D. N. Kazakov

ORCID: 0000-0003-0263-6670
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About
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Research Areas
  • Long-Term Effects of COVID-19
  • Intensive Care Unit Cognitive Disorders
  • Acute Ischemic Stroke Management
  • Respiratory Support and Mechanisms
  • Stroke Rehabilitation and Recovery
  • Blood Pressure and Hypertension Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Neurological Disease Mechanisms and Treatments
  • Neurological Disorders and Treatments
  • COVID-19 Clinical Research Studies

Moscow Clinical Scientific Center
2025

City Clinical Hospital
2021

Thrombolytic therapy (TLT) of ischemic stroke (IS) with alteplase within the first 4.5 hours from onset symptoms is most effective and proven method treatment. Objective: to evaluate safety efficacy TLT Revelisa (alteplase) in IS real-world clinical practice. Material methods. The results were analyzed 1181 patients IS: 616 (52.2%) women 565 (47.8%) men (mean age 68.28±12.56 years), which 140 (11.9%) staged reperfusion. mean time disease was 2.58±0.83 hours. Heidelberg classification used...

10.14412/2074-2711-2025-1-57-66 article EN cc-by Neurology neuropsychiatry Psychosomatics 2025-02-17

Introduction. During the SARS-CoV-2 pandemic, worldwide healthcare system faced a new, insufficiently investigated, fast-spreading disease with multisystem failure and relatively high amount of severe diseased. Existing evidence base needs to be frequently revisited after data accumulation analysis. Experience dedicated COVID-19 centers should summarized implicated in clinical practice according evidence-based principles, extensive trial initiation. Objectives. To investigate baseline...

10.21320/1818-474x-2021-3-47-60 article EN cc-by-nc-sa Annals of critical care 2021-10-26

Objective: to study the use of RRT methods and their influence on results treatment patients with severe COVID-19. Subjects methods. We retrospectively analyzed data 283 COVID-19 in intensive care units Moscow City Hospital no. 40 2020 who had received as one Results. Frequency ICU for made 5.7% (504 out 8.711 treated RRT). In 86% cases, was performed renal indications. At time initiation RRT, studied groups did not differ according SOFA score. The frequency using dialysis high low cut-off...

10.21292/2078-5658-2021-18-2-23-30 article EN cc-by Messenger of Anesthesiology and Resuscitation 2021-05-03

Given the current high incidence of cerebral circulatory disorders and challenging treatment such patients, developing therapies medications for these conditions is urgent. The proportion patients undergoing various reperfusion techniques increasing, so medical community's need novel agents with efficacy low complication rate.

10.26442/20751753.2022.11.202025 article EN cc-by Consilium Medicum 2023-01-05
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