- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- Medical Image Segmentation Techniques
- Lung Cancer Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Radiopharmaceutical Chemistry and Applications
- Advanced Radiotherapy Techniques
- Surgical Simulation and Training
- Click Chemistry and Applications
- Advanced Vision and Imaging
- Augmented Reality Applications
- Robotics and Sensor-Based Localization
- Image Retrieval and Classification Techniques
- Alzheimer's disease research and treatments
- Cardiac Valve Diseases and Treatments
- Statistical Methods and Inference
- Soft Robotics and Applications
- Cardiovascular Function and Risk Factors
- Lung Cancer Treatments and Mutations
- Medical Imaging and Analysis
- Brain Tumor Detection and Classification
- MRI in cancer diagnosis
- Functional Brain Connectivity Studies
Siemens (United States)
2020
Siemens (United Kingdom)
2009-2018
Siemens (Germany)
2008-2015
October 6 University
2015
Siemens Healthcare (Germany)
2015
Charité - Universitätsmedizin Berlin
2015
University of Manchester
2008
Mirada Medical (United Kingdom)
2005-2007
University of Oxford
1997-2002
Science Oxford
1997-2001
Background Estimation of the risk malignancy in pulmonary nodules detected by CT is central clinical management. The use artificial intelligence (AI) offers an opportunity to improve prediction. Here we compare performance AI algorithm, lung cancer prediction convolutional neural network (LCP-CNN), with that Brock University model, recommended UK guidelines. Methods A dataset incidentally measuring 5–15 mm was collected retrospectively from three hospitals for a validation study. Ground...
The management of indeterminate pulmonary nodules (IPNs) remains challenging, resulting in invasive procedures and delays diagnosis treatment. Strategies to decrease the rate unnecessary optimize surveillance regimens are needed.
IntroductionDeep Learning has been proposed as promising tool to classify malignant nodules. Our aim was retrospectively validate our Lung Cancer Prediction Convolutional Neural Network (LCP-CNN), which trained on US screening data, an independent dataset of indeterminate nodules in European multicentre trial, rule out benign maintaining a high lung cancer sensitivity.MethodsThe LCP-CNN generate malignancy score for each nodule using CT data from the U.S. National Screening Trial (NLST), and...
Background —VDD pacing can enhance systolic function in patients with dilated cardiomyopathy and discoordinate contraction; however, identification of likely to benefit is unclear. We tested predictors responsiveness on the basis global parameters as well directly assessed mechanical dyssynchrony. Methods Results —Twenty-two DCM conduction delay were studied by cardiac catheterization a dual-sensor micromanometer measure LV aortic pressures during sinus rhythm free-wall pacing. Pacing...
Routine quantification of myocardial blood flow (MBF) requires robust and reproducible processing dynamic image series. The goal this study was to evaluate the reproducibility 3 highly automated software programs commonly used for absolute MBF reserve (stress/rest MBF) assessment with <sup>82</sup>Rb PET imaging. <b>Methods:</b> Dynamic rest stress scans were selected in 30 sequential patient studies performed at separate institutions using different 3-dimensional PET/CT scanners. All 90...
Single photon emission computed tomography (SPECT) imaging with /sup 201/Tl or 99m/Tc agent is used to assess the location extent of myocardial infarction ischemia. A method proposed decrease effect operator variability in visual quantitative interpretation scintigraphic perfusion studies. To this, patient's images (target cases) are registered automatically over a template image, utilizing nonrigid transformation. The intermediate steps are: 1) Extraction feature points both stress and rest...
Tag team: The fluoro-detagging of fluorous sulfonates by the [18F]fluoride ion was found to be an advantageous strategy for preparation various 18F-labeled prosthetic groups and known radiotracers (see picture). Fluorous solid phase extraction (FSPE) used separate excess precursor from labeled material, which suggests that traditional purification protocols such as distillation or tedious separation can avoided. Detailed facts importance specialist readers are published "Supporting...
The objective of this work is to evaluate a new concept intraoperative three-dimensional (3D) visualization system support hepatectomy. Resection Map aims provide accurate cartography for surgeons, who can therefore anticipate risks, increase their confidence and achieve safer liver resection. In an experimental prospective cohort study, ten consecutive patients admitted hepatectomy three European hospitals were selected. Liver structures (portal veins, hepatic tumours parenchyma) segmented...
We propose a new methodology, reference Standardised Uptake Value (SUVref), for reducing the quantitative variation resulting from differences in reconstruction protocol. Such that is not directly addressed by use of SUV or recently proposed PERCIST can impede comparability between positron emission tomography (PET)/CT scans. SUVref applies reconstruction-protocol-specific phantom-optimised filter to clinical PET scans purpose improving quantification. The ability this reduce variability due...
This paper presents an approach to predict the deformation of lungs and surrounding organs during respiration. The framework incorporates a computational model respiratory system, which comprises anatomical extracted from computed tomography (CT) images at end-expiration (EE), biomechanical physiology, including material behavior interactions between organs. A personalization step is performed automatically estimate patient-specific thoracic pressure, drives model. zone-wise pressure values...
Through recent development of MR techniques, it is now possible to assess regional myocardial wall function in a non-invasive way. Using tagging, space marked with planes which deform the tissue, providing markers for tracking local motion myocardium. Numerous methods reconstruct three-dimensional displacement field have been developed. The aim this article provide framework quantitatively compare performance four authors Five sets experiments are described, and their results reported....
The Staudinger ligation of phosphine-substituted thioesters with (18)F-fluoroethylazide has been successfully applied to access (18)F-labelled molecules in radiochemical yields superior 95%; the first fluorous variant a radio-ligation validated.
Intraarterial injections of small doses gadopentetate dimeglumine were combined with a fast spoiled-gradient-echo magnetic resonance (MR) sequence to obtain real-time projection angiographic images the rabbit aorta and canine coronary arteries. Arterial filling washout, as well venous perfusion phases, clearly displayed, demonstrating that arterial fluoroscopy in which an MR technique is used feasible.
Minimally invasive therapy (MIT) is one of the most important trends in modern medicine. It includes a wide range therapies videoscopic surgery and interventional radiology performed through small incisions. reduces hospital stay-time by allowing faster recovery offers substantially improved cost-effectiveness for society. However, introduction MIT has also led to new problems. The manipulation structures within body incisions dexterity tactile feedback. requires different approach than...