Abstract Objectives To evaluate clinical, radiographic, microbiologic, and biomechanical parameters related to bone remodeling around implants with external hexagon (EH) Morse‐taper (MT) connections. Materials Methods Twelve totally edentulous patients received four custom‐made in the interforaminal region of mandible. Two those had same macroscopic design, but different prosthetic All an immediate implant‐supported prosthesis. Clinical (periimplant probing pocket depth (PPD), modified...

ABSTRACT Although, intracellular signaling pathways are proposed to predict the quality of cell‐surface relationship, this study addressed pre‐osteoblast behavior in response nano hydroxyapatite (HA)‐blasted titanium (Ti) surface by exploring critical and morphological change. Physicochemical properties were evaluated atomic force microscopy (AFM) wettability considering water contact angle three differently texturized Ti surfaces: Machined (Mac), Dual acid‐etching (DAE),...

To evaluate the accuracy of static computer-assisted implant surgery (sCAIS) for tooth-supported free-end dental implantation with aid/and without aid fixation pins to secure surgical template through comparison between planned, 3D printed guide position and placement position.Thirty-two duplicated maxillary resin models were used in present vitro study. Digital planning was performed fabrication a that allowed on distal extension edentulous site model (maxillary left side). A first optical...

Objective This in vivo study, aimed to biomechanically, histomorphometrically and histologically evaluate an implant surface coated with nanostructured hydroxyapatite using the wet chemical process (biomimetic deposition of calcium phosphate coating) when compared a dual acid-etching surface. Material methods Ten sheep (2–4 years old) received 20 implants, 10 coating (HAnano), (DAA). The surfaces were characterized scanning electron microscopy energy dispersive spectroscopy; insertion torque...

Abstract It is important to understand the cellular and molecular events that occur at cell–material interface of implants used for bone repair. The mechanisms involved in initial stages osteoblast interactions with surface implant material must be decisive cell fating surrounding them. In order address this issue, we decided investigate if conditioned medium dental was able modulate murine pre‐osteoblast metabolism. First, determined concentration titanium (Ti)‐containing found it 2‐fold...

Abstract Although osseointegration and clinical success of titanium (Ti)-implanted materials depend on neovascularization in the reactional peri-implant tissue, very little has been achieved considering Ti-molecules release behavior endothelial cells. To address this issue, we challenged cells (HUVECs) with Ti-enriched medium obtained from two types commercial surfaces [presenting or not dual-acid etching (DAE)] up to 72 h allow molecular machinery analysis. Our data show that provokes...

Abstract This study evaluates the effects of a green tea (Camellia sinensis) and hyaluronic acid gel on fibroblast activity alveolar bone repair following third molar extractions. By examining gene expression related to cell survival, proliferation, angiogenesis, bridges in vitro findings with clinical outcomes split-mouth randomized trial. Human fibroblasts were exposed treatment gel, analysing through RT-qPCR. Twenty participants undergoing bilateral extractions received test one side...

A utilização de dispositivos transitórios ancoragem, como coadjuvante no tratamento ortodôntico, tem demonstrado, nos últimos anos, alta versatilidade aplicação clínica, principalmente que tange o uso dos miniimplantes. Estes aparatos surgem alternativa para os casos em a ancoragem se torna fator crítico sucesso do ortodôntico. Neste artigo, buscamos uma abordagem ampla tema, incluindo: locais instalação, procedimentos cirúrgicos, indicações, cuidados com higiene e complicações mais freqüentes na

Abstract Primary implant stability is a prerequisite for successful osseointegration. The osseodensification technique (OD) non-subtractive drilling that preserves the bone tissue, increases osteotomy wall density, and improves primary stability. This study aimed to investigate hypothesis OD, through wider osteotomy, produces healing chambers (HCs) at implant-bone interface without impacting low-density Twenty implants (3.5 × 10 mm) with nanohydroxyapatite (nHA) surface were inserted in...

Hydroxyapatite used as a coating for titanium dental implants reduces the time required osseointegration. Platelet-rich fibrin (L-PRF) releases growth factors and cytokines, enhancing tissue healing bone regeneration. This study aimed to evaluate histologically, histomorphometrically, by microcomputed tomography an implant surface coated with nanostructured hydroxyapatite (HAnano), in comparison double acid-etched (DAA) surface, both without peri-implant grafting L-PRF, installed...

Nanosized crystalline hydroxyapatite coating (HAnano®) accelerates the osteointegration of dental implants which is hypothesized to drive angiogenesis. In order test this hypothesis, we have subjected shear-stressed human umbilical vein endothelial cells (HUVECs) a HAnano®-enriched medium, as well surface presenting dual acid etching (DAE) control. To note, titanium were coated with 10 nm in diameter HA particles using Promimic HAnano method. Our data reveals that HAnano® modulates higher...

The success of dental implants depends on osseointegration can be compromised by well-known related adverse biological processes, such as infection and diabetes. Previously, nanohydroxyapatite-coated titanium surfaces (nHA_DAE) have been shown to contain properties that promote osteogenesis enhancing osteoblast differentiation. In addition, it was hypothesized drive angiogenesis in high-glucose microenvironments, mimicking diabetes mellitus (DM). On the other hand, null hypothesis would...

The aim of the present study was to investigate relationship between specific polymorphisms interleukin-1 gene cluster and early failure osseointegrated implants.The subject population composed by a test group comprising 28 non-smoking patients (mean age 52.7) that had suffered one or more implant failures control consisting 34 individuals 43.3) with healthy implants. Genomic DNA from buccal mucosa amplified polymerase chain reaction (PCR), followed restriction fragment length polymorphism...

Background: It is not yet well understood to what extent different implant–abutment mismatch sizes and connection types may influence the peri‐implant biomechanical environment of implants in clinical situations. Methods: Computed tomography–based finite element models comprising a maxillary central incisor socket 4.5 × 13 mm outer‐diameter with external internal hex were constructed. The abutments designed diameters 3.5 (platform switching [PS] 1 diametral [PS − 1]), 4.0 (PS 0.5 0.5]),...

The success rates of dental implants in low-density bone have been reported as a challenge, especially for early or immediate loading the maxilla posterior area. Nanoscale architecture affects roughness, surface area, energy implant and can enhance osseointegration. This study aimed to evaluate implant-surface topography biomechanical, histomorphometric, histological responses new nanostructured hydroxyapatite placed iliac crest sheep.Ten female sheep (2-4 years) received 30 (n=10/group):...

Implant installation with conventional drilling can create buccal bone defects in areas of limited ridge thickness. osseodensification may aid preventing these situations. This vitro pilot study evaluated the impact on increase alveolar thickness and prevention peri-implant defects.Ten fresh pig mandibles were selected for use an experimental randomized split mouth study. Two site-preparation protocols used: cutting burs (CTL, n = 10) Densah® (OD, 10). After implant bed preparation, 20...