Marianne Shiew

ORCID: 0000-0003-4774-3576
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Retinal Imaging and Analysis
  • Ophthalmology and Visual Impairment Studies
  • Palliative Care and End-of-Life Issues
  • Cancer Treatment and Pharmacology
  • Retinal and Optic Conditions

Hinchingbrooke Hospital
2019-2022

University of Iowa Hospitals and Clinics
2022

St Thomas' Hospital
2003

East Surrey Hospital
2000

Neovascular age-related macular degeneration (nAMD) is a leading cause of blindness. The first-line therapy anti-vascular endothelial growth factor (anti-VEGF) agents delivered by intravitreal injection. Ionising radiation mitigates key pathogenic processes underlying nAMD, and therefore has therapeutic potential. STAR aimed to assess whether stereotactic radiotherapy (SRT) reduces the number anti-VEGF injections required, without sacrificing visual acuity.

10.1016/s0140-6736(24)00687-1 article EN cc-by The Lancet 2024-06-12

In the UK, macular laser is treatment of choice for people with diabetic oedema central retinal subfield thickness (CST) < 400 μm, as per National Institute Health and Care Excellence guidelines. It remains unclear whether subthreshold micropulse superior should replace standard threshold eligible patients. DIAMONDS a pragmatic, multicentre, allocation-concealed, randomised, equivalence, double-masked clinical trial that aims to determine effectiveness cost-effectiveness compared laser, CST...

10.1186/s13063-019-3199-5 article EN cc-by Trials 2019-02-12

Background The National Institute for Health and Care Excellence recommends macular laser to treat diabetic oedema with a central retinal subfield thickness of &lt; 400 µm on optical coherence tomography. DIAMONDS (DIAbetic Macular Oedema aNd Diode Subthreshold micropulse laser) trial compared standard threshold subthreshold suitable laser. Objectives Determining the clinical effectiveness, safety cost-effectiveness µm. Design A pragmatic, multicentre, allocation-concealed, double-masked,...

10.3310/szki2484 article EN publisher-specific-oa Health Technology Assessment 2022-12-01

The United Kingdom's dead citizens charter was established last year to improve end of life experiences and promote better funeral practices. It identifies 30 areas that need an overhaul, including the availability information for relatives organising a funeral. Institutions such as hospitals, hospices, nursing homes advisers, say National Funerals College, guide rationally through choice directors disposal options. A pilot study is planned. Many general practitioners dream paperless...

10.1136/sbmj.0004130 article EN BMJ 2000-04-01
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