A5065121190- Hearing, Cochlea, Tinnitus, Genetics
- Hearing Loss and Rehabilitation
- Noise Effects and Management
- Vestibular and auditory disorders
- Ear Surgery and Otitis Media
- Urological Disorders and Treatments
- Neuroscience of respiration and sleep
- Urinary Tract Infections Management
- Urinary Bladder and Prostate Research
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Fatty Acid Research and Health
- Clinical practice guidelines implementation
- Advanced Statistical Methods and Models
- Smoking Behavior and Cessation
- Kidney Stones and Urolithiasis Treatments
- Nutritional Studies and Diet
- Advanced Statistical Process Monitoring
- Cerebral Venous Sinus Thrombosis
- Reliability and Agreement in Measurement
- Acne and Rosacea Treatments and Effects
- Human Health and Disease
- Meta-analysis and systematic reviews
- Music and Audio Processing
- Advanced Glycation End Products research
Brigham and Women's Hospital
2015-2024
Harvard University
2010-2024
Harvard University Press
2023
Health Affairs
2018
Vanderbilt University
2016
National Institutes of Health
1999
<h3>Context</h3>Hearing loss is common and, in young persons, can compromise social development, communication skills, and educational achievement.<h3>Objective</h3>To examine the current prevalence of hearing US adolescents determine whether it has changed over time.<h3>Design</h3>Cross-sectional analyses representative demographic audiometric data from 1988 through 1994 2005 2006 time periods.<h3>Setting</h3>The Third National Health Nutrition Examination Survey (NHANES III), 1988-1994,...
Interstitial cystitis is a chronic and debilitating syndrome but surprisingly little known about its epidemiology. This study was designed to estimate the prevalence of interstitial among women in United States.Female participants Nurses' Health Study (NHS) I II (184,583) were asked by mailed questionnaires whether they had ever been diagnosed with cystitis. We requested reviewed medical records self-reporting The accuracy self-reports evaluated using standardized criteria.Among 93,428 who...
Abstract Objectives/Hypothesis: Hearing loss is the most common sensory disorder in United States, affecting more than 36 million people. Cardiovascular risk factors have been associated with of hearing cross‐sectional studies, but prospective data are currently lacking. Study Design: Prospective cohort study. Methods: We prospectively evaluated association between diagnosis hypertension, diabetes mellitus, hypercholesterolemia, smoking, or body mass index (BMI) and incident loss....
Abstract Introduction We examined the relation between self‐reported hearing loss, aid use, and risk of subjective cognitive function (SCF) decline. Methods conducted an 8‐year (2008–2016) longitudinal study 10,107 men aged ≥62 years who reported their status in 2006 had no concerns 2008. Change SCF scores was assessed by a 6‐item questionnaire, decline defined as new report at least one concern during follow‐up. Results Hearing loss associated with higher Compared multivariable‐adjusted...
Abstract Hearing difficulty (HD) is a major health burden in older adults. While ageing-related changes the peripheral auditory system play an important role, genetic variation associated with brain structure and function could also be involved HD predisposition. We analysed large-scale genome-wide association study (GWAS; ntotal = 501 825, 56% females) GWAS data related to 3935 imaging-derived phenotypes (IDPs) assessed up 33 224 individuals (52% using multiple MRI modalities. To...
Use of analgesics is common and associated with increased risk hearing loss in men; however, the relation has not been examined prospectively women. The authors between frequency aspirin, ibuprofen, acetaminophen use among 62,261 women aged 31–48 years at baseline (1995) Nurses' Health Study II. outcome was self-reported (n = 10,012), follow-up period 1995–2009. Cox proportional hazards regression used to adjust for potential confounders. During 764,247 person-years follow-up, ibuprofen were...
Hearing loss is the most common sensory disorder in United States, afflicting more than 36 million people. Higher intakes of vitamins C, E, beta carotene, B12, and folate have been proposed to reduce risk hearing loss.We prospectively evaluated association between intake from foods supplements folate, incidence loss.Health Professionals Follow-up Study.A total 26,273 men aged 40 74 years at baseline 1986. Participants completed questionnaires about lifestyle medical history every two diet...
Menopause may be a risk factor for hearing loss, and postmenopausal hormone therapy (HT) has been proposed to slow decline; however, there are no large prospective studies. We prospectively examined the independent relations between menopause HT of self-reported loss.Prospective cohort study among 80,972 women in Nurses' Health Study II, baseline age 27 44 years, followed from 1991 2013. Baseline updated information was obtained detailed validated biennial questionnaires. Cox...
We investigated the relation between self-reported hearing loss and risk of subjective cognitive function (SCF) decline among women.We conducted a longitudinal study 20,193 women in Nurses' Health Study aged ≥66 years who reported their status had no concerns 2012. SCF scores were assessed by 7-item questionnaire 2012 2014. was defined as new report at least one concern during follow-up.Self-reported associated with higher decline. Compared loss, multivariable-adjusted odds ratios (95%...
Background We investigated the longitudinal association of herpes zoster (HZ), commonly known as "shingles," and long-term risk stroke or coronary heart disease (CHD) among participants in 3 large US cohorts, NHS (Nurses' Health Study), II Study II), HPFS (Health Professionals Follow-Up Study). Methods Results Participants were 79 658 women (2000-2016), 93 932 (2001-2017), 31 440 men (2004-2016), without prior CHD. Information on HZ, stroke, CHD was collected biennial questionnaires...
We conducted a prospective study of dietary patterns and longitudinal change in audiometric hearing thresholds among 3,135 women (mean age = 59 years) the Nurses' Health Study II (2012-2018). Diet adherence scores for Dietary Approaches to Stop Hypertension (DASH) Alternate Mediterranean (AMED) diets Healthy Eating Index 2010 (AHEI-2010) were calculated using validated food-frequency questionnaires. Baseline 3-year follow-up sensitivities assessed by pure-tone audiometry at 19 US sites. used...
Hearing problems (HP) in adults are common and associated with several comorbid conditions. Its prevalence increases age, reflecting the cumulative effect of environmental factors genetic predisposition. Although risk loci have been already identified, HP biology epidemiology still insufficiently investigated by large-scale studies.
Hearing loss is a common and disabling sensory disorder, yet prospective data on potentially modifiable risk factors are limited. Previous studies suggest that alcohol consumption may influence the development of hearing loss, results have been inconsistent. The purpose this study was to prospectively examine relation between use in men.We examined independent association intake self-reported professionally diagnosed 26,809 men aged 40 74 yrs at baseline 1986. Study participants completed...
Aspirin, nonsteroidal antiinflammatory drugs (NSAID), and acetaminophen are commonly used. Frequent use of analgesics has been associated with a higher risk hearing loss. However, the association between duration analgesic loss is unclear. We investigated relationship self-reported among 55,850 women in Nurses' Health Study. Cox proportional hazards regression was used to adjust for potential confounders. During 873,376 person-years follow-up (1990-2012), longer durations NSAID (for >6 years...
Black individuals have a lower risk of hearing loss than do whites, possibly because differences in cochlear melanocytes. Previous studies suggested that darker-skinned tend to more inner ear melanin, and melanocytes are important generating the endocochlear potential. We investigated relationship between self-reported skin pigmentation by using hair color, tanning ability, reaction prolonged sun exposure as surrogate measures among 49,323 white women Nurses' Health Study. Cox proportional...