A5100698969- Syphilis Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Reproductive tract infections research
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Bone and Joint Diseases
- Pelvic and Acetabular Injuries
- Inflammatory Biomarkers in Disease Prognosis
- Spinal Hematomas and Complications
- Lymphoma Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Ginseng Biological Effects and Applications
- Multiple Myeloma Research and Treatments
- Female Genital Mutilation/Cutting Issues
- Musculoskeletal pain and rehabilitation
- Testicular diseases and treatments
- Stress Responses and Cortisol
- Reproductive System and Pregnancy
- Meningioma and schwannoma management
- Management of metastatic bone disease
- Virology and Viral Diseases
- Cardiac Ischemia and Reperfusion
- Spondyloarthritis Studies and Treatments
- Healthcare and Venom Research
- RNA Interference and Gene Delivery
Shenzhen Pingle Orthopedic Hospital
2019-2024
Guangzhou University of Chinese Medicine
2019-2021
Weatherford College
2019-2021
Chinese Medical Center
2021
Creative Commons
2021
Institute of Special Animal and Plant Sciences
2019
Chinese Academy of Agricultural Sciences
2019
Jilin Agricultural University
2019
Southern Medical University
2019
First Hospital of Qinhuangdao
2015-2018
Background: Cytokines in synovial fluid (SF) play a crucial role knee osteoarthritis (KOA). Exosomes are nanovesicles that abundant SF and carry large quantity of signaling molecules. The purpose this study was to evaluate the cytokine profiles SF-derived exosomes try explore its biological function.Methods: Twenty-four KOA patients who were scheduled for their first intra-articular injection or replacement surgery enrolled divided into KL1-2 group KL3-4 according Kellgren Lawrence (KL)...
Osteoporosis is a chronic, progressive disease in which early diagnosis very important. The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte (PLR) have been reported as new predictors inflammatory immune diseases including osteoporosis. No studies relationship between monocyte-to-lymphocyte (MLR) osteoporosis patients.To investigated ability of MLR to predict osteoporosis.Three hundred sixteen patients 111 healthy control subjects were enrolled. Patients' laboratory...
Objective Knee osteoarthritis (KOA) is a chronic inflammatory disease. The monocyte–lymphocyte ratio (MLR) was reported to be non-invasive, cost-effective marker in various systemic diseases, but it has not yet been investigated KOA. This cross-sectional study evaluated the diagnostic value of MLR Methods Two hundred and five KOA patients 120 healthy control subjects were enrolled. Patient data, including age, sex, blood cell counts, erythrocyte sedimentation rate (ESR), C-reactive protein...
This study aimed to determine whether a serological response could predict the normalization of cerebrospinal fluid (CSF) abnormalities at 6 months after treatment in human immunodeficiency virus (HIV)-negative neurosyphilis patients. A total 123 patients were recruited baseline, 58 these undergoing treatment, repeated CSF examinations and tests for syphilis included follow-up study. Before rapid plasma reagin (RPR) titer, Treponema pallidum particle agglutination (TPPA) leukocyte count,...
The inflammasome responses in Treponema pallidum infection have been poorly understood to date. This study aimed investigate the expression of nucleotide-binding leucine-rich receptor protein 3 (NLRP3) development tissue inflammation rabbits infected with T. pallidum. Forty-five were randomly assigned a blank group or an group, and latter was divided into no benzathine penicillin G (BPG) BPG treatment subgroups. Rabbits injected intradermally 0.1 mL 107/mL suspension at 10 marked sites along...
Suppressive effects of ginsenoside Rh₂ (Rh₂), (24R)-pseudo-ginsenoside HQ (R-PHQ), and (24S)-pseudo-ginsenoside (S-PHQ) against lipopolysaccharide (LPS)-induced depression-like behavior were evaluated using the forced swimming test (FST) tail suspension (TST) in mice. Pretreatment with Rh₂, R-PHQ, S-PHQ significantly decreased immobility time FST TST clear dose-dependence, downregulated levels serum tumor necrosis factor-α interleukin-6, upregulated superoxide dismutase activity hippocampus...
SUMMARY This study aimed to comprehensively evaluate factors that influence the likelihood of syphilis infection from risk-taking behaviours and medical conditions. A retrospective case-control was conducted by enrolling 664 inpatients (excluding 11 congenital patients) 800 sex- age-matched controls. Medical histories, clinical data patient interview were collected subjected logistic regression analyses. The prevalence in population 3·9% (675/17 304). By univariate analysis, associated with...
The purpose of the present study was to evaluate prognostic value preoperative coagulation factor levels (including fibrinogen and D-dimer) inflammatory indicators in patients with non-small cell lung cancer (NSCLC). medical records 456 NSCLC who had undergone curative resection were retrospectively analysed. recommended cut-off values for fibrinogen, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte lymphocyte-monocyte determined using receiver operating characteristic curve analyses....
Modified Jiawei Juanbi decoction (MJD) is used for the treatment of early-stage knee osteoarthritis (KOA). Here, modified was employed (KOA) and its mechanisms were assessed via metabonomics network pharmacology. A total 24 male Sprague-Dawley rats randomly allocated into a normal control group, model an MJD group (n = 8 per group). Each rat further equally divided two subgroups investigation either 14 or 28 days. KOA constructed treated with MJD. Effects evaluated based on changes in...
<b><i>Background:</i></b> The differential diagnosis of general paresis (GP) and non-neurosyphilis (NS) dementia is not clearly defined. present study examined the differences in clinical laboratory features GP non-NS dementia. <b><i>Materials Methods:</i></b> We retrospectively 85 patients 196 patients. Data were collected from Zhongshan Hospital between June 2005 2014. <b><i>Results:</i></b> group had a higher...
We developed a new Boson chemiluminescence immunoassay (CIA) and evaluated its application with cross-sectional analyses. Our results indicated that the CIA demonstrated strong discriminatory power in diagnosing syphilis it can be used as first-line screening test for serodiagnosis using European Centre Disease Prevention Control algorithm or confirmatory when combined patient's clinical history.
Background: The diagnostic criteria for active infectious syphilis in the clinic are important matter of controversy and debate. So far, clinicians habitually do use negative results nontreponemal and/or specific antitreponemal IgM as evidences disease-free or infection-free status. Method: We present a case study involving patient who was admitted to Zhongshan Hospital because cerebral infarct. Clinical examination indicated he had history latent with tests. cerebrospinal fluid sample from...
Objective Synovitis is a joint disease that seriously affects patient quality of life, but there are currently no diagnostic markers. The albumin to fibrinogen ratio (AFR) and monocyte lymphocyte (MLR) non-invasive cost-effective markers for various systemic inflammatory diseases. However, these have not yet been investigated synovitis. This cross-sectional study evaluated the predictive ability AFR MLR in patients with non-specific knee Methods One hundred fifty-five synovitis 108 healthy...
Abstract Introduction: Calcification of ligamentum flavum (CLF) is an important cause spinal stenosis and cord compression. CLF does not usually induce immediate quadriparesis. Here we describe a rare case quadriparesis due to large calcified mass containing liquids in the flavum, which was easily confused with gout crystals. Patient concerns: A 74-year-old Asian male felt progressive bilateral arm leg weakness. On fourth day, acute occurred. Diagnosis: Coronal sagittal computerized...
Objective To evaluate the clinical outcome of artificial cervical disc arthroplasty combined with anchoring intervertebral fusion cage (ACIFC) in treatment multilevel herniation. Methods From October 2011 to September 2013, 0.26 patients herniation underwent ACIFC, there were 10 male and 16 female age from 32 60 years (mean 46.8 years). Two segment involved 15 patients, three 11 patients. Neck disability index (NDI) Japanese Orthopaedic Association (JOA) score used neurofunctional...
Objective To study the clinic efficacy of anterior arch resection, atlantoaxial joint release combined with posterior fixation and fusion for odontoid malunion associated irreducible dislocation. Methods From February 2007 to 2012,6 patients (5 males, 1 female) were diagnosed atlanto-axial dislocation. The ages ranged from 36 57 years (average 45.5 years). There traumatic histories spinal injury symptoms in all patients. preoperative Japanese Orthopaedic Association (JOA) score was...