A5103013634- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Polyamine Metabolism and Applications
- Magnesium Alloys: Properties and Applications
- Biochemical and Molecular Research
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- RNA regulation and disease
- Corrosion Behavior and Inhibition
- Microfluidic and Capillary Electrophoresis Applications
- Biosensors and Analytical Detection
- Neuroinflammation and Neurodegeneration Mechanisms
- Microfluidic and Bio-sensing Technologies
- CRISPR and Genetic Engineering
- 3D Printing in Biomedical Research
- Bacteriophages and microbial interactions
- Aluminum Alloys Composites Properties
- Nanocluster Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- RNA and protein synthesis mechanisms
- Extracellular vesicles in disease
- Cytokine Signaling Pathways and Interactions
- Autophagy in Disease and Therapy
- Milk Quality and Mastitis in Dairy Cows
- Intracerebral and Subarachnoid Hemorrhage Research
Beijing Institute of Technology
2015-2025
Shenzhen MSU-BIT University
2024-2025
National Animal Husbandry Service
2024
Fudan University
2020
Marshall Medical Center
2020
Renji Hospital
2020
Shanghai Jiao Tong University
2020
International Islamic University, Islamabad
2020
Qingdao Agricultural University
2017-2019
State Council of the People's Republic of China
2019
Abstract Here, a facile approach for the in situ fabrication of metal sulfide (MS)‐graphene (G) nanocomposite, CdS‐G and PbS‐G, on indium−tin oxide (ITO) glass is demonstrated using simple scalable direct‐laser‐writing method ambient air. Through CO 2 laser irradiation metal‐complex‐containing polyethersulfone layer ITO glass, both crystallization laser‐induced MS (LIMS) formation graphene (LIG) are synchronously achieved one step, giving rise to MS‐G nanocomposite photoelectrode, denoted as...
Although researches until now have emphasized the influence of an oligonucleotide sequence on fluorescence oligonucleotide-stabilized silver nanoclusters (AgNCs), this has been explored as a novel ratiometric fluorescent signal transduction in work. This study builds our original discovery template-transformation phenomenon, which demonstrated that connection special DNA fragment (5'-CACCGCTTT-3') with green-emitting AgNC nucleation (GNuS, 5'-TGCCTTTTGGGGACGGATA-3') creates red-emitting...
In this work, a novel fluorescent transformation phenomenon of oligonucleotide-encapsulated silver nanoclusters (AgNCs) was demonstrated, in which green-emissive AgNCs effectively transformed to red-emissive when placed close proximity special DNA fragment (denoted as convertor here). Taking advantage catalyzed-hairpin-assembly (CHA) amplification strategy, we rationally and compatibly engineered simple sensitive AgNC-based signal strategy through the ratiometric catalyzed-assembly (RCA)...
The intrinsic features and functions of platelets mesenchymal stem cells (MSCs) indicate their great potential in the treatment intracerebral hemorrhage (ICH). However, neither them can completely overcome ICH because stealth process complex pathology ICH. Here, we fabricate hybrid for versatile highly efficient therapy by fusing MSCs with loading lysophosphatidic acid-modified PbS quantum dots (LPA-QDs). obtained LPA-QDs@FCs (FCs = fusion cells) not only inherit capabilities both but also...
Herein, direct-laser-writing of TiO2-decorated graphene on indium-tin oxide glass was demonstrated to fabricate a unique photoelectrode with rapid and stable photoelectrochemical response under visible light; this then applied in enzymatic biosensor for the sensitive detection an acetylcholinesterase inhibitor.
Abstract: Neuroinflammation has emerged as a crucial factor in the pathogenesis of Alzheimer's disease (AD), paving way for promising therapeutic interventions. Increasing evidence highlights interplay between peripheral immune system and central nervous (CNS) driving neuroinflammation, with T lymphocytes playing vital role both regulatory effector functions. Aberrant activation cells during early stages neuroinflammation perpetuates inflammatory responses by interacting CNS glial releasing...
Ionizing radiation (IR) is of clinical importance for glioblastoma therapy; however, the recurrence glioma characterized by resistance remains a therapeutic challenge. Research on irradiation-induced transcription in glioblastomas can contribute to understanding radioresistance mechanisms. In this study, using total mRNA sequencing (RNA-seq) analysis, we assayed global gene expression human cell line U251 MG at various time points after exposure growth arrest dose γ-rays. We identified 1656...
Direct-laser-writing of three-dimensional porous graphene frameworks on indium-tin-oxide glass towards the fabrication a unique electrode with outstanding electrochemical performance.
Fault diagnosis is of crucial importance to mechanical systems. To find an efficient way conducting fault for refrigeration systems, probabilistic neural network, and back-propagation network were employed diagnose seven types typical faults a 90-ton centrifugal chiller. These include system-level such as refrigerant leak/undercharge, overcharge, excess oil also component-level condenser fouling, reduced water flow, noncondensables in the refrigerant, evaporator flow. Eight major features...
Abstract After implantation of the Mg alloy in human body, adsorption plasma protein on surface will cause a series cell reactions and affect degradation alloys. Herein, vitro biological ZK60 AZ31 alloys are analyzed environment. Combined with mass spectrometry analysis type adsorbed proteins, it is shown that proteins such as fibrinogen, vitronectin, fibronectin, prothrombin prone to get than other leading promotion MG63 adhesion proliferation. The effect selected (fibrinogen, prothrombin)...
A microfluidic chip native protein electrophoresis was established to predict aggregation.
Abstract Background Loss of function mutations in the spermine synthase gene (SMS) have been reported to cause a rare X-linked intellectual disability known as Snyder-Robinson Syndrome (SRS). Besides disability, SRS is also characterized by reduced bone density, osteoporosis and facial dysmorphism. phenotypes evolve with age from childhood adulthood. Methods Whole exome sequencing was performed know causative gene/pathogenic variant. Later we confirmed pathogenic variant through Sanger...