- Catalytic Processes in Materials Science
- Advanced ceramic materials synthesis
- Advanced materials and composites
- ZnO doping and properties
- High Entropy Alloys Studies
- Catalysis and Oxidation Reactions
- Gas Sensing Nanomaterials and Sensors
- Metamaterials and Metasurfaces Applications
- Catalysis and Hydrodesulfurization Studies
- Nonlinear Optical Materials Studies
- Polyoxometalates: Synthesis and Applications
- Ferroelectric and Piezoelectric Materials
- Inflammatory Bowel Disease
- Mesoporous Materials and Catalysis
- Neuroscience and Neuropharmacology Research
- Advanced Antenna and Metasurface Technologies
- Microscopic Colitis
- Nonlinear Optical Materials Research
- Electromagnetic wave absorption materials
- Heme Oxygenase-1 and Carbon Monoxide
- Geochemistry and Elemental Analysis
- Eosinophilic Esophagitis
- Semiconductor Quantum Structures and Devices
- High-Temperature Coating Behaviors
- Neurological Disease Mechanisms and Treatments
Chongqing Medical University
2008-2025
Eli Lilly (United States)
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2008-2025
Chinese Academy of Fishery Sciences
2024
Shijiazhuang Tiedao University
2015-2024
Shanghai Sixth People's Hospital
2009-2024
Shanghai Jiao Tong University
2001-2023
Shantou University
2020-2022
Shantou University Medical College
2020-2022
Wuhan Business University
2012-2022
Abstract Background Mirikizumab, an anti-IL-23p19 antibody, demonstrated robust efficacy in improving clinical and endoscopic endpoints with acceptable safety profile1. We explored the trajectory of response to treatment patients moderate-to-severely active Crohn’s disease (CD), treated mirikizumab based on biofailed status at study baseline. Methods Biofailed was defined as intolerance, inadequate response, or loss approved biologic therapy for CD (BF, N=275) Not (NBF, N=297) described...
Abstract Background Mirikizumab (miri), an anti-IL-23p19 antibody, has shown efficacy in treatment of patients with moderately to severely active Crohn’s disease (CD) a Phase 3 study VIVID-1 (NCT03926130). We evaluated the associations inflammatory biomarkers, fecal calprotectin (FC) and C-reactive protein (CRP), clinical, endoscopic, histologic improvement randomised miri. Methods achieved primary key secondary endpoints published previously1. The mean change from baseline FC CRP was...
Abstract Background Mirikizumab (Miri), an interleukin-23p19 inhibitor, has shown strong efficacy and was well-tolerated in patients with moderately-to-severely active Crohn’s disease (CD) the Phase 3 study VIVID-1 (NCT03926130) (1). We report one-year safety of Miri treated ustekinumab (Ust) who enrolled open label extension VIVID-2 (NCT04232553). Methods Patients completed VIVID-1, on Ust 6mg/kg intravenous (IV) at week (W) 0, then 90mg subcutaneous (SC) every 8 weeks, received Miri. Dose...
Abstract Background Histologic inflammation persists in up to 1/4 of patients with Crohn’s disease (CD) despite endoscopic mucosal healing. and combined endoscopic-histologic endpoints are evolving measures treatment efficacy CD; however, the impact histologic healing on long-term outcomes progression is unknown. Week (W) 52 data comparing mirikizumab (Miri) vs placebo (PBO) randomized, double-blind, placebo- active-controlled, treat-through Phase 3 VIVID-1 trial moderately-to-severely...
Acute intermittent porphyria (AIP) is an inherited metabolic disorder that can affect the central, peripheral, and autonomic nervous systems. Therefore, its clinical presentation diverse may include abdominal pain, as well neurological psychiatric symptoms. Abdominal though a common initial symptom, often overlooked or misdiagnosed due to lack of specificity. But early diagnosis treatment are crucial, untreated symptoms progressively worsen. This report describes 26-year-old male who was...
Low-leaded perovskite solar cells are operated using inorganic active metal substitution of lesser organometal halide perovskite.
In this paper, cerium was incorporated into polyhydroxyltriacetictin (PHTES) using the sol-gel method combined with electrospinning technology to prepare a series of composite oxide fiber catalysts SnxCe1−xO2 in different proportions. The structures and soot catalytic activities fibers were studied under loose contact conditions. When Ce entered crystal lattice SnO2, structural symmetry SnO2 destroyed, which inhibited crystallization grain growth fiber, larger specific surface area obtained....
We report the far-infrared (FIR) reflection measurements of Pb1-xSrxSe thin films with different Sr concentrations grown by molecular beam epitaxy on BaF2 substrates. composition and lattice parameter have been assessed x-ray diffraction. By fitting FIR spectra comparison results binary PbSe SrSe films, both PbSe-like SrSe-like optical phonon bands in ternary PbSrSe identified. Also, carrier concentration mobility extracted from theoretical calculation spectra, are found to be agreement...
Titanium diboride (TiB<sub>2</sub>) materials have garnered significant attention due to their remarkable comprehensive properties. They offer potential applications in high-temperature structural materials, cutting tools, armor, electrodes for metal smelting, and wear-resistant parts. However, the low self-diffusion coefficient, TiB<sub>2</sub> exhibits poor sinterability, excessive grain growth at elevated temperatures, inadequate oxidation resistance, limiting its...
Key properties of PbSrSe thin films grown by molecular beam epitaxy have been studied for mid-infrared optoelectronic device applications. Detailed knowledge the material parameters design is required. The considered are: temperature-dependent band gaps, composition (or gap)-dependent effective masses, and energy-dependent refractive indices. study has carried out a combination photoluminescence absorption measurements with theoretical models on Sr compositions as high 0.276. derived...
Abstract Single crystal growth of the organic nonlinear optical crystal, L‐arginine trifluoroacetate (L‐Arg·CF 3 COOH, abbreviated as LATF) is reported. Low temperature solution method employed for bulk single crystals. The cell parameters are verified by diffraction. Fourier transform infrared (FT‐IR) and Raman analysis used to confirm presence various functional groups in grown crystal. thermal properties crystals studied thermogravimetric differential scanning calorinetry (TGA/DSC)....
The third-order nonlinear optical properties of two dmit organometallic complexes, [(CH3)4N] [Au(C3S5)2] (MeAu) and [(CH3)4N][Ni(C3S5)2] (Me Ni) in acetone solutions, were characterized us- ing a short pulse Z-scan technique at 1064 nm wavelength. Self-defocusing effects found both samples stronger saturable absorp-tion was observed MeNi solution comparing with that MeAu. origins analyzed for the differences between results. Two figures merit W T also calculated to evalu-ate suitability...