- Histiocytic Disorders and Treatments
- Tuberous Sclerosis Complex Research
- Tumors and Oncological Cases
- Vascular Tumors and Angiosarcomas
- Pressure Ulcer Prevention and Management
- Surgical site infection prevention
- Cancer and Skin Lesions
- Wound Healing and Treatments
- Polyomavirus and related diseases
Hospital Universitario Doctor Peset
2019-2025
Topical rapamycin is the pharmacological treatment of choice for facial angiofibromas in rare tuberous sclerosis disease. A new, more advanced, and complex formula was developed our pharmacy service: 0.4% liposomal formulation, with better organoleptic characteristics a favorable release profile active ingredient. The purpose this study to evaluate effectiveness safety topical injuries This an observational, prospective, multicenter study. Effectiveness evaluated mainly through Facial...
Abstract Introduction Topical rapamycin has been established as an effective and safe therapy for facial angiofibromas in tuberous sclerosis. Different formulations have tested this skin disease, most using ointment a vehicle. Purpose To improve the classical formulation of topical to determine validity period proposed options based on chemical, physical, microbiological stability studies. Methods Four different 0.4% were prepared (ointment, emulsion, gel, liposomes). The studies each over...
Topical rapamycin is the pharmacological treatment of choice for facial angiofibromas in rare tuberous sclerosis disease. A new, more advanced, and complex formula was developed our pharmacy service: 0.4% liposomal formulation, with better organoleptic characteristics a favorable release profile active ingredient. The purpose this study to evaluate effectiveness safety topical injuries This an observational, prospective, multicenter study. Effectiveness evaluated mainly through severity...
Introduction: topical rapamycin has been established as an effective and safe therapy for facial angiofibromas in tuberous sclerosis. Different formulations have tested this skin disease, most using ointment a vehicle. Purpose: to improve the classical formulation of determine validity period proposed options based on chemical, physical microbiological stability studies. Methods: four different 0.4% were prepared (ointment, emulsion, gel liposomes). The studies each were: chemical...