A5042083053- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Spine and Intervertebral Disc Pathology
- Blind Source Separation Techniques
- Musculoskeletal pain and rehabilitation
- Spinal Cord Injury Research
- Spinal Fractures and Fixation Techniques
- Neuroscience and Neural Engineering
- Functional Brain Connectivity Studies
- Advanced Vision and Imaging
- Advanced MRI Techniques and Applications
- Scoliosis diagnosis and treatment
- Remote Sensing and Land Use
- Stroke Rehabilitation and Recovery
- Soft Robotics and Applications
- Advanced Sensor and Energy Harvesting Materials
- Remote Sensing in Agriculture
- Spectroscopy and Chemometric Analyses
- Heart Rate Variability and Autonomic Control
- Cerebral Palsy and Movement Disorders
University of Hong Kong
2016-2025
Chinese University of Hong Kong
2014-2025
University of Hong Kong - Shenzhen Hospital
2016-2025
Zhejiang Chinese Medical University
2025
Sichuan University
2009-2025
Zhongshan Hospital
2002-2025
Chongqing Municipal Health Commission
2016-2025
Guangdong Medical College
2016-2025
Fudan University
2017-2025
Anhui Medical University
2012-2025
Subtypes are widely found in cancer. They characterized with different behaviors clinical and molecular profiles, such as survival rates, gene signature copy number aberrations (CNAs). While cancer is generally believed to have been caused by genetic aberrations, the of events tremendous tissue only a small subset them may be tumorigenic. On other hand, expression subtype represents residuals subtype-specific mechanisms. Using high-throughput data link these factors define boundaries...
Abstract Here we report corin, a synthetic hybrid agent derived from the class I HDAC inhibitor (entinostat) and an LSD1 (tranylcypromine analog). Enzymologic analysis reveals that corin potently targets CoREST complex shows more sustained inhibition of activity compared with entinostat. Cell-based experiments demonstrate exhibits superior anti-proliferative profile against several melanoma lines cutaneous squamous cell carcinoma to its parent monofunctional inhibitors but is less toxic...
The diagnosis of early stages Alzheimer's disease (AD) is essential for timely treatment to slow further deterioration. Visualizing the morphological features AD great clinical value. In this work, a novel multidirectional perception generative adversarial network (MP-GAN) proposed visualize indicating severity patients different stages. Specifically, by introducing mapping mechanism into model, MP-GAN can capture salient global efficiently. Thus, using class discriminative map from...
Hybrid potato breeding will transform the crop from a clonally propagated tetraploid to seed-reproducing diploid. Historical accumulation of deleterious mutations in genomes has hindered development elite inbred lines and hybrids. Utilizing whole-genome phylogeny 92 Solanaceae its sister clade species, we employ an evolutionary strategy identify mutations. The deep reveals genome-wide landscape highly constrained sites, comprising ∼2.4% genome. Based on diploid diversity panel, infer 367,499...
Aflatoxin B1 (AFB1) has been postulated to be a hepatocarcinogen in humans, possibly by causing p53 mutations at codon 249. AFB1 is metabolized via the phase I and II detoxification pathways; hence, genetic variation those loci may predict susceptibility effects of AFB1. To test this hypothesis, two genes, epoxide hydrolase (EPHX) glutathione S-transferase M1 (GSTM1), was contrasted with presence serum AFB1-albumin adducts, hepatocellular carcinoma (HCC), 249 mutations. Mutant alleles both...
In this paper, the distributed <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">H</i> <sub xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> filtering problem is addressed for a class of polynomial nonlinear stochastic systems in sensor networks. For Lyapunov function candidate whose entries are polynomials, we calculate its first- and second-order derivatives order to facilitate use Itô's differential rule. Then, sufficient condition existence...
The fatigue that users suffer when using steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs) can cause a number of serious problems such as signal quality degradation and system performance deterioration, users’ discomfort even risk photosensitive epileptic seizures, posing heavy restrictions on the applications SSVEP-based BCIs. Towards alleviating fatigue, fundamental step is to measure evaluate it but most existing works adopt self-reported questionnaire...
Diabetic retinopathy (DR) is one of the major causes blindness. It great significance to apply deep-learning techniques for DR recognition. However, algorithms often depend on large amounts labeled data, which expensive and time-consuming obtain in medical imaging area. In addition, features are inconspicuous spread out over high-resolution fundus images. Therefore, it a big challenge learn distribution such features. This article proposes multichannel-based generative adversarial network...
Transient painful stimuli could induce suppression of alpha oscillatory activities and enhancement gamma that also be greatly modulated by attention. Here, we attempted to characterize changes in cortical during tonic heat pain perception investigated the influence directed/distracted attention on these responses. We collected 5-minute long continuous Electroencephalography (EEG) data from 38 healthy volunteers four conditions presented a counterbalanced order: (A) resting condition; (B)...
Soft robotics is quickly emerging in anthropomorphic robotic hand design, with innovative soft robot hands reported to achieve a remarkably large subset of human dexterity, despite their substantially lower mechanistic sophistication compared conventional rigid or underactuated hands. More interestingly, were most successful reproducing object grasping, rather than in-hand manipulation tasks. Inspired by this notable advance, paper investigated the approach, on influence passive compliance...
Grasping is an important characteristic of robots in interacting with humans and the environment. Due to inherent compliance soft grippers, they can easily adapt novel objects operate safely a human-centered However, hands suffer from poor grasping robustness operation durability, especially for heavy or sharp spikes, mainly due their fragile material low structural stiffness actuators. Thus, widespread use daily applications still limited. Existing works have shown promising direction...
Extracting damage information of buildings after an earthquake is crucial for emergency rescue and loss assessment. Low-altitude remote sensing by unmanned aerial vehicles (UAVs) has unique advantages. In this study, we establish a information-extraction method that combines ultramicro oblique UAV infrared thermal imaging technology to automatically detect the structural cracks in external walls. The consists four parts: (1) 3D live-action modeling building structure analysis based on...
Soft robotic glove with brain computer interfaces (BCI) control has been used for post-stroke hand function rehabilitation. Motor imagery (MI) based BCI aided devices demonstrated as an effective neural rehabilitation tool to improve function. It is necessary a user of MI-BCI receive long time training, while the usually suffers unsuccessful and unsatisfying results in beginning. To propose another non-invasive paradigm rather than MI-BCI, steady-state visually evoked potentials (SSVEP) was...