In the present study, role of gonadectomy on memory impairment and density androgen receptor-immunoreactive neurons in rats' hippocampus as well ability testosterone to compensate receptors was evaluated. Adult male rats (except intact-no group) were bilaterally castrated, behavioral tests performed 2 weeks later. Animals cannulated into lateral ventricles then received (10, 40 120 µg/0.5 µl DMSO) or vehicle (DMSO; 0.5 µl) for gonadectomized-vehicle group, 30 min before training water maze...

This study deals with effects of different salinities on the survival, growth, reproductive and lifespan characteristics three Artemia populations from Urmia Lake small lagoons at vicinity lake under laboratory conditions. Experimental ranged 75 to 175 g L(-1). Salinity was proved have significant impact majority characters studied in this survey. Growth survival bisexual A. urmiana parthenogenetic were significantly higher respect most tested. Reproductive such as total number broods,...

Alzheimer's disease (AD) is a neurodegenerative disorder associated with decline in memory deficits and neuropathological diagnosis loss of cholinergic neurons the brains older adults. Based on these facts an increasing number involved people worldwide, this investigation aimed to study improvement cognitive impairments via anticholinergic approach thiazolidine-2,4-diones (TZDs) scopolamine-induced model Alzheimer type adult male Wistar rats (n = 40). The results indicated data analysis...

Background: Alzheimer’s disease (AD) is one of the most common neurodegenerative syndromes characterized by a progressive decline in spatial memory. There are convincing evidences on neuroprotective effects flavonoids against AD. Aims and Objective: To determine effect quercetin acquisition retention memory rat model AD. Materials Methods: Twenty-four male Wistar rats were divided into four groups (six each): group I: control receiving intracerebroventricular (ICV) injection normal...

Autism is a complicated neurodevelopmental disorder characterized by several behavioral impairments. The pathology of autism complex and not fully known. Several recent studies have shown alterations in the activities antioxidant enzymes autism. Vitamin C potent that present high concentrations brain acts as neuromodulator. Prefrontal abnormality has been hypothesized to underlie autistic symptoms. study investigated protective effect prenatally on autistic-like behaviors, oxidative stress...

The present study aimed at assessing the effects of exposure to silver nanoparticle (AgNP) and a subsequent acute stress on expression various genes involved in hypothalamus-pituitary-interrenal (HPI) axis zebrafish, Danio rerio. fish were exposed 0 (Control), 0.1 (LC), 0.4 (MC), 1.2 (HC) mg Ag/L (as AgNP) over 2-week period, followed by an air stress. whole body cortisol selected brain kidney analyzed, before after results showed that AgNP increased basal levels corticotropin releasing...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Sayyahi A, Jahanshahi M, Amini H, Sepehri H. Vitamin E can compensate the density of M1 receptors in hippocampus scopolamine-treated rats. Folia Neuropathologica. 2018;56(3):215-228. doi:10.5114/fn.2018.78703. APA Sayyahi, A., Jahanshahi, M., Amini, H., & Sepehri, (2018). Neuropathologica, 56(3), 215-228. https://doi.org/10.5114/fn.2018.78703 Chicago Ali, Mehrdad Hossein and Hamid Sepehri. 2018. "Vitamin rats"....

Background: Aging process is often accompanied with some degree of decline in all the abilities, including learning and memory. One attracting research fields has been devoted to finding antiaging drugs. Metformin shown memory-enhancing features aged humans laboratory animals. Aims Objective: To evaluate effects 50, 75, 100 mg/kg metformin on spatial memory performance rats Morris water maze. Materials Methods: Thirty-two male 24-month-old were divided randomly into four groups (n = 8)...

The classical renin-angiotensin system (RAS) has an important role in the cardiovascular and water homeostasis body. Recently, existence of RAS with all its components been shown mammalian brain. participates many brain activities, including memory acquisition consolidation. Since cholinergic neurotransmission hippocampus is crucial for these functions, this study aims to evaluate hippocampal angiotensin receptors (ATs) choline acetyltransferase (ChAT) mRNA renovascular hypertensive rats...

Momordica charantia or bitter melon is a tropical vine of the family Cucurbitaceous widely grown in India. Its fruits have potent anti-oxidant properties due to presence tannins, vitamin C and flavonoids. There much evidence it protects cognitive function cholesterol level. In addition, there are reports effect high-fat diet (HFD)on memory. this study, on spatial memory rats, following an HFD, water maze was examined.In 28 male Wistar rats aged 10 weeks weighing between 180 250 grams were...

The study aimed to assess the effect of simvastatin on gene expression LDLR, SREBPs, and SCD1 in rat hepatic tissues fed with high-fat diets (HFD) its association some biochemical parameters. Thirty-two male Wister albino rats were divided into four equal groups (three test one control groups). parameters determined by using spectrophotometer techniques Elisa method. Low-density lipoprotein receptor, sterol regulatory element-binding proteins, stearoyl-CoA desaturase1, Beta-actin analysed...

Previous work has shown that various plant extracts administered to animals stimulate milk protein synthesis through the secretion of prolactin. It also been beta-glucan and pectin are active molecules capable stimulating prolactin release in vivo after intravenous injections. In this work, it is several derivatives able from hypophysis fragments incubated for 2 hr a synthetic medium.

Background: Apart from functioning as a multimodal hematopoietic growth factor, granulocyte colony-stimulating factor (G-CSF) causes intense consequences on the brain. It has been viewed that G-CSF boosts improvement neurologic deficits in rodent models of central nervous system diseases. Aims and Objective: To evaluate efficacy an intervention for improving cognitive commonly associated with aging. Materials Methods: In this study, male Wistar rats aged 21 months were treated 2 weeks...

Introduction: Autism spectrum disorder (ASD) is a disabling psychiatric disease characterized by impairments in communication and social skills. The pathophysiology of autism complex not fully known. Considering the incidence sleep disorders individuals with ASD important role orexin sleep, it possible to hypothesize that an alteration orexinergic system could be implicated pathogenesis symptoms. present study was conducted investigate effect suvorexant [dual receptor antagonists (DORAs)] on...

Background: Filgrastim is a granulocyte colony-stimulating factor (G-CSF), which also showed effects on memory and cognation. Although recent studies have begun to explore G-CSF-related mechanisms of action in memory, little known about its cholinergic system. Since the system has key role some reported G-CSF activity. Choline acetyltransferase (ChAT) acetylcholinesterase (AChE) gene expression was examined rat frontal cortex hippocampus. Aims Objectives: This study designed investigate...

The present study was formulated in order to evaluate the effect of gavage walnut oil enriched with different doses a phytosterol, i.e. β-sitosterol (30, 45 and 60 mg kg−1) on liver tissue diabetic rats. Walnut extracted through cold press method analyses were performed by gas chromatography (GC) high-performance liquid (HPLC). Determination carried out staining via three protocols, hematoxylin eosin (H&E stain), trichrome, terminal deoxynucleotidyl transferase dUTP nick end labeling...