A5083139430- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Retinal Imaging and Analysis
- Child Abuse and Related Trauma
- melanin and skin pigmentation
- Photoreceptor and optogenetics research
- Vascular Tumors and Angiosarcomas
- Dermatological and Skeletal Disorders
- Ocular Oncology and Treatments
- Retinopathy of Prematurity Studies
- Ocular Diseases and Behçet’s Syndrome
- Hypertrophic osteoarthropathy and related conditions
- Historical and Scientific Studies
- Connexins and lens biology
- Mitochondrial Function and Pathology
- RNA regulation and disease
- Traumatic Brain Injury and Neurovascular Disturbances
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Traumatic Ocular and Foreign Body Injuries
- Ocular and Laser Science Research
- Neurosurgical Procedures and Complications
Royal Alexandra Hospital
2018-2020
Menoufia University
2008-2020
King Khaled Eye Specialist Hospital
2016-2018
Skåne University Hospital
2017
Lund University
2017
Aberdeen Royal Infirmary
2016
NHS Grampian
2008-2013
University of Aberdeen
2011
To evaluate the occurrence of retinal pigment epithelial atrophy in patients with age-related macular degeneration undergoing anti-vascular endothelial growth factor therapy.The study is a retrospective review. Eligible were and choroidal neovascular membranes treated between October 2007 February 2011; they followed for >3 months, fundus photographs fluorescein angiography at baseline autofluorescence near-infrared images follow-up. Demographics, visual acuity, type membranes, number...
Usher syndrome is the most common cause of deafness associated with visual loss a genetic origin. The purpose this paper to report very severe phenotypic features type 1B in Saudi family affected by positive homozygous splice site mutation MYO7A gene.Affected siblings went through detailed history. Complete ophthalmic examination was done. Imaging colour fundus photography, autofluorescence (AF), and optical coherence tomography (OCT) scans performed. Full field electroretinogram (ffERG)...
The purpose of this study was to evaluate "in vivo" safety trypan blue (TB) in patients undergoing TB-assisted internal limiting membrane or epiretinal peeling.Prospective including 21 (21 eyes) with full-thickness macular hole and/or membrane/epiretinal peeling. Main outcome measures included distance visual acuity, near amplitude P50 and N95 the pattern electroretinogram, fundus autofluorescence; these were assessed preoperatively, at 6 months (n = 21) 12 10) postoperatively.There a...
Purpose: To describe a specific cone–rod dystrophy phenotype in family with the homozygous c.1429G>A; p.Gly477Arg mutation CRB1 . The detailed of subjects this has not been described previously. Methods: Clinical examination included full-field electroretinography and high-resolution widefield retinal imaging uveitis workup. Molecular genetic analysis next-generation sequencing known genes Sanger for segregation analysis. Results: Three affected male siblings (26, 16, 8 years old) were...
To evaluate the outcomes of pneumatic displacement submacular hemorrhage secondary to choroidal neovascular membrane (CNV) (n = 9) and retinal arterial macroaneurysm (RAM) 3). This is a retrospective case series study 12 eyes from patients in Aberdeen Royal Infirmary, Aberdeen, UK. The mean duration visual loss was 10.8 ± 4.11 days. All cases received intravitreal injection expansile gas within 24 h presentation (C3F8 11 SF6 one case) postured face down for five Anterior chamber paracentesis...
Proliferative diabetic retinopathy is a major cause of visual impairment in working-age adults worldwide. Panretinal photocoagulation cornerstone its management; however, it may include range side effects and complications, one these being serous retinal detachment. To the best our knowledge, this first report use intravitreal injection bevacizumab for detachment after panretinal photocoagulation.A 24-year-old Saudi man with poorly controlled type 1 diabetes presented bilateral progressive...
Dear Editor,Alstrom syndrome (ALMS; MIM# 203800) is characterized by early onset cone-rod dystrophy (CRD), sensorineural hearing loss, obesity, cardiomyopathy, pulmonary disease, hepatic r...
Purpose: To report five novel genetic variants in seven unrelated consanguineous families with achromatopsia (ACHM).Methods: Patients were examined multimodal retinal imaging and full-field electroretinography (ffERG). Genetic testing was conducted using next-generation sequencing (NGS).Results: Three homozygous detected CNGA3: a missense c.967G > C (p.Ala323Pro) variant exon 8 (one patient), splice site c.101 + 1G A intron 2 (three patients), c.395 T 4(one patient). Another two found PDE6C:...
To report a severe phenotype of retinitis pigmentosa associated with novel mutations in CNGB1.Six siblings, age range 50-75 years old, were examined using optical coherence tomography and fundus autofluorescene, electroretinogram testing, Goldman visual field genetic testing next generation sequencing.In four affected two compound heterozygous variants CNGB1 detected: exon 26 the missense variant c.2603G > A (p.(Gly868Asp)), 21, in-frame 12-bp duplication c.2093_2104dupGCGACCTCATCT...
Congenital stationary night blindness (CSNB) represents a group of rare, frequently underdiagnosed, genetic disorders that are characterized by non-progressive dim-light visual difficulties (1,2). ...
To report anatomical and visual outcomes of Nd:YAG laser posterior hyaloidotomy (NYPH) in Saudi patients affected by Premacular subhyaloid haemorrhage (PMSHH).8 eyes from 8 (7 males one female) were treated with NYPH when no spontaneous resolution PMSHH was noticed. The cause proliferative diabetic retinopathy (PDR) 3 cases, Central retinal vein occlusion (CRVO) 2 Valsalva pointer injury case. YAG delivered using a Q switched mode mirrors contact lens. One attempt delivery enough 6 cases...
<i>Purpose:</i> To evaluate the tamponade effect on retina of a heavier-than-water silicone oil mixture and to compare it with oil. <i>Methods:</i> Prospective, non-randomised, comparative pilot study. Phakic/pseudophakic patients retinal detachment undergoing vitrectomy Densiron 68 or were recruited. The ‘separation volume’, defined as relative volume space between intraocular agent retina, was estimated using magnetic resonance imaging in both groups compared....
In the medical settings, safety precautions are used to mitigate inadvertent ocular damage due laser beams. High power lasers illegal in many countries; however, they sometimes on social occasions. Use by an untrained member of public can result severe accidental damage. We report a case macular and central visual loss use class IVb 2000 mW 20-year-old male. To our knowledge, this is first injury particular type laser. The history management over 6-month period described. Pubic education...
A 44-year-old Saudi female presented with poor right eye vision for 3 years. Visual acuity (VA) was 20/400 in the and 20/20 left eye. Examination imaging showed all typical features of retinitis pigmentosa associated full thickness macular hole (FTMH) an essentially normal The case underwent pars plana vitrectomy internal limiting membrane peeling gas tamponade that resulted anatomical closure FTMH, but VA remained same.
Background: The purpose of this study is to determine the incidence angioid streak-associated choroidal neovascular membranes (CNV) in UK and provide other epidemiological data, clinical characteristics, therapies used, short-term outcomes following treatment condition. Procedure: This a prospective multicenter cohort study. Patients newly diagnosed streaks-associated CNV were identified prospectively over 14-month period (January 2009-March 2010) by active surveillance through British...
Lois, Noemi MD, PhD; Abdelkader, Ehab PhD, FRCS; McBain, Vikki Anand, Mrinal MS, FRCS(Ed); Scott, Neil W. Siddiqui, M. A. Rehman PhD Author Information