A5040358062- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Carbon and Quantum Dots Applications
- Urinary Bladder and Prostate Research
- Graphene and Nanomaterials Applications
- Thyroid Disorders and Treatments
- Stress Responses and Cortisol
- Pharmacology and Obesity Treatment
- Trace Elements in Health
- Conducting polymers and applications
- Phytase and its Applications
- Systemic Sclerosis and Related Diseases
- Advanced biosensing and bioanalysis techniques
- Nanocluster Synthesis and Applications
- Cardiac Ischemia and Reperfusion
- Muscle metabolism and nutrition
- Endometriosis Research and Treatment
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Pelvic floor disorders treatments
- Luminescence and Fluorescent Materials
- Phytochemical and Pharmacological Studies
- Tissue Engineering and Regenerative Medicine
- Reconstructive Surgery and Microvascular Techniques
- Hypothalamic control of reproductive hormones
- Pregnancy-related medical research
Ankara University
2023-2025
Gazi University
2021-2025
Sağlık Bilimleri Üniversitesi
2020-2021
Gülhane Askerî Tıp Akademisi
2020
Balıkesir University
2017
In this study, the synthesis, characterization, density functional theory calculations (DFT), and effect of polyethylenimine (PEI)-functionalized nitrogen-doped graphene quantum dots (PEI N-GQDs) their palladium metal nanoparticles nanocomposites (PdNPs/PEI on cancer cells were extensively investigated. The focus also includes investigating cytotoxic apoptotic effects ovarian cells, which pose a serious risk to women's health have high death rates from delayed diagnosis, inadequate response...
Abstract Background Androgen deprivation is associated with erectile dysfunction (ED). In different animal models, sulfur dioxide (SO 2 ) donors Na SO 3 and NaHSO reduced oxidative stress, fibrosis, inflammation which contribute to the pathogenesis of androgen deprivation‐induced ED, however effect on ED in castrated rats were not known. Objective To investigate therapeutic donors, /NaHSO , rat model. Materials methods Sprague–Dawley male ( n = 30) divided into four groups; control,...
This study aimed to investigate the role of new adipocytokines (omentin, vaspin, irisin and visfatin) in development endometriosis relationship these with inflammatory marker, C-reactive protein (CRP) levels serum.In this study, (n=16) control groups (n=14) were determined via ultrasound. Serum omentin, vaspin measured by ELISA method. CRP serum gene expression visfatin whole blood samples clinical analyzer real-time polymerase chain reaction, respectively.Serum group significantly higher...
Abstract Objectives Angiogenesis is involved in polycystic ovary syndrome (PCOS) progression. Vascular endothelial growth factor-C (VEGF-C) and its receptors are key angiogenic markers. The main objective of this study was to investigate the serum levels VEGF-C receptors, soluble VEGF receptor 2 (sVEGFR-2) VEGFR-3, patients with PCOS healthy controls determine link between these VEGF-related proteins biochemical hormonal data PCOS. Methods Thirty-six women 30 were included study. measurement...
Background: Erectile Dysfunction (ED) is a common sexual disorder among men aged 20 years and over. It predominantly characterized by alterations in the key physiological pathways regulating erectile function, such as nitric oxide Ras homolog gene family member A (RhoA)/Rho-associated protein kinase (ROCK). Beyond these pathways, multiple molecular signaling networks are involved ED pathogenesis. Objective: This review aims todescribe major signal transduction that impact function contribute...
Colorectal cancer (CRC) remains a crucial health problem due to the toxicity of 5-Fluorouracil (5-FU) as first-line chemotherapy agent for treating CRC. The anticancer effects boron and its compounds have been shown in various cell lines. This study aimed examine cytotoxic apoptotic borax (sodium tetraborate) alone or along with 5-FU on human CRC cells, DLD-1.Cytotoxicity apoptosis were determined by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assay,...
In different animal models, a histone deacetylase (HDAC) inhibitor, sodium butyrate (NaBu) reduced inflammation, oxidative stress and fibrosis which were involved in the pathogenesis of erectile dysfunction (ED), but whether NaBu could improve ED an experimental model benign prostate hyperplasia (BPH) was not known.To investigate preventive effect on partial bladder outlet obstruction (PBOO) rat model.PBOO induced by urethral obstruction. (20 mg/kg/day) administered orally to rats for 6...
Humic substances are commonly found in decaying organic matter including plants, animal residues, sewage and soil. Although fulvic-acid accounts for ∼90% of all its biological significance recognized many years, there is still minimal scientific understanding the claims properties. However, these formulations contain numerous toxic elements that make their use clinically impossible. Recently, has been development a pure form fulvic-acid, carbohydrate derived (CHD-FA) shown to be safe absent...
Abstract Background Sexual dysfunction may indicate severe endocrine diseases. Recent research has suggested a link between hypothyroidism, low testosterone (T) levels, and erectile (ED); however, the exact cause is unknown. Aim We sought to investigate possible beneficial effects of levothyroxine T alone or in combination on ED propylthiouracil (PTU)-induced hypothyroid rats. Methods Adult Wistar rats (n = 35) were divided into 5 groups: control, PTU-induced PTU + levothyroxine, Sustanon (a...
As standard therapy for prostate cancer, radical prostatectomy causes cavernous nerve (CN) injury and increases fibrosis hypoxia-induced penile structural alterations. This study aimed to determine the potential beneficial effects of adipose-derived stem cells (ADSCs) l-arginine alone or in combination on erection a rat model erectile dysfunction caused by bilateral transection (CNT). Male rats (n = 35) were randomized into five groups: Sham-operated; CNT (4-weeks); plus ADSCs (1 × 106...
Objective: Angiogenesis, defined as the formation of new blood vessels from pre-existing ones, plays a vital role in both physiological and pathological conditions. Understanding agents that can influence angiogenesis is crucial managing diseases where dysregulated. This study focuses on sevoflurane, commonly used inhalation anesthetic, whose effects embryonic development are not well understood. Our objective was to assess impact sevoflurane exposure using ex-ovo chick chorioallantoic...
<title>Abstract</title> In this study, we synthesized a new material, Schiff base PEI-CA/N-GQDs, from the reaction of 4-hydroxy-3-methoxy-cinnamaldehyde (CA) with polyethyleneimine-functionalized N-doped graphene quantum dots (PEI N-GQDs). The material was experimentally characterized by FT-IR, UV-Vis, SEM, EDX, AFM, XRD, and TGA, as well theoretically DFT method. addition to their biological activities, cytotoxic, apoptotic cell cycle arresting effects were investigated in human epithelial...