecture PEKK yet to be elucidated. Porous five sizes...

Abstract Objective This article describes a novel 3D‐printed template armed with interproximal matrices to isolate contact areas and guide injectable resin composite for consecutive closure of multiple diastema. Clinical Considerations Among several treatment options proposed diastema closure, direct is noninvasive easy repair. The “composite injection technique” has been introduced improve time efficiency reduce technique sensitivity clinicians. However, in the case diastema, overflow...

A novel scaffold with large dimension of 3-4 cm in length and 1-1.5 diameter was designed fabricated for engineering bone tissue vivo. The constructed by filling hydroxyapatite (HA) spherules into a porous HA tube. were prepared chitin sol emulsification oil gelation situ, their sizes can be controlled parameters such as stirring rate temperature. Accumulation the formed interconnected pores scaffold, porosity microstructure varying size miroporous structure spherules. Porous tube coated...

Biodegradable and bioactive scaffolds with interconnected macroporous structures, suitable biodegradability, adequate mechanical property, excellent biocompatibility have drawn increasing attention in bone tissue engineering. Hence, this work, porous hydroxyapatite whisker-reinforced poly(L-lactide) (HA-w/PLLA) composite different ratios of HA PLLA were successfully developed through compression molding particle leaching. The microstructure, vitro mineralization, cytocompatibility,...

To explore the relationship between C2 slope with sagittal parameters and clinical function of degenerative cervical kyphosis (DCK).A retrospective analysis 127 patients spondylosis treated in our spinal deformity center from January 2019 to June 2022. Patients were categorized into two groups compared based on C2-7 angle (C2-7 ≥ 5° as group, < lordosis group). Pearson correlation or Spearman was used analyze C2S conventional radiological health -related quality-of-life (HRQOL) outcomes...

At present, the commonly used clinical protocols of oral cosmetic restoration are mostly based on aesthetic indexes proposed by Western developed countries (referred to as aesthetics), which different from unique Chinese people aesthetics). In design schemes and evaluation effects, these differences have a large or small effect doctor-patient-technology triad. Improper handling could directly weaken cooperation efficiency three parties, reduce patient satisfaction, even lead medical disputes...

Abstract Background Poor neurological recovery in patients after anterior cervical discectomy and fusion has been frequently reported; however, no study analyzed the preoperative imaging characteristics of to investigate factors affecting surgical prognosis. The purpose this was that affect their influence on poor neurologic fusion. Methods We retrospectively clinical data 89 who met criteria for treatment single-level spondylotic myelopathy evaluated patients’ based rate Japanese...

Abstract Objective This article describes a digital workflow using virtual enamel evaluation and stereolithographic template for accurate tooth preparation complex exogenous dental erosion. Clinical Considerations A 22‐year‐old man with different degrees of defects on the labial surface in esthetic area was diagnosed as The residual undamaged depth defect were measured analyzed accurately by creating patient based pretreatment data. According to conditions defect, treatment plans porcelain...

Cervical stiffness, coronal imbalance and limited hip movement all play crucial roles in designing the corrective surgery for ankylosing spondylitis-related thoracolumbar kyphosis (AS-TLK). However, a comprehensive classification tailored strategies directing clinical work are lacking. This study aims to investigate types surgical AS-TLK that consider cervical involvement as key factors.25 consecutive patients were divided into three according their accompanying features: Type I: with...

In Brief Study Design. Retrospective clinical case series. Objective. To report the technique and results of posterior extrapleural intervertebral space release (PEISR) combined with wedge osteotomy (WO) for treatment severe rigid scoliosis. Summary Background Data. Conventional surgical correction techniques scoliosis include anterior instrumentation fusion vertebral column resection. Methods. Between 2004 2009, 18 patients underwent PEISR WO at a single institution. The indications were...