A5101885004- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Pediatric health and respiratory diseases
- Bacterial Infections and Vaccines
- Brucella: diagnosis, epidemiology, treatment
- Microbial infections and disease research
- Congenital Diaphragmatic Hernia Studies
- Asthma and respiratory diseases
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Streptococcal Infections and Treatments
- Cancer-related molecular mechanisms research
- Natural Language Processing Techniques
- Topic Modeling
- Respiratory Support and Mechanisms
- Infective Endocarditis Diagnosis and Management
- Autophagy in Disease and Therapy
- Hormonal and reproductive studies
- Bacteriophages and microbial interactions
- Monoclonal and Polyclonal Antibodies Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer Risks and Factors
- Delphi Technique in Research
- Hormonal Regulation and Hypertension
The First Affiliated Hospital, Sun Yat-sen University
2025
Jinzhou Medical University
2025
Curtin University
2025
Sun Yat-sen University
2025
Shanxi Medical University
2025
Children's Hospital of Zhejiang University
2011-2024
South China Agricultural University
2023-2024
Nanjing University of Chinese Medicine
2023
CM Hospital
2023
Southern Medical University
2013-2022
Abstract Background The interplay between COVID‐19 pandemic and asthma in children is still unclear. We evaluated the impact of on childhood outcomes. Methods PeARL multinational cohort included 1,054 with 505 non‐asthmatic aged 4 18 years from 25 pediatric departments, 15 countries globally. compared frequency acute respiratory febrile presentations during first wave groups data available previous year. In asthma, we also current historical disease control. Results During pandemic,...
Abstract Background Viruses are the main infectious agents of acute respiratory infections in children. We aim to describe epidemiological characteristics viral pathogens tract outpatient Methods From April 2018 March 2019, results detection using oral pharyngeal swabs from 103,210 children with infection department Children’s Hospital, Zhejiang University School Medicine, were retrospectively analyzed. Viral antigens, including adenovirus (ADV), influenza A (FLUA), B (FLUB) and syncytial...
Background Chronic diseases among older adults are recognised as a serious public health problem in China, causing rising social and economic burden. The aim of the study was to evaluate association between chronic lifestyle risk factors community-dwelling who attended community service centres (CHSC) Southern China. Methods A retrospective cross-sectional ( n = 361) conducted using random sample cases from primary care database registry two CHSC Guangzhou city, Guangdong province, consisted...
The importance of culturally competent care in multicultural environments is increasingly recognized; however, effective tools to assess nursing students' cross-cultural competence remain limited. This study aimed validate the BENEFITS-CCCSAT for Chinese students. original was translated, back-translated, adapted, and pre-tested using Brislin model form a version. A combined approach classical test theory (CTT) item response (IRT) then used multidimensional validation. CTT analysis showed...
Asthma is a global problem. Prevalence varies among different countries and cities. We aimed to obtain the prevalence, describe characteristics, discover factors that may relate asthma in Hangzhou.This cross-sectional study was conducted Hangzhou. The subjects were children aged 14 years younger. A control group of non-asthma matched age sex with each asthmatic patient also randomly selected interviewed. International Study Allergies Childhood National Epidemiology China questionnaires used...
ABSTRACT Sleep deprivation (SD) has been associated with a plethora of severe pathophysiological syndromes, including gut damage, which recently elucidated as an outcome the accumulation reactive oxygen species (ROS). However, spatiotemporal analysis conducted in this study intriguingly shown that specific events cause harmful damage to gut, particularly goblet cells, before lethal ROS. Transcriptomic and metabolomic analyses have identified significant enrichment metabolites related...
<h3>INTRODUCTION:</h3> This study prospectively evaluated the effect of early bronchoalveolar lavage (BAL) on refractory <i>Mycoplasma pneumoniae</i> pneumonia with radiologically proven large pulmonary lesions in children. <h3>METHODS:</h3> A total 35 children diagnosed as having <i>M. completed study. According to time point BAL, they were divided into 2 groups. In BAL group, was performed within 3 d after admission (<i>n</i> = 22); late later 13). Clinical effects compared between these...
Chondrocyte senescence play an essential role in osteoarthritis (OA) progression. Recent studies have shown that snoRNA-derived RNA fragments (sdRNAs) are novel regulators of post-transcriptional gene expression. However, the expression profiles and their regulation chondrocyte OA progression is unknown. Here, we determined sdRNAs profile explored sdRNA-D43 its mechanism. We used qPCR arrays to determine chondrocytes areas undamaged damaged three knee samples. SdRNA-D43 was using...
Abstract The aim of this study is to investigate the mechanism action and correlation between transforming growth factor beta 1 (TGF-β1) β-catenin in pelvic organ prolapse (POP). compared vaginal wall tissues from two groups: 20 patients with POP (POP group) who had hysterectomies for benign conditions (control group). Hematoxylin Eosin Masson staining visualized collagen, while TUNEL detected apoptosis. Protein mRNA expression levels TGF-β1, β-catenin, matrix metallopeptidase 2 (MMP2),...
Exogenous androgen supplement is an optional treatment for micropenis; however, its use in childhood controversial due to potential side effects.Twenty-three children (mean age: 4.07±3.4 years) with micropenis of unknown causes harboring the 46,XY karyotype were recruited open prospective study. Androgen receptor (AR), steroid 5α-reductase-2 (SRD5A2), and SRY genes sequenced; 2.5% dihydrotestosterone (DHT) transdermal gel (0.1-0.3 mg/kg/day) was applied titrated within normal DHT serum...
The aim of the present study is to investigate rules and characteristics clinical administration traditional Chinese medicine (TCM) in treatment polycystic ovary syndrome (PCOS) using data mining methods.Medical cases well-known contemporary TCM doctors treating PCOS were collected from China National Knowledge Infrastructure, Biomedical Literature Service System, Wanfang, Scientific Journals Database, PubMed; then characterized, a standardized database medical was built. This used (1) count...
ABSTRACT Importance Importance: The interplay between COVID-19 pandemic and asthma in children is still unclear. Objective We evaluated the impact of on childhood outcomes. Design PeARL multinational cohort included with non-asthmatic controls recruited during compared current disease activity data available from previous year. Setting Pediatric outpatient clinics. Participants study 1,054 505 controls, aged 4-18 years, 25 pediatric departments, 15 countries globally. Exposures first wave,...
Streptococcus intermedius , as a Gram-positive commensal bacterium, tends to cause various infections, such brain and liver abscesses, endocarditis, empyema, especially in immunocompromised patients. However, an isolated pulmonary nodule caused by S. previously healthy individuals without traditional risk factors is rarely reported. Herein, we present case of 10-year-old immunocompetent boy referred our department with 5-day history intermittent, left-sided chest pain. Chest X-ray computed...
The Alveolar soft-part sarcoma (ASPS) involving the lung is mostly metastatic, while primary ASPS occurs more rarely. Herein, we reported on another case of ASPS, which might be with earliest onset thus far. In this report, surgery was used to excise lesion as much possible, and its combination chemoradiotherapy anti-angiogenic agent may provide an important reference for development standard treatment or first-line these children patients. This