A5003624585- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Clostridium difficile and Clostridium perfringens research
- Nosocomial Infections in ICU
- Neonatal and Maternal Infections
- Antibiotic Resistance in Bacteria
- Infectious Diseases and Tuberculosis
- Antibiotics Pharmacokinetics and Efficacy
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Bacterial Infections and Vaccines
- Healthcare cost, quality, practices
- Genetics, Bioinformatics, and Biomedical Research
- Health Promotion and Cardiovascular Prevention
- Respiratory and Cough-Related Research
- Syphilis Diagnosis and Treatment
- Antimicrobial Resistance in Staphylococcus
- Obesity and Health Practices
- Microscopic Colitis
- Reproductive tract infections research
National Institute of Allergy and Infectious Diseases
2025
National Institutes of Health
2024
National Institutes of Health Clinical Center
2023-2024
Government of the United States of America
2024
University of California, San Diego
2019-2023
University of San Diego
2022
VA San Diego Healthcare System
2020
Museum of Heilongjiang Province
2020
Spectrum Health
2019
Abstract Objective: Lack of judicious testing can result in the incorrect diagnosis Clostridioides difficile infection (CDI), unnecessary CDI treatment, increased costs and falsely augmented hospital-acquired (HAI) rates. We evaluated facility-wide interventions used at VA San Diego Healthcare System (VASDHS) to reduce healthcare-onset, healthcare-facility–associated (HO-HCFA CDI), including use diagnostic stewardship with test ordering criteria. Design: conducted a retrospective study...
Abstract Objective: Medical residents are an important group for antimicrobial stewardship programs (ASPs) to target with interventions aimed at improving antibiotic prescribing. In this study, we compared prescribing practices of 2 academic medical teams receiving different ASP training approaches along a hospitalist control group. Design: Retrospective cohort study comparing guideline-concordant 3 common infections among family medicine (FM) resident service, internal (IM) and...
Antimicrobial resistance (AMR) surveillance in low- and middle-income countries (LMICs) often relies on poorly resourced laboratory processes. Centralized sequencing was combined with cloud-based, open-source bioinformatics solutions for national AMR Cambodia.
Despite concerns regarding the increasing obesity epidemic, little is known curricula in medical education. Medical school family medicine clerkships address common primary care topics during clinical training. However, studies have shown that many physicians feel unprepared at addressing obesity. The purpose of this study was to evaluate factors related education provided as well identify future plans Data were collected through 2017 Educational Research Alliance (CERA) survey Family...
Abstract Disseminated gonococcal infection (DGI) often manifests as arthritis and may carry significant morbidity. However, diagnosis remains elusive due to limited sensitivity of available diagnostic tests. We used metagenomic next-generation sequencing detect Neisseria gonorrhoeae from culture-negative joint aspirates 2 patients with clinically diagnosed DGI.
Background: Antimicrobial resistance (AMR) surveillance in low- and middle-income countries (LMICs) often relies on poorly resourced laboratory processes. In this pilot study, a centralized sequencing workflow was combined with cloud-based, open-source bioinformatics solutions as part of national AMR Cambodia. Methods: Blood cultures positive for gram-negative bacteria were collected at six Cambodian hospitals (January 2021 – October 2022). Isolates obtained from pure plate growth DNA...
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Data on antimicrobial resistance (AMR) and association with outcomes in resource-variable intensive care units (ICU) are lacking. currently available limited to large, urban centers. We attempted understand this locally through a dual-purpose, retrospective study. Cohort A consisted of adult pediatric patients who had blood, urine, or cerebrospinal fluid cultures obtained from 2016 2020. total 3,013 isolates were used create the Kijabe Hospital's first antibiogram. Gram-negative organisms...
An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.
Background: Clostridioides difficile infection (CDI) accounts for >500,000 community-, nursing-, and hospital-acquired infections (HAIs), as well 15,000–30,000 deaths, =$4.8 billion in the United States annually. C. toxin B gene nucleic acid amplification testing (NAAT) cannot distinguish between active CDI colonization, particularly setting of laxative use or enteral feeding. Lack judicious can result incorrect diagnosis CDI, unnecessary treatment, increased costs, falsely augmented HAI...
Abstract Background Antimicrobial resistance is a pressing global health issue. Data are lacking in detailing the presence and burden of antimicrobial low middle-income countries. What currently available quarantined to large, urban centers away from rural facilities. Methods This was retrospective descriptive study performed at Kijabe Hospital, 350-bed teaching hospital, February 2016 September 2020. Cultures blood, urine, cerebrospinal fluid were included all pediatric adult patients....
Abstract Background Osteoarticular infections (OAI) account for 10-20% of extrapulmonary Mycobacteria tuberculosis (MTB) complex in children. Given the rarity MTB OAI, epidemiology, disease manifestations, and treatment are poorly characterized. We describe 21 children treated OAI over a 26-year period at tertiary pediatric center southern California. Methods conducted retrospective review diagnosed with cared between 31 Dec 1992 to 2018 single care hospital close proximity United...