A5090676693- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Vascular Malformations Diagnosis and Treatment
- Ocular Diseases and Behçet’s Syndrome
- Ocular Oncology and Treatments
- Retinopathy of Prematurity Studies
- Angiogenesis and VEGF in Cancer
- Growth Hormone and Insulin-like Growth Factors
- Ophthalmology and Visual Impairment Studies
- Health Systems, Economic Evaluations, Quality of Life
- Neurological Disorders and Treatments
- Meta-analysis and systematic reviews
- Connexins and lens biology
- Pituitary Gland Disorders and Treatments
- Ocular Infections and Treatments
- Ocular and Laser Science Research
- Ocular Surface and Contact Lens
- Advanced Glycation End Products research
- Antiplatelet Therapy and Cardiovascular Diseases
- Child Abuse and Related Trauma
Queen's University Belfast
2015-2025
Belfast Health and Social Care Trust
2017-2023
University of Iowa Hospitals and Clinics
2022
Newcastle University
2022
Hospital Universitario Severo Ochoa
2019
NHS Grampian
2006-2018
Royal Victoria Hospital
2013-2018
University of Ulster
2013-2018
Queen's University
2014
Centre of Experimental Medicine of the Slovak Academy of Sciences
2013-2014
To determine if phenotypic subtypes exist in Stargardt macular dystrophy-fundus flavimaculatus (SMD-FFM).A cross-sectional study of 63 patients with autosomal recessive SMD-FFM was undertaken. The age onset, duration symptoms, visual acuity, and clinical features on fundus examination, color photographs, autofluorescence images were recorded. Electrophysiological tests, including pattern, focal, full-field electroretinogram (ERG), electro-oculogram, color-contrast sensitivity measurement,...
Summary Fundus autofluorescence (AF) imaging by confocal scanning laser ophthalmoscopy has been widely used ophthalmologists in the diagnosis/monitoring of various retinal disorders. It is believed that fundus AF derived from lipofuscin pigment epithelial (RPE) cells; however, direct clinicopathological correlation not possible humans. We examined and microscopy normal C57BL/6 mice different ages. Increasingly strong signals were observed with age neuroretina subretinal/RPE layer...
Purpose.: To determine whether internal limiting membrane (ILM) peeling is effective and cost compared with no in patients idiopathic stage 2 or 3 full-thickness maculay hole (FTMH). Methods.: This was a pragmatic multicenter randomized controlled trial. Eligible participants from nine centers were to ILM (1:1 ratio) addition phacovitrectomy, including detachment removal of the posterior hyaloid gas tamponade. The primary outcome distance visual acuity (VA) at 6 months after surgery....
To describe and classify patterns of abnormal fundus autofluorescence (FAF) in eyes with early nonexudative age-related macular disease (AMD).FAF images were recorded AMD by confocal scanning laser ophthalmoscopy (cSLO) excitation at 488 nm (argon or OPSL laser) emission above 500 521 (barrier filter). A standardized protocol for image acquisition generation mean after automated alignment was applied, routine photographs obtained. FAF classified two independent observers. The kappa statistic...
Purpose.: We characterized subtypes of fundus autofluorescence (AF) and the progression retinal atrophy, correlated these findings with genotype in Stargardt disease. Methods.: Full clinical examination AF imaging was undertaken 68 patients The baseline data were compared to those at follow-up. Patients classified into three subtypes: type 1 had a localized low signal fovea surrounded by homogeneous background, 2 macula heterogeneous background numerous foci abnormal signal, 3 multiple areas...
Purpose.: To investigate the effect(s) of cataract surgery on expression pro-inflammatory genes and proteins in retina using an experimental rodent model. Methods.: An extracapsular lens extraction was performed one eye C57BL/6 mice (n = 24); contralateral unoperated eyes 24) as well from animals 9) served controls. The neurosensory retinal pigment epithelium (RPE)/choroid were collected postoperatively. Expression involved acute inflammatory/injury response, including IL-1β, fibroblast...
The aim of this systematic review is to appraise the evidence for use anti-VEGF drugs and steroids in diabetic macular oedema (DMO) as assessed by change best corrected visual acuity (BCVA), central thickness adverse events
Dalbavancin is a lipoglycopeptide with potent activity against Gram-positive microorganisms, long half-life, favorable safety profile, and high concentration in bone, which makes it an interesting alternative for treatment of osteoarticular infections. We performed multicentric retrospective study all patients infection (septic arthritis, spondylodiscitis, osteomyelitis, or orthopedic implant-related infection) treated at least one dose dalbavancin between 2016 2017 30 institutions Spain.
To evaluate the occurrence of retinal pigment epithelial atrophy in patients with age-related macular degeneration undergoing anti-vascular endothelial growth factor therapy.The study is a retrospective review. Eligible were and choroidal neovascular membranes treated between October 2007 February 2011; they followed for >3 months, fundus photographs fluorescein angiography at baseline autofluorescence near-infrared images follow-up. Demographics, visual acuity, type membranes, number...