A5091255997- Neuroscience and Neural Engineering
- Conducting polymers and applications
- Advanced Sensor and Energy Harvesting Materials
- Analytical Chemistry and Sensors
- Advanced Memory and Neural Computing
- Muscle activation and electromyography studies
- EEG and Brain-Computer Interfaces
- 3D Printing in Biomedical Research
- Organic Electronics and Photovoltaics
- Neural dynamics and brain function
- Molecular Communication and Nanonetworks
- Photoreceptor and optogenetics research
- Electrochemical sensors and biosensors
- Wireless Body Area Networks
- Tactile and Sensory Interactions
- Advanced Chemical Sensor Technologies
- Polymer Surface Interaction Studies
- Nanofabrication and Lithography Techniques
- Complementary and Alternative Medicine Studies
- Diatoms and Algae Research
- Gas Sensing Nanomaterials and Sensors
- Interactive and Immersive Displays
- Block Copolymer Self-Assembly
- Pharmacology and Obesity Treatment
- Teaching and Learning Programming
Istituto Universitario di Studi Superiori di Pavia
2023-2025
University of Cagliari
2013-2023
Fondazione Bruno Kessler
2018-2019
Kessler Foundation
2018
University of Genoa
2013-2016
Associazione Istituzione Libera Università Nuorese
2014
Electrolyte-gated transistors (EGTs), capable of transducing biological and biochemical inputs into amplified electronic signals stably operating in aqueous environments, have emerged as fundamental building blocks bioelectronics. In this Primer, the different EGT architectures are described with mechanisms underpinning their functional operation, providing insight key experiments including necessary data analysis validation. Several organic inorganic materials used structures fabrication...
Abstract In this study, a novel approach to the fabrication of multimodal temperature and force sensor on ultrathin, conformable flexible substrates is presented. This process involves coupling charge-modulated organic field-effect transistor (OCMFET) with pyro/piezoelectric element, namely commercial film poly-vinylene difluoride (PVDF). The proposed device able respond both pressure stimuli variations, demonstrating feasibility for development low-cost, highly sensitive sensors. overall...
Abstract In the last four decades, substantial advances have been done in understanding of electrical behavior excitable cells. From introduction early 70's Ion Sensitive Field Effect Transistor (ISFET), a lot effort has put development more and performing transistor-based devices to reliably interface electrogenic cells such as, for example, cardiac myocytes neurons. However, depending on type application, electronic used this aim face several problems like intrinsic rigidity materials...
In recent years, the variety of textile electrodes developed for electrophysiological signal detection has increased rapidly. Among applications that could benefit from this advancement, those based on surface electromyography (sEMG) are particularly relevant in rehabilitation, training, and muscle function assessment. work, we validate performance polymer-based screen-printed sEMG detection. We obtained these by depositing poly-3,4-ethylenedioxythiophene doped with poly(styrene sulfonate)...
In an increasingly interconnected world, where electronic devices permeate every aspect of our lives, wearable systems aimed at monitoring physiological signals are rapidly taking over the sport and fitness domain, as well biomedical fields such rehabilitation prosthetics. With intent providing a novel approach to field, in this paper we discuss development system for acquisition EEG based on portable, low-power custom PCB specifically designed be used combination with non-conventional...
<title>Abstract</title> In this study, we present the development of an advanced multivariable sensing platform that combines a flexible extended-gate organic thin-film transistor (ExG-OTFT) with surface plasmon resonance (SPR) readout its surface. This device architecture overcomes limitations prior combined SPR and field-effect (FET)-based systems, thanks to spatial separation from body, implementation pseudo-reference electrode, which significantly improves system reliability. We...
In this study, we present the development of an advanced multivariable sensing platform that combines a flexible extended-gate organic thin-film transistor (ExG-OTFT) with surface plasmon resonance (SPR) readout its surface. This device architecture overcomes limitations prior combined SPR and field-effect (FET)-based systems, thanks to spatial separation from body, implementation pseudo-reference electrode, which significantly improves system reliability. We demonstrate potential solution...
The ability of field effect transistors (FETs) to detect charge variations on the gate may be exploited for realizing chemo- and bio-sensors. In this paper, we focus our attention a particular kind device, named organic modulated FETs, whose features can optimized detection in liquid solutions. results measurement different bio-related effects are shown. particular, DNA hybridization pH media proposed. Finally, preliminary considerations about applicability these devices electrical activity...
Objective. In this paper, we report on the development of an easy-to-fabricate three-dimensional Micro-Electrode Array (3D-MEA) specifically designed for brain-on-a-dish applications. Approach. The proposed device consists pillar-shaped gold microelectrodes realized by electroplating directly top a standard MEA, making approach highly versatile and convenient batch fabrication. Moreover, with simple technique, it is possible to obtain electrodes height more than 100 µm onto different kind...
A breathable tattoo electrode for bio-potential recording based on a Parylene C nanofilm is presented in this study. The proposed approach allows the fabrication of micro-perforated epidermal submicrometer-thick electrodes that conjugate unobtrusiveness nanofilms and very important feature breathability. were fully validated electrocardiography (ECG) measurements showing performance comparable to conventional disposable gelled Ag/AgCl electrodes, with no visible negative effect skin even...
In this manuscript, we report on a novel architecture for the fabrication of highly sensitive multimodal tactile transducers, simultaneous detection temperature and force. Such devices are based flexible Organic Charge Modulated Field Effect Transistor (OCMFET) coupled with pyro/piezoelectric element, namely commercial film poly-vinylene difluoride (PVDF). The reduction channel length, obtained by employing low-resolution vertical architecture, allowed to maximize ratio between sensing area...
Objective. Wearable devices have created new opportunities in healthcare and sport sciences by unobtrusively monitoring physiological signals. Textile polymer-based electrodes proved to be effective detecting electrophysiological potentials but suffer mechanical fragility low stretch resistance. The goal of this research is develop validate dynamic conditions cost-effective easily manufacturable characterized adequate robustness signal quality. Methods. We here propose an optimized screen...
The ability to modify substrates with thin polymer films allows for the tailoring of surface properties, and through combination patterning finds use in a large variety applications such as electronics lab-on-chip devices. Although many techniques can be used afford polymer-modified surfaces surface-initiated polymerization or layer-by-layer methodologies, their stability wide range environments well target specific chemistry are critical factors enable successful application. In this paper,...
Body channel communication (BCC) is a technique for data transmission exploiting the human body as channel. Even though it was pioneered about 25 years ago, identification of good electrical model behind its functioning still an open research question. The proposed distributed can then serve supporting tool design, allowing to enhance performances any BCC system. A novel finite periodic line developed describe medium. According this model, first time, parasitic capacitance between...
Monitoring cell metabolism in vitro is considered a relevant methodology several scientific fields ranging from fundamental biology research to neuro-toxicology. In the last 20 years, neuro-pharmacological and neuro-toxicological approaches have been developed, with intent of addressing increasing demand for real-time, non-invasive systems capable continuously reliably monitoring cellular activity. this paper, an Organic Charge Modulated Field Effect Transistor-based device proposed as...
Understanding how the brain process and store information is one of most important quest in modern science. To this aim, vitro neuronal models still represent a relevant approach, continuous improvement in-vitro methodologies for monitoring neurons electrical activity fact an requirement. Moreover, with advent novel approaches development 3D models, assessing neural connectivity such complex cellular structures has lately become research objective that requires innovative platforms...
Interfacing ultrathin functional films for epidermal applications with external recording instruments or readout electronics still represents one of the biggest challenges in field tattoo electronics. With aim providing a convenient solution to this ever-present limitation, work we propose an innovative free-standing electrode made composite thin film based on combination conductive polymer PEDOT:PSS and ferrimagnetic powder. The proposed can be directly transferred onto skin is structured...
The past decade has been characterized by an impressive surge of wearable electronics devices for biopotential recording applications. Due to its important potential impact, the EEG (electroencephalography) signals recently raised considerable interest within this new paradigm human-electronics interfacing. Ideally, application would require minimally-invasive acquisition and highly comfortable electrodes, two complex features that have not completely resolved. main problems concerning...
In this work, novel ultrathin and unperceivable Parylene C electrodes (conventionally indicated as 'tattoo electrodes') for ECG detection were comparatively assessed against off-the-shelf gelled Ag/AgCl ones. To aim, six 60s-long single-lead signals recorded from three volunteers. Signals tattoo simultaneously acquired at 2048 Hz using the TMSi Porti7 system. Although suffered slightly higher baseline wandering artifacts (1 ±1 m V) than ones (0.08±0.04 mV), they both achieved high similar...
Abstract In some countries, it is illegal to drive with any detectable amount of alcohol in blood; others, the legal limit 0.5 g/L or lower. Recently, defendants charged driving under influence and have claimed that positive breath test results were due ingestion homeopathic mother tinctures. These preparations are obtained by maceration, digestion, infusion, decoction herbal material hydroalcoholic solvent. A series tests conducted evaluate alcoholic content three tinctures their ability...
In vitro electrogenic cells monitoring is an important objective in several scientific and technological fields, such as electrophysiology, pharmacology brain machine interfaces, can represent interesting opportunity other translational medicine applications. One of the key aspects cellular cultures complexity their behavior, due to different kinds bio-related signals, both chemical electrical, that characterize these systems. order fully understand exploit this extraordinary complexity,...