A5101702900- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Neonatal Health and Biochemistry
- Immunodeficiency and Autoimmune Disorders
- Congenital Anomalies and Fetal Surgery
- Nonmelanoma Skin Cancer Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Neonatal and Maternal Infections
- Cell Adhesion Molecules Research
- Autoimmune and Inflammatory Disorders
- Infant Nutrition and Health
- Child Nutrition and Water Access
- Respiratory Support and Mechanisms
- Renal and Vascular Pathologies
- Pediatric Urology and Nephrology Studies
- Infant Development and Preterm Care
- Vascular Malformations Diagnosis and Treatment
- Skin Protection and Aging
- Hearing Loss and Rehabilitation
- Diabetic Foot Ulcer Assessment and Management
- Cerebrospinal fluid and hydrocephalus
- Neuroscience of respiration and sleep
- Hearing, Cochlea, Tinnitus, Genetics
- Trace Elements in Health
Chang Gung University
2010-2021
Chang Gung Memorial Hospital
2003-2021
Chang Gung Children's Hospital
2014-2021
University of Southern California
2014-2016
Children's Hospital of Los Angeles
2014-2016
LAC+USC Medical Center
2016
Memorial Hospital of South Bend
2003
Abstract Development of the mammalian lung is predicated on cross-communications between two highly interactive tissues, endodermally derived epithelium and mesodermally pulmonary mesenchyme. While much attention has been paid for epithelium, mesenchyme, partly due to lack specific tractable markers remains under-investigated. The mesenchyme from lateral plate mesoderm principal recipient Hedgehog (Hh) signaling, a morphogenetic network that regulates multiple aspects embryonic development....
ABSTRACT Postnatal alveolar formation is the most important and least understood phase of lung development. Alveolar pathologies are prominent in neonatal adult diseases. The mechanisms alveologenesis remain largely unknown. We inactivated Pdgfra postnatally secondary crest myofibroblasts (SCMF), a subpopulation mesenchymal cells. Lack arrested akin to bronchopulmonary dysplasia (BPD), chronic disease. transcriptome mutant SCMF revealed 1808 altered genes encoding transcription factors,...
"Late preterm" defines infants born at 34(0/7) through 36(6/7) weeks' gestation, which comprise a majority of preterm births. These were treated clinically as "near-term" in the past, but recent studies have implied increased morbidities that differentiate late and term infants. The purpose this study was to examine prevalence clinical complications could be associated with birth, compared term.This retrospective cohort reviewed medical center Northern Taiwan during 2-year period between...
Although significant advances have been made in perinatal care, retinopathy of prematurity (ROP) remains a serious complication prematurely born individuals. There limited studies on ROP Taiwan, and most those existing reports are outdated.This retrospective study included 252 very-low-birth-weight (VLBW) infants admitted to the neonatal intensive care unit Chang Gung Children's Hospital over 2-year period between July 2005 June 2007. All were examined for according guidelines published by...
We describe a new method for treating livedoid vasculopathy. The typical presentation of vasculopathy includes chronic, recurrent painful ulcers, satellite scar‐like atrophy and telangiectasia involving the lower extremities. Histologically, these lesions show areas ulceration dermal vessel occlusion without frank inflammatory cell infiltration. There is currently no satisfactory therapy available this disease. Hyperbaric oxygen (HBO) has recently established itself as one most effective...
BackgroundGroup B streptococcus (GBS) infections can be life-threatening in newborns. This study aimed to analyze GBS carriage status and genotypic diversity healthy neonates after implementation of intrapartum antibiotic prophylaxis (IAP) Taiwan.MethodsNewborns carrying were identified from a screen 500 newborns followed up until their cultures turned negative. Their mothers' screening data reviewed. Molecular methods, including capsular serotyping, multilocus sequence typing pulsed-field...
There is a lack of evidence to guide step-wise weaning positive pressure respiratory support for premature infants. This study sought compare the efficacy three protocols we designed facilitate very low birth weight (VLBW, less than 1500 g) preterm infants from nasal continuous airway (NCPAP) support. was prospective, randomized, controlled trial VLBW who received ventilatory in our neonatal intensive care unit (NICU) April 2008 through March 2009. When these were weaned CPAP as their last...
Trace elements are vital components for healthy growth, development, and physical activity. The aim of this study was to investigate the relationship between trace element (iron, zinc, copper) deficiencies picky eating behavior, development level, activity level. This cross-sectional involved 203 children aged 4–7 years; level were assessed through questionnaires. Zinc deficiency has highest prevalence (37.4%); 67.5% as eaters. Children with behaviors, poor or have significantly lower zinc...
<i>Background:</i> Wiskott-Aldrich syndrome (WAS) is an X-linked immunodeficiency, characterized by microthrombocytopenia, eczema and recurrent infections. More than 441 patient mutations have been described all over the world, mainly based on Caucasian Japanese people. There few reported cases involving Chinese WAS patients. <i>Objective:</i> We investigated patients in Taiwan since 1980. <i>Methods:</i> All met diagnosis criteria. Clinical...
Neonatal renal vein thrombosis is the most common vascular condition in newborn kidney, which could lead to serious complication infants undergoing intensive care. In this study, we report case of a preterm infant with left and inferior vena cava thrombosis, presented gross hematuria, thrombocytopenia, transient hypertension, adrenal hemorrhage. Supportive care was offered instead heparin therapy or thrombolytic agents. conclusion, our teaches that, despite lack clinically obvious shock...
<h3>Background</h3> Concurrent use of methotrexate (MTX) and trimethoprim-sulfamethoxazole (TMP-SMX) has been linked to the development cytopenia as a result reduced renal clearance MTX. However, risk adverse outcomes not estimated in population setting. <h3>Objectives</h3> This study aimed examine for emergency department visits or hospitalisation after concurrent MEX TMP-SMX patients with rheumatoid arthritis (RA) Taiwan using National Health Insurance (NHI) data. <h3>Methods</h3> was...