A5023562799- Dialysis and Renal Disease Management
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Parathyroid Disorders and Treatments
- Chronic Kidney Disease and Diabetes
- Central Venous Catheters and Hemodialysis
- Diet and metabolism studies
- Muscle and Compartmental Disorders
- Renal function and acid-base balance
- Vitamin K Research Studies
- Neurological and metabolic disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Eicosanoids and Hypertension Pharmacology
- Diabetes and associated disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Function and Risk Factors
- Vitamin C and Antioxidants Research
- Nutritional Studies and Diet
- Metabolism and Genetic Disorders
- Myasthenia Gravis and Thymoma
- Metabolism, Diabetes, and Cancer
- Alcohol Consumption and Health Effects
- Alcoholism and Thiamine Deficiency
- Hormonal Regulation and Hypertension
- Cardiovascular Disease and Adiposity
University Hospital of Alexandroupolis
2011-2024
AHEPA University Hospital
2019-2023
Aristotle University of Thessaloniki
2019-2023
IberEspacio (Spain)
2021
Democritus University of Thrace
2011-2020
St Savas Hospital
2000
Background: Intima-Media-Thickness of the carotid artery wall (cIMT) is a strong predictor cardiovascular (CV) disease. The aim this study was to investigate significance cIMT as an independent prognostic factor for CV morbidity and mortality in patients with chronic kidney disease (CKD) diabetes mellitus type 2 (DM2).Methods: included 142 diabetic different stages CKD. Patients were categorized into two groups according low (≤0.86 mm) or high (>0.86 mm), respectively. events death from all...
We aimed to investigate the possible association of inactive, dephosphorylated, uncarboxylated matrix Gla protein (dp-ucMGP) with oxidized low-density lipoprotein (ox-LDL) and all-cause/cardiovascular (CV) mortality renal function in diabetic chronic kidney disease (CKD). Ox-LDL dp-ucMGP were determined 66 CKD patients. All patients prospectively followed for seven years, or until occurrence death, a composite outcome 30% estimated glomerular filtration rate (eGFR) reduction progression...
Background: This study aimed to investigate the effects of a home-based exercise training program on Cardiac Autonomic Neuropathy (CAN) and metabolic profile in Diabetic Kidney Disease (DKD) patients undergoing maintenance hemodialysis (HD). Method: Twenty-eight DKD were randomly assigned into two groups. The (EX) group followed 6-month combined at home, while control (CO) remained untrained. All participants baseline end underwent cardiopulmonary testing (CPET), biochemical tests for...
Diabetic type 2 patients compared to nondiabetic exhibit an increased risk of developing diabetic kidney disease (DKD), the leading cause end-stage renal disease. Hyperglycemia, hypertension, oxidative stress (OS), and genetic background are some mechanisms pathways implicated in DKD pathogenesis. However, data on OS pathway susceptibility genes show limited success conflicting or inconclusive results. Our study is aimed at exploring variants which could be associated with DKD. We recruited...
Background: Hemodiafiltration with online preparation of the substitution [online high-flux hemodiafiltration (OHDF)] and prepared bags (HDF) are important, recently widely used renal replacement therapies in patients end-stage disease. However, there is little information on comparative impacts these modalities versus conventional low-flux hemodialysis (HD) quality life (QoL) HD patients. This study investigates effect dialysis modality QoL chronic Methods: In this prospective, randomized,...
Aims . We sought to determine the association between levels of adiponectin and oxidized low-density lipoprotein (ox-LDL) in patients with diabetic nephropathy as well their effect on carotid intima-media thickness (cIMT). Methods Adiponectin ox-LDL were determined 25 without 94 at different stages including subjects hemodialysis. cIMT was measured using real-time B-mode ultrasonography. Results Plasma increased significantly severity (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Soluble epoxide hydrolase 2 (EPHX2) is an enzyme promoting increased cellular apoptosis through induction of oxidative stress (OS) and inflammation. The EPHX2 gene which encodes soluble might be implicated in the pathogenesis development OS atherosclerosis. We aimed to assess possible association between two functional polymorphisms (rs2741335 rs11780592) with oxidized LDL (ox‐LDL), carotid atherosclerosis, mortality, cardiovascular (CV) disease 118 patients diabetic chronic kidney (CKD). At...
Diabetic kidney disease (DKD) is a highly heterogenous disease, including the proteinuric and nonproteinuric pattern. Oxidized low‐density lipoprotein (ox‐LDL) progressively increased in DKD causes direct damage to tubular epithelial cells through mechanism similar that underlying deleterious effect of lipid peroxides vascular endothelium. We aimed examine association between plasma ox‐LDL cholesterol clinical endpoints patients. Ninety‐one patients with established diabetic retinopathy were...
We sought to investigate the possible association between Red Blood Cell Distribution Width (RDW), vascular calcification, oxidative stress and renal function all-cause/cardiovascular (CV) mortality, CV events progression of kidney disease in a cohort patients with Diabetic Kidney Disease (DKD). Carotid intima media thickness (cIMT) oxidized low-density cholesterol were measured 104 Type 2 Diabetes Mellitus (T2DM) established DKD, distributed all five stages 38 diabetics normal function. All...
Proteinuria is characterized by low accuracy for predicting onset and development of diabetic kidney disease (DKD) because it not directly associated with molecular changes that promote DKD, but a result damage. Oxidized low-density lipoprotein (ox-LDL) reflects oxidative stress endothelial dysfunction, both underlying the proteinuria loss function in DKD. We aimed to investigate whether ox-LDL modifies association between progression DKD cohort 91 patients proteinuric retinopathy, followed...
Background: Calcific uremic arteriolopathy is an uncommon cutaneous ischemic necrotizing disease, most commonly associated with renal disease and hyperparathyroidism, bearing a high mortality rate. Objective Method: A case of 57-year-old female patient hyperparathyroidism who was successfully treated combined paricalcitol cinacalcet systemically, while autologous growth factors were locally applied, herein presented. Result Conclusion: The combination reliable alternative to...
Background: Approximately one third of type 2 diabetes mellitus (T2DM) cases present with diabetic nephropathy (DN), the leading cause end-stage renal disease. Inflammation plays an important role in T2DM disease and DN pathogenesis. NLRP3 inflammasomes are complexes that regulate interleukin-1B (IL-1B) IL-18 secretion, both involved inflammatory responses. Activation is associated onset progression. Here, we explore whether variants genes encoding key members inflammasome pathway. Methods:...