After heart transplantation, respiration-synchronous fluctuations (0.18 to 0.35 Hz, high frequency [HF]) in RR interval may result from atrial stretch caused by changes venous return, but slower (0.03 0.15 low [LF]) not due respiration suggest reinnervation. In normal subjects, sinusoidal neck suction selectively stimulates carotid baroreceptors and causes reflex oscillations of interval.To evaluate the presence reinnervation, we measured power RR-LF RR-HF 26 transplant recipients 16 control...

Objectives: To investigate the occurrence of enhanced low-density lipoprotein (LDL) oxidation as an additional factor promoting atherosclerosis progression in hypertensive patients. Design: The plasma LDL was investigated a group untreated patients with mild-to-moderate essential hypertension without clinically evident target organ damage and control subjects. Methods: evaluated both susceptibility to vitro presence anti-oxidized antibodies (as index for vivo). Results: from subjects...

We have previously reported that low-density lipoproteins (LDL) isolated from patients with essential hypertension are more susceptible to in vitro oxidation than normotensive control subjects. In the present study we investigated occurrence of vivo LDL hypertensive patients.The presence antioxidatively modified autoantibodies was taken as a suitable index because, after oxidative modifications, express antigenic epitopes elicit an immune response. The antibody titres were measured plasma...

Summary: Low density lipoprotein (LDL) oxidation plays a crucial role in the development and progression of atherosclerosis is enhanced patients with essential hypertension. This finding has stimulated search for antihypertensive drugs high intrinsic antioxidant properties. We investigated effects carvedilol, new vasodilating β-adrenoceptor blocking agent group mild to moderate hypertension after 4-month treatment. Carvedilol administration markedly increased resistance LDL isolated from...

La calidad en la innovación dentro del sector de construcción debe ser rápidamente adaptada para cumplir con los inmediatos desafíos relacionados mejora las edificaciones actuales. NEST es una plataforma investigación y transferencia tecnológica flexible abierta a universidades e industrias donde nuevas soluciones pueden implementadas validadas un entorno real. consiste estructura fija serie módulos individuales que son utilizados como oficinas o apartamentos poder vivir trabajar. Además,...

1. Although the high-frequency fluctuations in R—R interval (respiratory sinus arrhythmia) observed heart transplant recipients are not a reliable marker of reinnervation because previously shown direct mechanical effect breathing, presence non-respiration-related low-frequency oscillation reflects rhythms generated outside heart, and thus could be neurally mediated. 2. To evaluate reinnervation, spontaneous variability was investigated, supine after passive tilting, 23 (age 43 years, range...

To investigate the correlation between ultrasonographically evaluated intima-media thickness (IMT) of common carotid artery (CCA) and cardiovascular risk factors for subjects with newly detected, uncomplicated untreated primary hypertension.The study population consisted 200 (123 men 77 women, aged 46+/-7.5 years). Blood pressure was measured in clinical setting by 24 h noninvasive ambulatory monitoring. Fasting levels blood glucose, plasma lipids lipoproteins, fibrinogen plasminogen...

The medium‐term (16 weeks) effects of the combination captopril and hydrochlorothiazide (HCTZ) on some metabolic indexes, particularly plasma lipoproteins, were evaluated in 20 mild to moderate hypertensive outpatients. After a 4‐week wash‐out period, subjects given one tablet new commercially available fixed once/daily (i.e., 50 mg + HCTZ 25 mg). dose could be titrated maximum twice daily according individual blood pressure responses. Both systolic diastolic significantly decreased at week...

Cardiomyopathies represent a heterogeneous group of diseases, with significant mortality, which often lead to progressive heart failure. may be primary (hypertrophic cardiomyopathy or infiltrative cardiomyopathies) secondary (for example: hypertension athletic syndrome). The athlete’s is condition in systematic training person determines physiological adaptation heart, generally represented by benign increase cardiac mass specific alteration morphology. There are two types exercise:...

Nel nostro studio abbiamo confrontato, in soggetti ipertesi di prima diagnosi, il diverso impatto, nei due sessi, della presenza Sindrome Metabolica (SM) sulle alterazioni ecocardiografiche del ventricolo sinistro (VS) come espressione danno d’organo subclinico. In 354 diagnosi (108 sesso femminile e 246 maschile), mai trattati, riscontrato uguale prevalenza SM tra i ma diversa dei singoli fattori: glicemia trigliceridi sono piu frequentemente elevati negli uomini, mentre la circonferenza...

Nell’ambito di una popolazione soggetti ipertesi prima diagnosi, senza comorbidita, danni d’organo clinicamente manifesti, mai trattati in precedenza, abbiamo valutato le differenze fra i sesso femminile e quelli maschile per quanto riguarda il livello rischio cardiovascolare globale la presenza sindrome metabolica (SM) definita secondo criteri ATP III, allo scopo evidenziare quali sono principali parametri che distinguono due sessi. I 523 soggetti, 165 358 maschile, stati sottoposti a:...

Very high serum levels of GGT represented a proved index alcohol hepatotoxicity and hepatosteatosis. However still in normal range was found as an independent marker metabolic syndrome important predictor cardiovascular disease. In our study enrolled 339 subject, 94 female 245 male, affected by hypertension never treated, without diabetes or cardiovasculare desease. We evaluated anthropometric parameters, ECG, venous sample, cardiac ultrasound, EBPM each we had also calculated the Framingham...

Un legame fra iperuricemia e disordini cardiovascolari stato ipotizzato da decenni. Non mai chiarito comunque se l’acido urico (AU) rappresenti solo un marcatore di rischio o sia vero fattore rischio. Questo studio si proposto verificare, in soggetti ipertesi prima diagnosi, l’esistenza una correlazione tra uricemia parametri classici cardiovascolare (RCV) nonche presenza danno d’organo subclinico, cardiaco che renale. Sono stati arruolati 534 (166 donne 368 uomini, eta media 47 anni)...

Hypertensive heart disease and cardiac amyloidosis are similar for the increasing of left ventricular mass (LVM) but differ from electrocardiographic aspects. Although in it was observed an increased wall thick-ness, ECG doesn’t show any hypertrophy (LVH) signs, particular high QRS voltages. Low spread voltages often detected, especially inferior leads due to composition electrically inert mate-rial amyloid fibrils. In patients with hypertension, although rarely, reversion normal values...

Las Scrophulariaceae en el Uruguay están representadas por 22 géneros y 44 especies. 11 32 especies indígenas; 8 12 adventicias. Se citan primera vez para país: los Melasma Digitalis; las especies: Scoparia ericacea, rhinanthoides, Micranthemum tweediei, Stemodia stricta, Mecardonia tenella v. microphylla, Digitalis purpurea.