A5041135386- Chromosomal and Genetic Variations
- Genomics and Phylogenetic Studies
- Genomics and Chromatin Dynamics
- Antimicrobial Peptides and Activities
- Lipid Membrane Structure and Behavior
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Immune Response and Inflammation
- Aquaculture disease management and microbiota
Salk Institute for Biological Studies
2022-2025
University of Southern California
2023-2024
Gene Therapy Laboratory
2022
Higher-order chromatin structure and DNA methylation are critical for gene regulation, but how these vary across the human body remains unclear. We performed multi-omic profiling of 3D genome 86,689 single nuclei 16 tissues, identifying 35 major 206 cell subtypes. revealed extensive changes in CG non-CG almost all types characterized at an unprecedented cellular resolution. Intriguingly, discrepancies exist between delineated by structure, indicating that role distinct epigenomic features...