Abstract Despite the growing demand for corporate environmental, social, and governance (ESG) engagement in response to global complex crisis, impacts of ESG activities market environment on firm performance have not been sufficiently investigated. This study aims explore how affect competitive moderates this relationship. The panel data regression analysis was performed investigate relationship between (specifically, capitalization as a measure market‐based profit margin return assets...

Although there has been a lot of research on the effect workforce diversity innovation performance, studies and development (R&D) team have scarce. Moreover, even previous considered R&D performances at firm level, which left relationship between inputs outputs unclear. This study aimed to investigate more precisely by examining project level. The gender, major, education diversities were project‐level measured four indicators: papers, patents, success, innovative sales. After...

The operation of an electrochemical real-time PCR system, based on intercalative binding methylene blue (MB) with dsDNA, has been demonstrated. was performed a fabricated electrode-patterned glass chip containing MB while recording the cathodic current peak by measuring square wave voltammogram (SWV). signal found to decrease increase in cycle number. This phenomenon be mainly consequence lower apparent diffusion rate MB-DNA complex (Db = 6.82 × 10−6 cm2 s−1 612 bp dsDNA) as compared that...

New drug development guarantees a very high return on success, but the success rate is extremely low. Pharmaceutical companies have attempted to use various strategies increase of development, this goal has been difficult achieve. In study, we developed model that can guide effective decision-making at planning stage new by leveraging machine learning. The Drug Development Recommendation (DDR) model, present here, hybrid for recommending and/or predicting groups suitable individual...

A label-free colorimetric method for the detection of biological thiols (biothiols) was developed. This is based on prevention photoinduced reduction auric ions (Au(III)) in presence amino acids (acting as a reducing agent) by biothiols; inhibited due to strong interaction biothiols with Au(III). In this method, sample first incubated an assay solution containing Au(III) and threonine; then exposed 254 nm UV light. For samples without biothiols, process led photoreduction followed growth...

While the cases of small and medium enterprises (SMEs) that succeeded in research development (R&D) have been relatively well known studied, there has not sufficient on R&D failure consequent costs. Based upon resource-based view, we hypothesized commercialization SME's would be more severe for smaller firms lacking resources dynamic capabilities, leading to early business closure. We analyzed 2,038 formal projects implemented by South Korean SMEs with support a public subsidy program. found...

Large teams are known to be more likely publish highly cited papers, while small better at publishing disruptive papers. However, there is a lack of adequate theoretical understanding the mechanisms by which scientific collaboration among researchers related impact their We investigated closely focusing on interaction inter-organizational diversity and team size in process formation knowledge dissemination. analyzed 12,010,102 Web Science papers examined how associated with relationship...

Red gold/blue gold: A highly convenient colorimetric method for the identification of single-nucleotide polymorphism was developed by utilizing gold nanoparticles and an allele-specific polymerase chain reaction. Its diagnostic capability successfully demonstrated correctly identifying various mutations in BRCA1 gene. Detailed facts importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available...

A label-free, colorimetric method has been developed for ultrasensitive detection of nucleic acids that is based on photoinduced silver ion (Ag+) reduction around DNA bases. The assay system capable directly detecting bacterial genomic without the need PCR amplification.

Abstract Background The recent innovation activities of global top-tier pharmaceutical companies in accordance with and regional health concerns were investigated order to identify their innovations contributing population health. Methods “Innovation activity” was defined as the number drugs for which R&D have been reported within last three years. Such measured by collecting data on drug developments classifying them developer company, phase development, therapeutic use, country...

Abstract To improve the efficiency of government-funded research and development (R&D) programs for small medium enterprises, it is necessary to make process selecting beneficiary firm objective. We aimed develop machine learning models predict performances individual R&D projects in advance, present an objective method that can be utilized project selection. trained our on data from 1771 conducted South Korea between 2011 2015. The likelihood success, commercialization, patent...

Market intelligence, which collects and analyzes market trends competitive landscape, is crucial for business success in the market. In particular, defining scope important because analysis outcomes vary depending on where boundaries are. However, this has been challenging due to difficulty scoping a number of similar products into target appropriately. To address challenge, study devised novel method acquiring reliable intelligence utilizing Sentence-RoBERTa (SRoBERTa) model, pre-trained...

A signal-on, colorimetric deoxyribonuclease I (DNase I) activity assay is developed based on the novel finding that DNase can promote photoinduced synthesis of gold nanoparticles.

Despite a long period of research on the relationship between competition and innovation, contradictory observations about their have been reported there is yet no consensus this relationship. Moreover, few studies how affected by characteristics companies participating in market. In article, we aim to examine innovation activities, particularly pharmaceutical industry, investigate moderated size age leading companies. By analyzing 8243 drug development activities competitive intensity...

In this study, we aimed to assess health research funding allocation in South Korea by analysing the relationship between government and disease burden Korea, specifically focusing on cancers.The cancer burden, measured disability-adjusted life-years (DALYs), was analysed using a linear regression method over 10-year interval. Funding information 25 types of obtained from National Science Technology Information Service portal Korea. Measures were Global Burden Disease studies. The...

Information on market size is fundamental for marketing and business decision-making. However, information mostly available at the level of industry or broad categories, which include a large number product groups. Since many companies require segmented level, especially their own products, methodology to estimate by specified group (i.e., item) required. This study proposes estimation model based measurement string similarity between names. The target items estimated calculating sales...