A5002463007- Protein purification and stability
- Hormonal and reproductive studies
- Additive Manufacturing Materials and Processes
- Welding Techniques and Residual Stresses
- Monoclonal and Polyclonal Antibodies Research
- Microfluidic and Capillary Electrophoresis Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Drug Solubulity and Delivery Systems
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Pharmacological Effects and Assays
- Pesticide Residue Analysis and Safety
- Microfluidic and Bio-sensing Technologies
- Renal function and acid-base balance
- Vascular Procedures and Complications
- Biosimilars and Bioanalytical Methods
- Peripheral Artery Disease Management
- Veterinary Equine Medical Research
- Hydraulic and Pneumatic Systems
- Advanced Aircraft Design and Technologies
- Advanced Chemical Sensor Technologies
- Spacecraft Design and Technology
- CAR-T cell therapy research
- Tendon Structure and Treatment
- Ruminant Nutrition and Digestive Physiology
Johns Hopkins University Applied Physics Laboratory
2021-2023
Roche (Switzerland)
2009-2018
Institute for Sports Medicine
1995-2007
West Texas A&M University
2001
University of Oregon
1966
Massachusetts Institute of Technology
1936
The degradation of proteins by asparagine deamidation and aspartate isomerization is one several chemical pathways for recombinant antibodies. In this study, we have identified two solvent accessible sites (light chain aspartate-56 heavy aspartate-99/101) in the complementary-determining regions a IgG1 antibody susceptible to under elevated temperature conditions. For both hot-spots, degree was found be significantly higher than asparagine-(387, 392, 393) conserved CH3 region, which has been...
Since the original report (1) on transluminal recanalization of arteriosclerotic obstructions, method has been used a total 113 times in 74 different patients from January 1964 to September 1965. Treated vessels include iliac, popliteal, and tibial arteries, as well superficial deep femoral arteries. In this progress report, particular attention will be directed problems encountered, current criteria for case selection, areas future promise. Rationale Method Reduced fundamentals, technic...
IN THIS paper certain graphical conventions and their application to the solution of problems in stability vibration are described. While method is essentially a trial error one, it suggests many cases analytical approximations for frequency effective damping which will be quite acceptable practice, particularly since degree can estimated. This especially true longitudinal motion airplane, typical example worked out demonstration purposes. Analytical expressions period derived from reasoning...