The vast majority of patients with cancer at the end life receive parenteral hydration in hospitals and no hospice, limited evidence supporting either practice. In this randomized controlled trial, we determined effect on symptoms associated dehydration, quality life, survival advanced cancer.We randomly assigned 129 from six hospices to (normal saline 1 L per day) or placebo 100 mL daily over 4 hours. primary outcome was change sum four dehydration (fatigue, myoclonus, sedation...

Purpose Cancer-related-fatigue (CRF) is common in advanced cancer. The primary objective of the study was to compare effects methylphenidate (MP) with those placebo (PL) on CRF as measured using Functional Assessment Chronic Illness Therapy–Fatigue (FACIT-F) fatigue subscale. effect a combined intervention including MP plus nursing telephone (NTI) also assessed. Patients and Methods cancer score ≥ 4 out 10 Edmonton Symptom Scale (ESAS) were randomly assigned one following four groups:...

Objectives: To determine the effects of thalidomide and placebo on anorexia-cachexia its related symptoms, body composition, resting metabolic rate, serum cytokines their receptors in patients with advanced cancer. Methods: Included study were cancer weight loss greater than 5% 6 months who reported anorexia, fatigue, one following: anxiety, depression, or sleep disturbances. Patients chemotherapy within 2 weeks prior during excluded from study. randomly assigned to either 100 mg once a day...

BACKGROUND Systematic symptom assessment is not routinely performed in pediatric oncology. The objectives of the current study were to characterize symptoms oncology outpatients and evaluate agreement between patient proxy reports association children's ratings oncologists' treatment recommendations. METHODS Two versions Memorial Symptom Assessment Scale (pMSAS) translated into Spanish. An age‐appropriate language‐appropriate pMSAS was administered independently before visits oncologist...

Meeting the preferences of patients is considered an important palliative care outcome. Prior studies reported that more than 80% with terminally ill cancer prefer to die at home. The purpose this study was determine place-of-death preference among in outpatient centre and unit (PCU) a comprehensive centre.A cross-sectional anonymous questionnaire administered advanced caregivers (PCU centre) between August 2012 September 2014. PCU responded when there no delirium primary caregiver patient...

To compare the time duration of self-completion (SC) Edmonton Symptom Assessment Scale (ESAS) by patients with advanced cancer (ACPs) versus assisted completion (AC) a health care professional.In this randomized comparison ACPs seen in initial consultation at outpatient Supportive Care Center MD Anderson, who have never completed ESAS Anderson were allocated (1:1) to either SC form AC nurse. Time was measured nurse using stopwatch. Patients Rapid Estimate Adult Literacy Medicine (REALM) test...

The response to haloperidol as a first-line neuroleptic and the pattern of rotation after failure have not been well defined in palliative care. purpose this study was determine efficacy predictors associated with need rotate second neuroleptic. We conducted retrospective review charts advanced cancer patients admitted our acute care unit between January 2012 March 2013. Inclusion criteria were diagnosis delirium treatment haloperidol. Among 167 delirium, 128 (77%) received only 39 (23%)...

Academic hospitals contribute to health care through patient care, research, and teaching; however, their outcomes may not be equivalent nonacademic hospitals. Multivariate analysis of variance is used compare publicly reported data on satisfaction, readmission rates, mortality hospital-acquired injury scores between 1906 academic hospitals, while controlling for hospital-level covariates. Results show that have higher levels satisfaction 7 the 11 measures are remaining 4 measures. lower...

Abstract Background There is limited evidence about the response of breakthrough pain (BTP) to most commonly used oral immediate-release (IR) opioids. Our aim was determine rate IR opioids for BTP control in patients with advanced cancer. Materials and Methods In this prospective study, palliative care outpatients, cancer adequately managed background pain, were asked complete a self-administered survey. We assessed patients’ baseline demographics, characteristics, alcoholism (CAGE...

Health care professionals may have limited exposure to home-based care. There is no published literature that has described the experiences and satisfaction of participation in patient home visits (PHV).The objective this article describe characteristics PHV, our approach, evaluation by participants over a nine-year period.We conducted review surveys completed PHV from 2005-2013. All anonymously questionnaires at end PHVs. Different assessment forms were used for 2005-2010 2011-2013 time...

9025 Background: The vast majority of cancer patients at the end life receive PH in hospitals and no hospice. There is limited evidence supporting either practice. Our preliminary study suggested that (1L/day) improved dehydration symptoms (Bruera et al. JCO 2005). In this randomized controlled trial, we determined effect on associated with dehydration, quality survival for advanced cancer. Methods: We randomly assigned 129 from 6 hospices to subcutaneous (normal saline 1 L/day) or placebo...

9023 Background: CRF is the most common and distressing symptom in advanced cancer patients. Preliminary studies support MP NTI for (Bruera et al. JCO 2006). The primary objective of our study was to determine effect as compared placebo (P). A secondary investigate role control telephone intervention (CTI). Methods: Advanced patients with fatigue ≥4/10 on Edmonton Symptom Assessment Scale (ESAS), normal cognition, no evidence major depression hemoglobin ≥8 were eligible. Patients randomized...

128 Background: Decreased oral intake is very common at the end of life. Dehydration can aggravate symptoms like fatigue, myoclonus, and confusion. Intravenous (iv) hydration home be uncomfortable expensive. Hypodermoclysis (HDC) a comfortable inexpensive but rarely used way to provide life in setting. The purpose this study was evaluate program HDC by caregivers. Methods: All caregivers underwent 45 minute training session on administration assessment infusion site delivered specially...

TPS238 Background: Advanced cancer patients frequently identify fatigue as the main impairment to quality of life. Fatigue can stem from multiple causes, encompassing physical and psychosocial domains.Prior studies show a high prevalence hypogonadism in males with cancer, particularly those on opioid therapy. Low testosterone levels correlated fatigue, depression, poor appetite, insomnia decreased libido. Currently there are few effective therapies for related fatigue. Symptomatic...

e20612 Background: Supportive Care Outpatient Clinics (SCOC) offer comprehensive care and symptom management to patients with advanced cancer (AdCa). Missed appointments (MA) are frequent but they no studies on the clinical outcomes of who fail show for consultation. Methods: We determined frequency MA, including demographic data, reviewed clinic appointment records 218 consecutive kept (KA) MA distinct referred SCOC from January December 2011. Results: 218/1,352 (16%) AdCa were our SCOC,...

26 Background: The use of electronic health records (EHR) continues to rise in various clinical settings. full effects EHR on physician-patient interactions remain unclear. This study aims compare patient perception physician’s compassion, communication skills, and professionalism between a traditional face clinic visit with where an examination room computer is used by the physician access document information. Methods: RCT was conducted at outpatient supportive care center. 120 English...

67 Background: ESAS is a multidimensional assessment tool for self-reporting of symptom intensity. Unfortunately, not used often in clinical care due to the perception that it may be time consuming. Our aim was compare duration self-completion (SC) first by patients with advanced cancer vs. assisted-completion (AC) health professional (HCP). Methods: In this randomized controlled trial, who have never completed at MD Anderson were allocated (1:1) web-based system either form vs assisted...

9528 Background: Understanding the preferred place of death (POD) for advanced cancer patients (pts) is very important when they are approaching end life. Meeting preferences pts considered an palliative care outcome. Prior studies reported that more than 80% with terminally ill prefer to die at home. In many countries such as UK, Italy, Greece, South Korea and Japan home deaths have been falling, but in some states US/Canada there indications a reversal trends. Dying may be difficult severe...

e20581 Background: Most patients admitted to APCU are transferred from inpatient oncology units. We hypothesized that EC admissions have different symptom burden and outcomes compared IP patients. In this retrospective cohort study, we the survival between groups. Methods: Among all 2,568 our September 1, 2003 August 31, 2008, 312 (12%) were randomly selected 298 as controls. retrieved patient demographics, cancer diagnosis, Edmonton Symptom Assessment Scale (ESAS), discharge outcomes,...