The aim of this study was to find out if occupational exposure dust, fumes or gases, especially among never-smokers, increased the mortality from chronic obstructive pulmonary disease (COPD). A cohort 317,629 Swedish male construction workers followed 1971 1999. Exposure inorganic dust (asbestos, man-made mineral fibres, cement, concrete and quartz), gases irritants (epoxy resins, isocyanates organic solvents), (asphalt fumes, diesel exhaust metal fumes), wood based on a job-exposure matrix....

The aim of the present study was to assess association between socio-economic status and impaired respiratory health in a 10-yr follow-up population-based postal survey Northern Sweden. Multiple logistic regression used estimate odds ratios relation class, using age, sex, family history asthma, smoking habits, occupational exposures dust, gases fumes as possible confounders. comprised 2,341 males 2,413 females. Cumulative incidences were generally lowest professionals, including executives...

Aims: This study compared serum metabolites of demented patients (Alzheimer's disease and vascular dementia) controls, explored metabolite profiles nondemented individuals 5 years preceding the diagnosis. Methods: Cognitively healthy participants were followed up for 5-20 years. Cognitive assessment, sampling, diagnosis completed every Multivariate analyses conducted on generated by gas chromatography/time-of-flight mass spectrometry. Results: A significant group separation was found between...

Objectives Exposure to monoterpenes (I-pinene, J-pinene and q3-carene) in joinery shops was studied Sweden during the processing of Scot's pin acute respiratory effects among employees were evaluated. Methods A cross-sectional study 38 workers carried out 4 shops. The investigation included personal air sampling monoterpenes, biological monitoring metabolites I-pinene workers' urine, interviews following a standardized questionnaire, dynamic spirometry. Results exposure 10--214 mg/m3....

Exposure to trichloramine (NCl(3)) in indoor swimming-pool environments is known cause mucous membrane irritation, but if it gives rise changes lung function or asthma adults not known. (1) We determined volunteers before and after exposure pool environments. (2) studied the occurrence of respiratory symptoms a cohort workers. DESIGN/METHODS/PARTICIPANTS: two groups volunteers, 37 previously non-exposed healthy persons 14 workers, who performed exercise for 2 h an environment. NCl(3) air was...

Objectives This study was performed to evaluate exposure terpenes in sawmills and the acute effects on lung function respiratory tract of exposed laborers. Methods The relationships between personal sawing fumes, assessed by air sampling, terpene metabolites urine were studied. association studied for 48 workers. reactivity methacholine within population investigated. Variation subjective symptoms during a workshift evaluated interviewing employees before after work, following standardized...

Diisocyanates are a group of chemically reactive agents, which used in the production coatings, adhesives, polyurethane foams, and parts for automotive industry as curing agents cores foundry industry. Dermal inhalation exposure to methylene bisphenyl isocyanate (MDI) is associated with respiratory sensitization occupational asthma. However, limited research has been performed on quantitative evaluation dermal MDI occupationally exposed workers. The objective this was quantify levels iron...

By-products of water disinfectants have been suggested to cause asthma, especially in atopic children. However, studies on indoor swimming pool attendance and asthma children presented conflicting results. The present study examined the relationship between among sensitized non-sensitized aged 11-12 years. An extended ISAAC questionnaire was sent families all attending fifth or sixth grade, years, two municipalities Northern Sweden 2010. A total 1866 participated (96% those invited) 1652...

Personnel in swimming pool facilities typically experience ocular, nasal, and respiratory symptoms due to water chlorination consequent exposure disinfection by-products the air. The aim of study was investigate trichloramine trihalomethanes (chloroform, bromodichloromethane, dibromochloromethane, bromoform) from perspective adverse health effects on personnel at Swedish habilitation rehabilitation pools. included 10 nine cities. population comprised 24 exposed workers 50 unexposed office...

Workplace dermal exposure assessment is a complex task that aims to understand the dynamic interaction between skin and hazardous substances present in surrounding environment. A European project known as RISKOFDERM gathered data 85 workplaces (industrial other types) five countries Europe. In order optimize collection develop representative picture of exposure, scenarios (tasks made up series activities) were grouped together into operation units (DEOs). The allocation relevant DEOs was...

Epidemiological studies have shown an increased incidence of cancer among workers occupationally exposed to polycyclic aromatic hydrocarbons (PAHs). As the dermal route is considered important for exposure PAHs in workplace, aim this study was develop and evaluate a tape-stripping technique monitoring pyrene benzo(a)pyrene. The method evaluated by applying different concentrations benzo(a)pyrene directly onto tape strips (spiked tapes), clean glass plates, on skin five volunteers. plates...

A small-scale field trial in Umeå, Sweden with Ogawa samplers and a chemiluminescence instrument indicated that the NO2 concentration was underestimated respect to reference monitor, if calculated according manufacturer's sampling protocol. By co-locating monitors at six sites two Swedish cities, uptake rates were determined for NOx better applicable conditions climate. The concentrations of instruction manual sampler using field-determined compared values derived from each week over which...

Chlorination is a method commonly used to keep indoor swimming pool water free from pathogens. However, chlorination of pools produces several potentially hazardous by-products as the chlorine reacts with nitrogen containing organic matter. Up till now, exposure assessments in have relied on stationary measurements at poolside, proxy for personal exposure. fixed locations are known differ Eight public facilities four Swedish cities were included this survey. Personal and sampling was...

The main aim of the study was to measure exposure monoterpenes (alpha- and beta-pinene Delta(3)-carene) wood dust during industrial production pellets briquettes. Additional aims were compare results from sampled on a filter with real time measurements using direct reading instrument identify peak exposures dust. Twenty-four men working at six companies involved in briquettes participated study. Monoterpenes measured by diffusive sampling as total A data logger (DataRAM) used for continuous...

The main aim of this study was to investigate exposure airborne substances that are potentially harmful health during the production wood pellets, including dust, monoterpenes, and resin acids, as an indicator diesel exhaust nitrogen dioxide. In addition, area measurements were taken assess background levels these substances, volatile organic compounds (VOCs), carbon monoxide. Measurements at four pellet plants from May 2004 April 2005. Forty-four workers participated in study, a total 68...

Objectives Lung cancer caused by radon in miners is a well-known risk. However, the risk estimates vary between studies and mines. We have studied dose response–relationship Swedish iron ore mine where two other previously reached different estimates. As this has relatively low levels, results are highly relevant for estimation non-uranium underground Methods A new cohort of 5486 male workers employed from 1923 to 1996 was established. Cumulative exposures were assessed based on large number...

Objectives Studies of underground miners have documented an increased risk lung cancer mainly linked to radon exposure but possibly influenced by other concurrent exposures. Methods A cohort study was carried out in 8321 iron ore with low radon, employed 1923–1998 and followed up for 1958–2000. Historical exposures crystalline silica diesel exhaust were assessed. Data including quartz from another mine higher reanalysed. Results Miners had (SIR 1.48 (95% CI 1.22 1.78), based on 112 cases...

Trichloramine exposure in indoor swimming pools has been suggested to cause asthma children. We aimed investigate the risk of onset among children relation individual trichloramine exposure.A longitudinal nested case-control study 337 with (cases) and 633 controls aged 16-17 years was performed within a population-based cohort from The Obstructive Lung Disease Northern Sweden studies (OLIN). Year time at different ages were obtained telephone interviews. concentrations pool buildings...

The purpose of the present investigation was to study bronchial responsiveness and pulmonary function in Swedish sawmill workers, who are not exposed plicatic acid, sensitizer red wood cedar asthma. Bronchial responsiveness, transfer factor, spirometry, precipitating antibodies serum against fungi were measured 164 workers at five sawmills. results from inside sawing area (sawyers, n=59), trimming department (trimmers, n=66), other (sawyer-referents, n=39) compared. Sawyers had higher than...

The objective was to study the postprandial responses of glucose, insulin and triglycerides meal intake at different clock times during night work. Eleven shift working nurses participated. Identical test meals were ingested 19:30, 23:30 03:30, contained 440 kcal/1,860 kJ energy (33 E% fat, 51 carbohydrate, 16 protein). food standardized three days before first meal. Blood samples drawn just thereafter 30, 60, 90, 120, 180 240 minutes. estimated as total area under curve (AUC) significance...

Objectives: To assess the exposure–response relationship between exposure to quartz and fatal silicosis.

Objectives The aim of this study was to investigate myocardial infarction (MI) mortality in relation exposure hand/arm vibration (HAV) and whole body (WBV) as well dust among men employed two Swedish iron-ore mines. Methods This comprised at mines Sweden who had been for least 1 year from 1923 up 1996. causes death were obtained the national cause register 1952 2001. Myocardial by linking personal identification numbers register. Poisson regression used risk estimations on exposure–response...