- Marine and fisheries research
- Crustacean biology and ecology
- Coral and Marine Ecosystems Studies
- Fish Ecology and Management Studies
- Genetics and Plant Breeding
- Marine Bivalve and Aquaculture Studies
- Genetic Mapping and Diversity in Plants and Animals
- Crop Yield and Soil Fertility
- Aquaculture Nutrition and Growth
- Child and Adolescent Psychosocial and Emotional Development
- Fish Biology and Ecology Studies
- Wheat and Barley Genetics and Pathology
- Cognitive Abilities and Testing
- Marine animal studies overview
- Coastal and Marine Management
- Genetic and phenotypic traits in livestock
- Marine and coastal plant biology
- Cephalopods and Marine Biology
- Marine Biology and Ecology Research
- Mental Health Research Topics
- Plant Genetic and Mutation Studies
- Fisheries and Aquaculture Studies
- Bioenergy crop production and management
- Identification and Quantification in Food
- Greenhouse Technology and Climate Control
University of Tasmania
2016-2025
Institute for Marine and Antarctic Studies
2016-2025
Washington University in St. Louis
2024
Istituto di Scienze Marine del Consiglio Nazionale delle Ricerche
2024
Cambridge Health Alliance
2015-2021
Harvard University
2019
John Wiley & Sons (United States)
2018
Hudson Institute
2018
Virginia Commonwealth University
1999-2017
University of Central Lancashire
2016
OBJECTIVE: Although previous evidence has suggested that the etiologic role of stressful life events in major depression is reduced recurrent versus first-onset cases, this question deserves reexamination because potential methodological limitations studies. METHOD: Members female-female twin pairs from a population-based registry (N=2,395), who were interviewed four times over period 9 years, formed study group contained 97,515 person-months and 1,380 onsets depression. Discrete-time...
SUMMARY A model is presented for the estimation of genetic effects from diallel cross and related populations a fixed set random-mating varieties with arbitrary gene frequencies at all loci assuming diploid inheritance, two alleles per locus no epistasis. These parameters are defined as functions additive dominance individual loci. An analysis variance appropriate F-tests provided type action involved. Deviations provide test epistasis linkage. Data six maize their crosses analyzed, using...
The authors sought to 1) understand the sources of familial resemblance for religiosity, 2) clarify relationship between religiosity and current psychiatric symptoms, substance use, lifetime disorders, dependence, 3) explore stress-buffering properties religiosity.Data were obtained by personal interview 1,902 twins from female-female pairs in population-based Virginia Twin Registry. Measures included 10 items reflecting a range religious behavior beliefs, scale institutional conservatism...
Background. The development of drug dependence requires prior initiation. What is the relationship between risk factors for initiation and dependence? Methods. Using smoking as a model addiction, we assessed (SI) nicotine (ND) by personal interview in 1898 female twins from population-based Virginia Twin Registry. We developed twin structural equation that estimates correlation liability to SI ND, given SI. Results. liabilities ND were substantially correlated but not identical. Heritable...
Background. Although women are at consistently greater risk for major depression (MD) than men, it is unclear whether sex modifies the aetiological impact of genetic factors on MD. Is heritability MD different in men and women? Do same predispose to two sexes? Methods. We obtained a lifetime history by personal interview occasions from 6672 individual twins 2974 complete twin pairs. Three diagnostic criteria increasing narrowness were employed: DSM-III-R, DSM-III-R plus impairment Washington...
Background. A portion of the genetic risk factors for personality trait neuroticism (N) may also increase major depression (MD). Females have both higher levels N and rates MD than males, suggesting that these traits be more genetically correlated in females. Methods. Structured interviews, including a lifetime assessment by DSM-III-R criteria, were administered to 863 male–male MZ (monozygotic), 649 DZ (dizygotic), 506 female–female MZ, 345 DZ, 1408 opposite-sex twin pairs. was assessed...
Background. While psychiatric epidemiology often focuses on the causal relationship between environmental adversity and individual (e.g. environment to person), individuals probably make important contributions quality of their environments (person environment). Method. In a population based sample >7000 male female adult twins, we examined personality trait neuroticism (N) occurrence stressful life events (SLEs) interpersonal relationships (IPR). We compared magnitude prediction twin 1's...
Background Little is known about the pattern of genetic and environmental influences on symptoms anxiety depression (SxAnxDep) from childhood to early adulthood. Method Parental- self-reported levels SxAnxDep were assessed at ages 8–9, 13–14, 16–17 19–20 years in 2508 twins Swedish Twin Study Child Adolescent Development (TCHAD). Analysis conducted using Mx program included by parental self-report. Results The best-fit model revealed one risk factor for acting 19–20, new sets factors ‘coming...
The nature of the relationship between depressive vulnerability (DV) and acute adversity in etiology major depression (MD) remains poorly understood.Stressful life events (SLEs) MD onsets last year were assessed at four waves cohort 1 (females) two 2 (males females) from Virginia Adult Twin Study. Structural equation modeling was conducted Mplus.In 1, DV strongly indexed by episodes over (paths +0.72 to 0.79) predicted SLEs month their occurrence (+0.31 0.36). Wave-specific associated both...
Alcohol consumption is influenced by specific genetic risk factors for alcohol use disorders (AUDs), non-specific externalizing behaviors and various environmental experiences. We have limited knowledge of how these inter-relate through development.Retrospective assessments in 1796 adult male twins using a life history calendar key exposures from early adolescence to mid-adulthood. Analysis linear mixed models.The importance on maximal rose rapidly mid-adolescence, peaked at ages 15-17 years...
A model is proposed to characterize the means of a fixed set varieties, variety crosses and other entries obtained from these varieties crosses. The can be pure-line inbred lines with any degree inbreeding as well open-pollinated or synthetic long are in Hardy-Weinberg equilibrium. Parameters defined for additive, dominance additive by epistatic effects assuming diploid inheritance. Tests available analysis variance deviations due higher order epistasis (and/or linkage epistasis). If...
Background. Whereas a number of studies have suggested that parental loss is associated with increased risk for major depression (MD), much less known about possible gender differences, diagnostic specificity and the time course impact loss. Method. First-onsets MD alcohol dependence (AD) were assessed at personal interviews in 5070 twins from same-sex (SS) 2118 opposite-sex (OS) twin pairs ascertained population-based registry. Cox Proportional Hazard (PH) Non-Proportional (NPH) models,...
Background Designed as state measures to monitor treatment response, symptoms of anxiety and depression (SxAnxDep) also have trait-like characteristics. No comprehensive etiologic model for SxAnxDep has illuminated the inter-relationship between their state- characteristics, while including key predictor variables. Method In a prospective three-wave study 2395 female twins from Virginia Adult Twin Study Psychiatric Substance Use Disorders (VATSPSUD), we examined, using structural equation...
Interview with Dr. Caleb Gardner on the limitations of an increasing focus biologic knowledge in psychiatry. (11:22)Download In psychiatry, checklists symptoms now take place thoughtful diagnosis, and trial-and-error "medication management" dominates practice. We face stark treatments, while finding less time to work patients difficult problems.
The net movement of individuals from marine reserves (also known as no-take protected areas) to the remaining fishing grounds is spillover and frequently used promote fishers on that it will benefit fisheries. Here we consider how mismanaged a fishery must be before reserve able provide for fishery. For our model fishery, density species being harvested becomes higher in than fished area but reduction yield was such effect closure negative, except when mismanaged. extent which effort had...
N an earlier paper (CALDECOTT et al. 1952) it was demonstrated that there I w'ere pronounced differences in the biological effect of X-rays and thermal neutrons on dormant seeds barley.The present investigation undertaken effort to elucidate these attempt explain them purely physical assumptions.The reader is referred reviews by LEA (1947) SPARROW RUBIN
Differential use of each hemisphere the brain for specific tasks is a widespread phenomenon that appears to have arisen in early history tetrapod lineage. Despite high degree conformity development lateralization among tetrapods, some variation exists. The mechanisms underlying this remain largely unresolved. We exposed fish from regions and low predation pressure series visual experiences, including viewing an empty compartment, novel object live predator. Fish region differed their...
Recent studies among males have reported a genotype-environment interaction (GxE) in which low-activity alleles at the monoamine oxidase A (MAOA) locus conferred greater sensitivity to effects of childhood adversity on risk for conduct disorder (CD). So far, few females controlled gene-environment correlation or used heterozygous this X-linked gene.Logistic regression analysis sample 721 ages 8-17 years from longitudinal Virginia Twin Study Adolescent Behavioral Development (VTSABD) assessed...