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Antonia Felzen

ORCID: 0000-0003-0326-9622
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A5040722876
Research Areas
  • Pediatric Hepatobiliary Diseases and Treatments
  • Drug Transport and Resistance Mechanisms
  • Liver Diseases and Immunity
  • Recycling and Waste Management Techniques
  • Biomedical Research and Pathophysiology
  • Digestive system and related health
  • Genetics and Neurodevelopmental Disorders
  • Belt Conveyor Systems Engineering
  • Gastroesophageal reflux and treatments

University Medical Center Groningen
 2021-2023

University of Groningen
 2021-2023

University of Ottawa
 2022

Children's Hospital of Eastern Ontario
 2022

 EASL Clinical Practice Guidelines on genetic cholestatic liver diseases
OPENALEX - Publications 
Henkjan J. Verkade Antonia Felzen Verena Keitel Richard Thompson Emmanuel Gonzalès and 3 more Pavel Strnad Binita M. Kamath Saskia W. C. van Mil

10.1016/j.jhep.2024.04.006 article EN Journal of Hepatology 2024-06-08
 Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency
OPENALEX - Publications 
Antonia Felzen Daan van Wessel Emmanuel Gonzalès Richard J. Thompson Irena Jankowska and 67 more Benjamin L. Shneider Étienne Sokal Tassos Grammatikopoulos Agustina Kadaristiana Emmanuel Jacquemin Anne Spraul Patryk Lipiński Piotr Czubkowski Nathalie Rock Mohammad Shagrani Dieter C. Bröering Emanuele Nicastro Déirdre Kelly Gabriella Nebbia Henrik Arnell Björn Fischler Jan B.F. Hulscher Daniele Serranti Çiğdem Arıkan Esra Polat Dominique Debray Florence Lacaille Cristina Gonçalves Loreto Hierro Gema Muñoz Bartolo Yael Mozer‐Glassberg Amer Azaz Jernej Brecelj Antal Dezsöfi Pier Luigi Calvo Enke Grabhorn Steffen Hartleif Wendy J. van der Woerd Binita M. Kamath Jian‐She Wang Liting Li Özlem Durmaz Nanda Kerkar Marianne Hørby Jørgensen Ryan T. Fischer Carolina Jiménez‐Rivera Seema Alam Mara Cananzi Noémie Laverdure Cristina Targa Ferreira Felipe Ordoñez Guerrero Heng Wang Valerie Sency Kyung Mo Kim Huey‐Ling Chen Elisa de Carvalho Alexandre Fabre Jesús Quintero Aglaia Zellos Estella M. Alonso Ronald J. Sokol Frederick J. Suchy Kathleen M. Loomes Patrick McKiernan Philip Rosenthal Yumirle P. Turmelle Simon Horslen Kathleen B. Schwarz Jorge A. Bezerra Kasper Wang Bettina E. Hansen Henkjan J. Verkade

Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in

10.1016/j.jhepr.2022.100626 article EN cc-by JHEP Reports 2022-11-16
 Analysis of long-term treatment effects of odevixibat on clinical outcomes in children with progressive familial intrahepatic cholestasis in odevixibat clinical studies vs external controls from the NAPPED database
OPENALEX - Publications 
Bettina E. Hansen Velichka Valcheva Qifeng Yu Daan van Wessel Richard Thompson and 49 more Emmanuel Gonzalès Irena Jankowska Étienne Sokal Tassos Grammatikopoulos Agustina Kadaristiana Emmanuel Jacquemin Anne Spraul Patryk Lipiński Piotr Czubkowski Nathalie Rock Mohammad Shagrani Kishwer Kumar Fowzan S. Alkuraya Meddirevula Sateesh Dieter C. Bröering Emanuele Nicastro Déirdre Kelly Gabriella Nebbia Henrik Arnell Björn Fischler Daniele Serranti Çiğdem Arıkan Esra Polat Dominique Debray Florence Lacaille Cristina Gonçalves Loreto Hierro Gema Muñoz Bartolo Yael Mozer‐Glassberg Amer Azaz Jernej Brecelj Antal Dezsöfi Pier Luigi Calvo Enke Grabhorn Ekkehard Sturm Wendy L. van der Woerd Binita M. Kamath Jian‐She Wang Liting Li Özlem Durmaz Zerrin Önal Antonia Felzen Mark Nomden Jaak Sõnajalg Philip Stein Quanhong Ni Christine Clemson Jan P. Mattsson Henkjan J. Verkade

10.1016/s0168-8278(23)03022-2 article EN Journal of Hepatology 2023-06-01
 P1 Analysis of long-term treatment effects of odevixibat on clinical outcomes in children with progressive familial intrahepatic cholestasis in odevixibat clinical studies vs external controls from the NAPPED database
OPENALEX - Publications 
Bettina E. Hansen Velichka Valcheva Qifeng Yu Daan BE van Wessel Richard J. Thompson and 49 more Emmanuel Gonzalès Irena Jankowska Étienne Sokal Tassos Grammatikopoulos Agustina Kadaristiana Emmanuel Jacquemin Anne Spraul Patryk Lipi nacute ski Piotr Czubkowski Nathalie Rock Mohammad Shagrani Kishwer Kumar Fowzan S. Alkuraya Meddirevula Sateesh Dieter Broering Emanuele Nicastro Déirdre Kelly Gabriella Nebbia Henrik Arnell Björn Fischler Daniele Serranti Çiğdem Arıkan Esra Polat Dominique Debray Florence Lacaille Cristina Gonçalves Loreto Hierro Gema Muñoz Bartolo Yael Mozer‐Glassberg Amer Azaz Jernej Brecelj Antal Dezs odblac fi Pier Luigi Calvo Enke Grabhorn Ekkehard Sturm Wendy L. van der Woerd Binita M. Kamath Jian‐She Wang Liting Li Özlem Durmaz Zerrin Önal Antonia Felzen Mark Nomden Jaak Sõnajalg Philip Stein Quanhong Ni Christine Clemson Jan P. Mattsson Henkjan J. Verkade

<h3>Background</h3> Progressive familial intrahepatic cholestasis (PFIC) is a group of rare cholestatic liver diseases characterised by intractable pruritus, elevated serum bile acids (sBAs), and progressive damage. NAPPED (NAtural course Prognosis PFIC Effect biliary Diversion) large retrospective database investigating the natural history PFIC. Odevixibat, an ileal acid transporter inhibitor, reduced sBAs pruritus in patients with phase 3 PEDFIC 1 2 studies. We compared clinical outcomes...

10.1136/gutjnl-2023-basl.17 article EN Poster presentations 2023-09-01
 The phenotype of compound heterozygous BSEP deficiency patients is determined by the combined residual function of the two ABCB11 mutations: results from the NAPPED consortium
OPENALEX - Publications 
Antonia Felzen Daan van Wessel Richard F. Thompson Emmanuel Gonzalès Irena Jankowska and 53 more Étienne Sokal Tassos Grammatikopoulos Agustina Kadaristiana Emmanuel Jacquemin Anne Spraul Patryk Lipiński Piotr Czubkowski Nathalie Rock Mohammad Shagrani Dieter C. Bröering Talal Algoufi Nejat Mazhar Emanuele Nicastro Déirdre Kelly Gabriella Nebbia Henrik Arnell Björn Fischler JBF Hulscher Daniele Serranti Çiğdem Arıkan Esra Polat Dominique Debray Florence Lacaille Cristina Gonçalves Loreto Hierro Gema Muñoz Bartolo Yael Mozer Glassberg Amer Azaz Jernej Brecelj Antal Dezsöfi Pier Luigi Calvo Enke Grabhorn Ekkehard Sturm Wendy van der Woerd Binita M. Kamath Jian‐She Wang Liting Li Özlem Durmaz Nanda Kerkar Marianne Hørby Jørgensen Ryan Fischer Carolina Jiménez‐Rivera Seema Alam Mara Cananzi Mathias Ruiz Cristina Targa Felipe Ordoñez Ferrero Heng Wang Kyung Mo Kim Huey‐Ling Chen Elisa de Carvalho Bettina E. Hansen Henkjan J. Verkade

10.1016/s0168-8278(20)31546-4 article EN Journal of Hepatology 2020-08-01
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