A5102026420- Advances in Oncology and Radiotherapy
- Radiation Dose and Imaging
- Radiology practices and education
- Cardiac Imaging and Diagnostics
- Vascular anomalies and interventions
- Retinal Diseases and Treatments
- Advanced X-ray and CT Imaging
- Pediatric Urology and Nephrology Studies
- Kidney Stones and Urolithiasis Treatments
- Gastroesophageal reflux and treatments
- Aortic aneurysm repair treatments
- Urological Disorders and Treatments
- Atrial Fibrillation Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Biomedical and Engineering Education
- Venous Thromboembolism Diagnosis and Management
- Biomedical Text Mining and Ontologies
- Ureteral procedures and complications
- Retinal Imaging and Analysis
- Digital Radiography and Breast Imaging
- Aortic Disease and Treatment Approaches
- Urinary Bladder and Prostate Research
- Nuclear and radioactivity studies
- Gastrointestinal motility and disorders
King's College Hospital
1993-2024
University of Connecticut
2017
Clean Energy (United States)
2017
King's College Hospital NHS Foundation Trust
2013-2016
King's College London
2003-2016
King's College School
2016
St Peter's Hospital
2015
University of Cambridge
2013-2014
Respiratory Clinical Trials
2011
University College London
1984-1994
Neovascular age-related macular degeneration (nAMD) is a leading cause of blindness. The first-line therapy anti-vascular endothelial growth factor (anti-VEGF) agents delivered by intravitreal injection. Ionising radiation mitigates key pathogenic processes underlying nAMD, and therefore has therapeutic potential. STAR aimed to assess whether stereotactic radiotherapy (SRT) reduces the number anti-VEGF injections required, without sacrificing visual acuity.
Cerebral blood flow was measured both under conditions of normocapnia and hypercapnia in 22 diabetic patients 20 normal control subjects, using either the intravenous 133 Xe method or closely comparable inhalation method. While 19 out subjects responded appropriately to with an increase flow, eight failed respond normally, this difference being significant ( p = 0.03). Those manifesting abnormal response included young, insulin‐dependent a short duration diabetes no clinical evidence complications.
In the UK, as elsewhere, there is potential to improve how radiological challenges are addressed through improvement in, or development of, a strong radiation protection (RP) safety culture. preliminary work in two areas have been identified having influence on UK society: healthcare and nuclear industry sectors. Each has specific challenges, but with many overlapping common factors. Other sectors will benefit from further consideration.In order make meaningful comparisons between these...
The geko™ device is a single-use, battery-powered, neuromuscular electrostimulation that aims to reduce the risk of venous thromboembolism (VTE). National Institute for Health and Care Excellence (NICE) selected evaluation, invited manufacturer, Firstkind Ltd, submit clinical economic evidence. King's Technology Evaluation Centre, an External Assessment Centre (EAC) commissioned by NICE, independently assessed evidence submitted. sponsor submitted related and, in addition, included studies...
The development of pulmonary infiltrate in neutropenic patients is potentially life-threatening, and requires early diagnosis treatment. Bronchoscopic sampling an established form investigation such patients.The aim the study to determine diagnostic yield complication rate bronchoscopic with a haematological disorder presenting febrile neutropenia infiltrate.Medical records laboratory investigations were retrospectively reviewed for all who underwent flexible bronchoscopy bronchoalveolar...
A clinical diagnosis of bile acid malabsorption (BAM) can be confirmed using SeHCAT (tauroselcholic ((75)selenium) acid), a radiolabelled synthetic acid. However, while BAM the cause chronic diarrhoea, it is often overlooked as potential diagnosis. Therefore, we investigated use for in UK hospitals.A multicentre survey was conducted capturing centre and patient-level information detailing patient care-pathways, history, results, treatment with sequestrants (BAS), follow-up clinics. Eligible...
The measurement of total body water by bioelectrical impedance in a group renal patients was evaluated against the tritium dilution method. effect haemodialysis and presence peritoneal dialysate on were also investigated. correlation between two methods is r = 0.90 with residual standard deviation 3.7. differences means 3.66 which that (TBW) estimated (BEI) method may be 6.18 l (X +/- 2 SD) above or 8.38 below 3H2O BEI overestimated actual weight loss after (3.87 1.7 versus 2.43 1.8 l) but...
The standard of care for neovascular age-related macular degeneration (nAMD) involves ongoing intravitreal injections anti-angiogenic drugs targeting vascular endothelial growth factor (VEGF). most commonly used anti-VEGF are ranibizumab, bevacizumab and aflibercept. main objective the STAR trial is to determine if stereotactic radiotherapy can reduce number that patients with nAMD require.STAR a multicentre, double-masked, randomised, sham-controlled clinical trial. It evaluates new device...
The human bladder is very permeable to water. We assessed this work in the context of possible changes patients with tumours
To assess the safety and efficacy of epimacular brachytherapy (EMB) for patients with chronic, active, neovascular age-related macular degeneration (AMD).Phase 3 randomized controlled trial.Patients (n = 363) AMD already receiving intravitreal ranibizumab injections.Either pars plana vitrectomy 24-gray EMB ongoing pro re nata (PRN) 224) or PRN monotherapy 119).The coprimary outcomes, at 12 months, were number injections Early Treatment Diabetic Retinopathy Study (ETDRS) best-corrected visual...
Journal Article Chest radiography: a comparison of image quality and effective dose using four digital systems Get access A. Pascoal, Pascoal *Corresponding author: ana.pascoal@kcl.ac.uk Search for other works by this author on: Oxford Academic PubMed Google Scholar C. P. Lawinski, Lawinski Mackenzie, Mackenzie S. Tabakov, Tabakov Lewis Radiation Protection Dosimetry, Volume 114, Issue 1-3, 17 May 2005, Pages 273–277, https://doi.org/10.1093/rpd/nch572 Published: 2005
Bile acid malabsorption (BAM) is one possible explanation for chronic diarrhea. BAM may be idiopathic, or result from ileal resection inflammation including Crohn's disease, secondary to other conditions, cholecystectomy, peptic ulcer surgery, and pancreatitis. No "gold standard" exists clinical diagnosis of BAM, but response treatment with a bile sequestrant (BAS) often accepted as confirmation. The SeHCAT (tauroselcholic [selenium-75] acid) test uses radiolabeled synthetic provides...
Summary— Dynamic renal scintigraphy is a successful and minimally invasive technique for evaluating function. An extension to the basic involving fast‐frame acquisition modified analysis described which enables ureteric function be examined. Ureteric peristalsis was assessed in 32 patients using this technique. The results from 5 representative studies are detail. Normally functioning ureters exhibit peristaltic contractions at frequency of up 3/min. Hyperperistalsis that exceeds 4...
Although not a cause of progressive renal damage, loin pain and haematuria syndrome is nevertheless associated with significant morbidity. The management often presents formidable problem to urologists, physicians general practitioners. An earlier study noted hold-up urine in the pelvis implicated this pathogenesis pain. In we have failed demonstrate an excess incidence disordered urinary peristalsis syndrome.
The Encyclopaedia of Medical Physics EMITEL was developed under the EU pilot project European Imaging Technology e-Encyclopaedia for Lifelong Learning. This large reference material includes 3400 articles on 2100 pages supported by thousands illustrations. All materials are available free at website, www.emitel2.eu. grouped in seven categories--physics of: X-ray diagnostic radiology, nuclear medicine, radiotherapy, magnetic resonance imaging, ultrasound radiation protection and general...