A5049641317- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Nasal Surgery and Airway Studies
- Olfactory and Sensory Function Studies
- Allergic Rhinitis and Sensitization
- Oral and Maxillofacial Pathology
- Advanced Chemical Sensor Technologies
- Otitis Media and Relapsing Polychondritis
- Biochemical Analysis and Sensing Techniques
- Infectious Diseases and Mycology
- Asthma and respiratory diseases
- Bone Tumor Diagnosis and Treatments
- Congenital Ear and Nasal Anomalies
- Tracheal and airway disorders
- Vascular Anomalies and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Obstructive Sleep Apnea Research
- Teratomas and Epidermoid Cysts
- Cerebral Venous Sinus Thrombosis
- Tumors and Oncological Cases
- Sarcoma Diagnosis and Treatment
- Cystic Fibrosis Research Advances
- Long-Term Effects of COVID-19
- Soft tissue tumor case studies
Universidade de São Paulo
2016-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2010-2024
Hospital Universitário da Universidade de São Paulo
2002-2023
Instituto Butantan
2023
Hospital das Clínicas da Universidade Federal de Pernambuco
2021
John Wiley & Sons (United States)
2016
Universidad San Pedro
2007
Hospital Socor
2006
Hospital São Paulo
2001-2006
Centro Universitário das Faculdades Metropolitanas Unidas
2006
The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of similar evidence based position papers published in 2005 2007. document contains chapters definitions classification, we now also proposed for difficult to treat rhinosinusitis, control disease better rhinosinusitis children. More emphasis placed diagnosis treatment acute rhinosinusitis. Throughout terms chronic without nasal polyps (CRSsNP) with (CRSwNP) are used further point out differences...
EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012.A summary for otorhinolaryngologists. no immunosuppressants IV D saline irrigation Ib, data in single use yes symptomatic relief topical antibiotics anti-IL-5 unclear phytotherapy decongestant / oral mucolytics antihistamine allergic patients antimycotics -topical Ia (-) ** A(-) -systemic Ib (-)# $ anti leukotrienes anti-IgE * Some of these studies also included with CRS polyps.% short term shows one positive negative...
Chronic rhinosinusitis (CRS) is a public health problem that has significant socio-economic impact. Moreover, the complexity of this disease due to its heterogeneous nature based on underlying pathophysiology - leading different variants further complicates our understanding and directions for most appropriate targeted treatment strategies. Several International/national guidelines/position papers and/or consensus documents are available present current knowledge strategies CRS. Yet there...
Glucocorticoids (GCs) are considered drugs of choice for treating nasal polyps (NPs). However, a subset patients shows limited clinical response even to high doses GCs. Altered expression glucocorticoid receptors (GRs), namely GR-alpha; and GR-beta;, is potential mechanism underlying GC insensitivity. GCs modulate the several cytokines, including transforming growth factor-beta (TGF-beta), which may contribute cellular proliferation in NPs. The study investigates some biomolecular features...
Our study aimed to measure the percentage of reported olfactory or taste losses and their severity, recovery time, association with other features in a large cohort patients COVID-19.Prospective survey.Quaternary medical center online survey.The perceived chemosensory capacities 655 confirmed COVID-19 were assessed 11-point category rating scales (0, no function; 10, normal function). Patients contacted hospital, by phone calls, internet regarding ability smell taste, 143 interviewed 1 4...
Introduction:Studies designed to investigate chronic rhinosinusitis (CRS) epidemiology play an important role assess population's distribution and risk factors result in the development promotion of public health policies.Method: This study design is a survey carried out with complex two-stage cluster sampling plan.Personal interviews were 2,003 individuals.The questionnaire included epidemiological criteria for CRS.Demographic data, history physician-diagnosed respiratory diseases (asthma,...
BACKGROUND: The Nasal Obstruction Symptom Evaluation (NOSE) instrument is a disease-specific questionnaire for assessing the outcome of an intervention in nasal obstruction trials. This only available English language and cross-culturally valid questionnaires are very important all research, including obstruction. aim current study was to reproduce cross-cultural adaptation process NOSE Portuguese (NOSE-p). METHODOLOGY/PRINCIPAL: Cross-cultural validation were divided into two stages. Stage...
It is well established that olfactory dysfunction has significant implications for safety, nutrition, and quality of life. The more reliable standardized tests function, such as the University Pennsylvania Smell Identification Test (UPSIT), assess odor identification ability. Unfortunately, cultural factors can influence tests, a number odors are not universally recognized. In this study, Portuguese language version UPSIT was administered to an age- sex-stratified prospective sample 1820...
Biologics targeting type 2 inflammation have revolutionized the way we treat patients with Chronic Rhinosinusitis Nasal Polyps (CRSwNP). Particularly in severe and difficult-to-control cases, these drugs provided a new reality for patients, allowing effective safe treatment of extensive diseases that were not completely managed typical strategy surgery topical medications. The experience achieved approval medications by ANVISA use CRSwNP knowledge obtained regarding outcomes, adverse...
To describe the anatomy of sphenopalatine foramen (SPF) region and possible anatomical variations.Prospective study accomplished from September, 2006, to January, 2007.The 61 cadavers were carefully dissected. Presence ethmoidal crest, location accessory foramens, number arterial branches emerging through foramens observed. Data analyzed in relation gender, racial group, symmetry cadaver. Prediction presence was evaluated.Mixed race prevailed 122 nasal fossae dissected (75% males). Ethmoidal...
Nasal obstruction is a common complaint in the population. When caused by deviated nasal septum, septoplasty procedure of choice for treating these patients. NOSE tool assessing disease-specific quality life related to obstruction.To assess impact on patients with secondary septum based quality-of-life questionnaire.Prospective.Patients undergoing with/without turbinectomy after no clinical improvement medical treatment were assessed questionnaire before and 3 months surgery. We evaluated...
Computational fluid dynamics (CFD) allows quantitative assessment of transport phenomena in the human nasal cavity, including heat exchange, moisture transport, odorant uptake olfactory cleft, and regional delivery pharmaceutical aerosols. The first step when applying CFD to investigate airflow is create a 3-dimensional reconstruction anatomy from computed tomography (CT) scans or magnetic resonance images (MRI). However, method identify exact location air-tissue boundary CT MRI currently...
Abstract Introduction Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a chronic inflammatory condition of the paranasal sinuses that mainly associated type-2 inflammation. Immunoglobulin E (IgE) and eosinophils in blood tissue have been suggested as biomarkers for prognosis severity CRSwNP well indications biological treatment. Objective The present study aims to assess relationships between IgE concentration, eosinophil count, polyp count patients. Methods retrospective. Nasal...
To present our experience with endoscopic ligature of the sphenopalatine artery in treatment severe posterior epistaxis patients who had previously undergone conservative procedures.Eleven were treated during a 25-month period an artery. The basic principle surgical technique is to identify branches through endonasal approach and apply titanium clip under direct vision.The was performed unilaterally 10 bilaterally 1 patient, total 12 ligatures. It possible all cases successful outcome using...
The University of Pennsylvania Smell Identification Test, a test olfactory function that is widely used by otolaryngologists, geriatricians, and neurologists, has been translated into more than dozen languages.In some instances, cultural socioeconomic factors have necessitated changes in the odorant items or response alternatives to make scores congruent with North American norms.The objective this study was compare performance Brazilian subjects on new Portuguese language version Test their...
This study aimed to assess clinical outcomes of long-term low-dose oral doxycycline therapy in difficult-to-treat chronic rhinosinusitis with polyps (CRSwNP).This was a prospective, open-label 60 patients CRSwNP who had undergone endoscopic sinus surgery. Patients were divided into two groups: 28 received nasal steroids, saline irrigation, and (200 mg on the first day, followed by 100 once daily) for 12 weeks, while 30 only steroids irrigation. The main outcome measure an adequate effect...