Neonatal sepsis (NS) continues to be the one of major problems in neonatal practice. This is due variability clinical manifestations and, part, lack available diagnostic markers that are significantly associated with mortality as a result sepsis. The purpose - study role paraclinical myocardial dysfunction neonates Materials and methods. To achieve this goal, 87 newborns (the main group) generalized infectious-inflammatory process were under our observation. control group included 30...

Infantile haemangiomas are the most common benign vascular tumours of childhood.Multifocal infantile haemangiomatosis with visceral involvement newborn is a rareand potentially fatal entity in infants, present at birth or arising during first week life.The article presents clinical- paraclinical features course multifocal infantilehaemangiomatosis neonatal period.The presented clinical case demonstrates that timely appointment non-selectiveβ-blockers (propranolol) main element treatment and...

Background. Leucinosis ("maple syrup urine disease ") is a hereditary with an autosomal recessive type of inheritance, the basis which violation metabolism organic amino acids. The characterized by development life-threatening condition, accompanied developmental delay, suppression neuro-reflex excitability, specific smell (the "maple syrup"), ketoacidosis, hypoglycemia. There are five clinical phenotypes leucinosis: classic, intermediate, intermittent, E3-deficient, and thiamine-sensitive....

Neonatal sepsis remains the main cause of morbidity and mortality in neonatal intensive care units. In particular, share structure respiratory failure reaches 35.3%. At same time, search for sensitive indicators critical course acute distress syndrome against background septic process relevant. Objective. To study peculiarities dynamics treatment premature babies with sepsis, depending on gestational age. Material methods. achieve this goal, conditions Intensive Care Unit Regional Municipal...

Neonatal diabetes mellitus (NDM) is a rare genetic disorder affecting 1 in 90,000 to 160,000 live births. NDM defined by the presence of severe hyperglycemia associated with insufficient or absent circulating insulin, which occurs mainly before age 6 months and rarely between ages year. Based on duration insulin depen­dence, two main types disease have been described: transient neonatal diabetes, accounts for 50—60 % cases usually resolves 18 age, permanent less common definition does not go...

Introduction: Nowadays, the issues of early diagnostics cardiovascular disorders in neonates with sepsis use up-to-date methods examination that can be applied as screening aim to verify possible development dysfunction remain urgent. To study certain clinical-instrumental parameters and biochemical markers depending on gestational age improve prognosis neonatal (NS). Materials Methods: realize objective, 57 were under our observation verified diagnosis “NS.” I Group (23 patients – 40.3%)...

Актуальність. Інгаляційні глюкокортикостероїди (іГКС) відіграють зараз провідну роль у лікуванні бронхіальної астми (БА) на етапі як досягнення, так і підтримки повного контролю за клінічними симптомами захворювання. Відомо, що застосування іГКС високих дозах може супроводжуватися системними побічними ефектами, найбільш тривожним із них є пригнічення функціональної активності гіпоталамо-гіпофізарно-надниркової системи. Проте особливості перебігу захворювання та зміни кортизол-продукуючої...

The problem of perinatal morbidity and mortality remains one the main medical problems today in all countries world. prevalence pathology is constantly increasing. damage to nervous system about 50% structure childhood disability with 70-80% cases lesions. We present our own observations child central undefined etiology.

Objective. To evaluate the effectiveness of inhaled glucocorticosteroids in children with atopic and non-atopic asthma phenotypes depending on acetylation status.Material methods. A complex clinico-immunological examination involved 119 bronchial asthma. The genetic marker, namely type acetylation, has been identified by method V. M. Prebsting — I. Gavrilova modification Timofeeva. They were divided into four clinical groups: group I 36 (ABA) slow (patients’ average age 13,4±0,6 years,...

Objective. To study the clinical-anamnestic features of bronchial asthma course in schoolchildren who were born with low birth weight (LBW).Material and methods. achieve goal research a cohort school-age children (61 patients) persistent (BA) receiving in-patient treatment at Regional Children's Clinical Hospital Chernivtsi was formed by simple random sample. Depending on patients' body two groups clinical observation formed. The first (I) group included 35 (≤ 2500 g), second (II) control...

Nowadays childhood hematology-oncology diseases are an actual problem of health care. According to the WHO classification, transient abnormal myelopoiesis (TAM) belongs group clonal myeloproliferative diseases. This rare disorder can be observed in almost 5-10 % newborns with syndrome chromosomal instability, including Down syndrome.A significant role development TAM has been given intrauterine appearance somatic mutation X-linked gene GATA1 that encodes a transcription factor which is...

Congenital adrenal cortex hyperplasia combines a group of monogenic diseases with an autosomal recessive fashion based on defects in enzymes or transport proteins involved steroidogenesis. This disease proceeds under variety clinical masks, which leads to the development severe exsicosis electrolyte disorders and without replacement therapy can result mortality. It requires doctors be cautious adequately skilled assisting newborns. The article presents paraclinical features course...

Мета – проаналізувати клінічний випадок внутрішньоутробного мікст-інфікування у новонародженої дитини.
 В останні роки відзначається зростання частоти та поширеності внутрішньоутробних інфекцій, які є провідними структурі захворюваності смертності немовлят. Серед них провідну роль посідає родина герпесвірусів, до яких належить й цитомегаловірус (ЦМВ). Здатність вірусу спричиняти тяжке ураження плода можливе будь-якому триместрі вагітності, особливо випадках первинного зараження під час...

Введение. Сердечно-сосудистые нарушения в неонатальном периоде представляют собой совокупность нарушений, возникающих у новорожденных со стороны сердечно-сосудистой системы ответ на сопутствующую патологию или другие патологические состояния. Цель. Определить диагностическую ценность биомаркеров поражения с инфекционной и неинфекционной патологией. Материалы методы. Обследовано 52 новорожденных. Сформированы две клинические группы наблюдения: I группа (48,1) включала верифицированным...

Neonatal sepsis (NS) is the leading cause of morbidity and mortality in intensive care units. The issue early diagnosis a purulent-septic process newborns using modern research methods that can be used as screening for verifying remains relevant. Objective. To conduct comparative analysis clinical laboratory features course late neonatal to optimize infectious-inflammatory at stage obstetric institutions. Material methods. achieve this goal, retrospectively 26 medical records institutions...

The formation of myocardial dysfunction in neonatal sepsis remains a topical issue current practice. Myocardial with is found to promote double increase loss rate, and maintenance an adequate cardiac output very important predictor for survival patients sepsis. Purpose - study clinico-paraclinical markers case alternative term debut timely verification rational correction cardiovascular disorders. Materials methods. Considering various terms manifestation its early late variants, comparative...

The issues of early diagnostics cardiovascular disorders in neonates with sepsis using up-to-date methods examination are relevant today and will remain so the future. They can be used as screening purpose to verify possible development dysfunction. Aim study: study aimed investigate peculiarities changes system physiological electrical heart activity signs generalised infectious-inflammatory process, assess diagnostic use electrocardiography newborns neonatal sepsis. Materials methods: To...

A lot of data concerning the epidemiological features pathogen, clinical andparaclinical characteristics disease, principles diagnosis and approaches tothe treatment have been published in scientific literature during year pandemiacaused by SARS-CoV-2. But still there are many unresolved issues regarding theepidemiological this coronavirus infection newborns.Purpose – to conduct observational study peculiarities SARS-CoV-2 coronavirusinfection newborns treated 2020 on basis RCNE "Chernivtsi...

The problem of neonatal sepsis continues to be one the leading places in practice. issues early diagnostics cardiovascular disorders neonates with by means up-to-date methods examination remain relevant. They can used as screening purpose verify possible development dysfunction. Purpose — study meaning certain clinical and paraclinical markers myocardial dysfunction sepsis. Materials methods. In order realize objective we have observed 69 signs generalized infectious-inflammatory process....

neonatal sepsis remains one of the leading causes morbidity and mortality in age. The involvement myocardium insufficiently studied, particular neonatology, where issues myocardial dysfunction generalized infection seem even more controversial, especially at different gestational terms. Objective. To study specific clinical anamnestic echocardiographic parameters infants depending on age for optimization prognosis sepsis. Material research methods. achieve this goal, we observed 57 newborns...

Congenital nephrotic syndrome (CNS) is an inherited disease that caused by gene mutations and autosomal-recessive mechanism. In most cases, it associated with genetically mediated defects in the components of glomerular filtration barrier, especially nephrine podocytes, a typical histological picture diffuse mesenteric sclerosis or focal-segmental glomerulosclerosis. According to genetic research, primary CNS one five genes (NPHS1, NPHS2, WT1, LAMB2, PLCE1) chromosomal abnormalities....

neonatal sepsis remains one of the leading causes morbidity and mortality in age. Theinvolvement myocardium insufficiently studied, particular neonatology, where issues ofmyocardial dysfunction generalized infection seem even more controversial, especially sepsisat different gestational terms. Objective. To study specific clinical anamnestic echocardiographic parametersin infants depending on age for optimization prognosis sepsis. Material researchmethods. achieve this goal, we observed 57...