A5003605533- Clinical Nutrition and Gastroenterology
- Gastric Cancer Management and Outcomes
- Burn Injury Management and Outcomes
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Thermal Regulation in Medicine
- Abdominal Surgery and Complications
- Reproductive System and Pregnancy
- Infant Nutrition and Health
- Enhanced Recovery After Surgery
- Helicobacter pylori-related gastroenterology studies
- Ovarian function and disorders
- Tracheal and airway disorders
- Spaceflight effects on biology
- Autophagy in Disease and Therapy
- Stress Responses and Cortisol
- Cleft Lip and Palate Research
- Tryptophan and brain disorders
- Electrolyte and hormonal disorders
- Ginger and Zingiberaceae research
- Electrospun Nanofibers in Biomedical Applications
- Renal Diseases and Glomerulopathies
- Neurotransmitter Receptor Influence on Behavior
- Turtle Biology and Conservation
- Tea Polyphenols and Effects
Shenyang 242 Hospital
2018-2025
Nanjing Normal University
2025
Shandong University of Traditional Chinese Medicine
2020-2022
Wuhan Polytechnic University
2021
Center of Hubei Cooperative Innovation for Emissions Trading System
2021
Fourth Affiliated Hospital of Guangxi Medical University
2019
Fifth Tianjin Central Hospital
2016
Beihua University
2016
General Hospital of Shenyang Military Region
2007-2015
Peking Union Medical College Hospital
2015
MicroRNA (miR)-421 plays a key role in cancer progression. It has been reported that circulating miR-421may be potential tumor marker for the diagnosis of several cancers. However, miR-421 plasma as biomarker precancerous gastric lesions (Pre) and early-stage (GC) remains poorly understood. In this study, we investigated novel detection (GC).The miRNA content was determined by quantitative real-time polymerase chain reaction (qRT-PCR). MiR-421 all subjects normalized endogenous (miR-16). The...
Mouse strain differences in immobility and sensitivity to antidepressants have been observed the forced swimming test (FST) tail suspension (TST). However, neurotransmitter systems neural substrates that contribute these remain unknown. To investigate role of hippocampal serotonin transporter (5-HTT), we measured baseline responses fluoxetine (FLX) FST TST male CD-1, C57BL/6, DBA BALB/c mice. We time, with CD-1 mice showing longest shortest. In contrast, showed highest FLX, whereas C57BL/6...
Background Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder with complex pathophysiology, affecting various aspects of women’s health. Despite its widespread impact, the molecular basis and immunological PCOS remain insufficiently understood, limiting effective diagnosis treatment strategies. Objective This study aims to elucidate landscape by integrating gene expression profiles from healthy PCOS-affected ovaries using both bulk single-cell omics data, goal constructing...
The intensification of global warming could precipitate the widespread dissemination opportunistic pathogens, exerting a bidirectional strain on wildlife populations and potentially hastening process species extinction. In this study, we integrated indicators from peripheral blood single-cell transcriptome, behavior, physiological indices in Chinese soft-shelled turtles (Pelodiscus sinensis) to explore impact dual stress caused by bacterial infections and/or heatwaves turtles. Turtles were...
Theaflavins, the major black tea polyphenols, have been reported to exhibit promising antitumor activities in several human cancers. However, role of theaflavins hepatocellular carcinoma (HCC) is still unknown. In this study, we found that could significantly inhibit proliferation, migration, and invasion, induce apoptosis HCC cells vitro. Furthermore, inhibited growth metastasis an orthotopic model a lung model. Immunohistochemical analyses terminal deoxynucleotidyl transferase dUTP nick...
Polycystic ovary syndrome (PCOS) seriously affects the fertility and health of women childbearing age. We look forward to finding potential biomarkers for PCOS that can aid clinical diagnosis.We acquired normal granulosa cell (GC) expression profiles from Gene Expression Omnibus (GEO) database. After data preprocessing, differentially expressed genes (DEGs) were screened by limma package, Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) enrichment analysis Set Enrichment Analysis (GSEA)...
ABSTRACT Stress influences the development of depression, and depression is associated with structural functional changes in hippocampus. The current study sought to determine whether chronic corticosteroid (CORT) treatment serotonin transporter (5‐HTT) protein expression function CA1, CA3, dentate gyrus (DG) subregions Male CD‐1 mice were subcutaneously injected CORT at a dose 20 mg/kg once daily for 3 weeks. Behavioral state was assessed using sucrose preference, physical coat, forced...
The aim of the present study was to investigate effects enteral nutrition (EN) with parenteral glutamine (GLN) supplementation on inflammatory response, lymphatic organ apoptosis, immunological function and survival in septic rats by caecal ligation puncture (CLP). Male were randomly assigned into two experimental groups sham CLP control ( n 10 per group). After or model programme completed, GLN concentrations plasma tissues several indices including serum Ig content, circulating lymphocyte...
The aim of the present study was to construct tissue‑engineered laryngeal cartilage with a hollow, semi‑flared shape using poly(3‑hydroxybutyrate‑co‑3‑hydroxyhexanoate) (PHBHH) scaffold. Porous PHBHH prepared and formed into shape, cell‑material composites were cultured for one week in vitro prior implantation vivo. Cells nine rabbits experimental group filled encapsulated myofascial flap‑shaping material composite situ implantation. three control treated shaping without chondrocytes....
Glaesserella parasuis causes porcine Glässer's disease and lipopolysaccharide (LPS) induces acute inflammation pathological damage. Baicalin has antioxidant, antimicrobial, anti-inflammatory functions. Long noncoding RNAs (lncRNAs) play key regulatory functions during bacterial infection. However, the role of lncRNAs in vascular dysfunction induced by a combination G. LPS systemic effect baicalin on lncRNA expression aortic endothelial cells (PAVECs) have not been investigated. In this...
Asthma is a common chronic respiratory disease characterized by wheezing and shortness of breath. Its risk factors include genetic acquired factors. The are closely related to the environment, especially cold conditions. Autophagy plays regulatory role in asthma. Therefore, we hypothesized that asthma can be controlled drug intervention at autophagy level under Xiaoqinglong decoction (XQLT) was freeze-dried. compounds freeze-dried powder were identified quantified using reference standards...
To analyze the composition and control status of chronic diseases among rural residents in a Beijing suburb district.Rural aged 35 years or older were investigated by stratified random sampling Pinggu District, Beijing. Each participant received questionnaire-based survey,physical examination,and laboratory tests including routine blood test,urine albumin creatinine ratio (ACR), liver renal function,serum lipid, fasting glucose, glycosylated hemoglobin.A total 10 385 completed all items....