- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Essential Oils and Antimicrobial Activity
- Nanoparticles: synthesis and applications
- Wound Healing and Treatments
- Oral microbiology and periodontitis research
- Mycotoxins in Agriculture and Food
- Antimicrobial agents and applications
- Electrospun Nanofibers in Biomedical Applications
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Nanocomposite Films for Food Packaging
- Phytochemistry and Biological Activities
- Medicinal Plants and Neuroprotection
- Probiotics and Fermented Foods
- Wheat and Barley Genetics and Pathology
- Plant Pathogens and Resistance
- Parasitic Infections and Diagnostics
- Bee Products Chemical Analysis
- Parasitic infections in humans and animals
- Plant Disease Resistance and Genetics
- Advanced Drug Delivery Systems
- Pineapple and bromelain studies
- Quantum Dots Synthesis And Properties
- Plant chemical constituents analysis
Shiraz University of Medical Sciences
2019-2025
Tehran University of Medical Sciences
2020
Abstract In recent years, mesoporous silica nanoparticles (MSNs) have been applied in various biomedicine fields like bioimaging, drug delivery, and antibacterial alternatives. MSNs could be manufactured through green synthetic methods as environmentally friendly sustainable synthesis approaches, to improve physiochemical characteristics for biomedical applications. the present research, we used Rutin (Ru) extract, a biocompatible flavonoid, reducing agent nonsurfactant template of...
Abstract The antifungal efficacy and cytotoxicity of a novel nano-antifungal agent, the Fe 3 O 4 @SiO 2 /Schiff-base complex Cu(II) magnetic nanoparticles (MNPs), have been assessed for targeting drug-resistant Candida species. Due to rising issue fungal infections, especially candidiasis, resistance traditional antifungals, there is an urgent need new therapeutic strategies. Utilizing Schiff-base ligands known their broad-spectrum antimicrobial activity, /Schiff-base/Cu(II) MNPs...
Antimicrobial resistance (AMR) presents a critical global health issue, necessitating novel therapeutic strategies to manage bacterial and fungal infections. This study explores the development evaluation of multifunctional Fe3O₄@SiO₂/Schiff-base/Zn (II) magnetic nanocomposite (MNC) with enhanced antimicrobial properties. The synthesized MNC combines characteristics Fe₃O₄ nanoparticles (MNPs) properties Schiff-base ligand functionalized Zn ions. preparation involved coprecipitation Fe₃O₄,...
The development of novel antifungal agents and, in particular, the widespread use these medications over course past two decades, has had a significant impact on treatment fungal infectious diseases. This resulted complete transformation However, antibiotic resistance masked significance such breakthroughs. Antifungal infection with nanoparticles been shown to be effective. As result their unique characteristics, substances, contrast antibiotics purest form, are able exhibit an increased...
(I) Preparation of deep eutectic solvent. (II) Extraction process.
Clonal expansion of fluconazole resistant (FLZ-R) Candida parapsilosis isolates is increasingly being identified in many countries, while there no study exploring the antifungal susceptibility pattern, genetic diversity, and clinical information for Iranian C. blood isolates. species complex (n=98) were recovered from nine hospitals located three major cities, by MALDI-TOF MS, their relatedness was examined AFLP fingerprinting. Antifungal testing followed CLSI-M27-A3 ERG11, MRR1 hotspots 1/2...
Aims. This study aimed to evaluate the effect of 2.5% and 7.5% copper oxide (CuO) titanium dioxide (TiO2) nanoparticles on antimicrobial activity thermocycled polymethyl methacrylate (PMMA) denture base material against standard strains yeast bacteria species. Material Methods. In this in vitro study, 150 disk-shaped (10 × 2 mm) specimens heat-cured PMMA were prepared divided into five groups (n = 30) be reinforced with CuO, TiO2, or TiO2 a control group (without nanoparticle). The...
Objectives. Soft denture liners provide a favorable environment for adhesion and colonization of microorganisms. This in vitro study aimed to examine the efficacy different concentrations copper oxide nanoparticles (CuO NPs) incorporation into soft liner on biofilm formation microbial species. Methods. Field Emission Scanning Electron Microscopy (FESEM) images from NPs were recorded. Antifungal susceptibility testing CuO against five standard strains Candida albicans (CBS 10261, 1905, 1912,...
Background. Spices are one of the flavoring components food in cooking recipes different nations that used daily. However, these ingredients may be contaminated by toxicogenic fungi and subsequent production mycotoxins cannot neutralized through cooking. In present study, possible contamination spices aflatoxins (AFs) ochratoxin A (OTA) was investigated from Shiraz, south part Iran. Materials Methods. total 80 spice samples including turmeric (n = 20), red pepper black cinnamon 20) were...
The fungal contamination and total aflatoxins (AF) ochratoxin A (OTA) of tea samples were examined. 60 extracted treated with immunoaffinity columns. amount AF OTA determined by using high-performance liquid chromatography (HPLC) a fluorescence detector (FD). Tea cultured the fungi identified. results showed that 24 (40%) contaminated AFs none above acceptable limit (≥10 μg/kg). All where only 3 black (6.6%) 1 green sample (6.7%) detected to have more than standard limits toxin (10 μg·kg-1)....
Superficial and cutaneous fungal infections are common in tropical areas. The aim of this study was to provide a basic database superficial mycoses the most etiological agents among patients.Between 2015 2019, total 1807 patients suspected mycosis referring mycology laboratory Shiraz medical school, Fars, Iran were evaluated. Specimens taken from patients' affected area, clinical samples examined by direct microscopy culture. epidemiological profile collected.A 750 confirmed with mycoses....
The performance of drug‐loaded electrospun mats as novel wound dressings is substantially affected by their formulation. In this study, the influence polymer and drug concentration on microstructure, mechanical properties, release behavior well biological characteristics poly(vinylidene fluoride) (PVDF) loaded with Zataria multiflora essential oil (ZMEO) an herbal explored. From microstructural, mechanical, processability viewpoints, blank obtained from solution 14 wt.% PVDF had optimum...