A5029514482- Neuroscience and Music Perception
- Hearing Loss and Rehabilitation
- Neural dynamics and brain function
- Blind Source Separation Techniques
- Neonatal and fetal brain pathology
- Genetic Neurodegenerative Diseases
- Heart Rate Variability and Autonomic Control
- Language Development and Disorders
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Vestibular and auditory disorders
- Mitochondrial Function and Pathology
- Neurological disorders and treatments
- Phonocardiography and Auscultation Techniques
- Infant Health and Development
- Reading and Literacy Development
- Non-Invasive Vital Sign Monitoring
- Multisensory perception and integration
- Neural Networks and Applications
- Advanced Neuroimaging Techniques and Applications
- Autoimmune and Inflammatory Disorders Research
- Fetal and Pediatric Neurological Disorders
- Sleep and Wakefulness Research
- Visual perception and processing mechanisms
- Botulinum Toxin and Related Neurological Disorders
University of Duisburg-Essen
2018-2024
Essen University Hospital
2019-2022
University of Tübingen
2009-2020
St. Elisabeth-Hospital Bochum
2013-2014
Bernstein Center for Computational Neuroscience Tübingen
2010-2012
University of Münster
2001-2009
Universitätsklinikum Tübingen
2009
University of Arkansas for Medical Sciences
2006
University Hospital Münster
2003
Bulgarian Academy of Sciences
1999
Different types of generation mechanisms 40-Hz auditory steady-state response (ASSR) were investigated using diotic and dichotic stimulation with 500- 540-Hz pure tones 1.0-s duration 2.0-s stimulus onset asynchrony. When the sum both was presented to ears simultaneously, they interacted at cochlear level resulted in perception a beat termed "peripheral beat." Dichotic presentation 500-Hz tone one ear other as effect central interaction, most likely superior olivary nuclei "central ASSR...
Fetal behavioral states are defined by fetal movement and heart rate variability (HRV). At 32 weeks of gestational age (GA) the distinction four represented combinations quiet or active sleep awakeness is possible. Prior to weeks, only periods activity quiesence can be distinguished. The increasing synchronization HRV reflects development autonomic nervous system (ANS) control. magnetocardiography (fMCG) detects at high temporal resolution, enabling calculation parameters. This study...
The investigation of functional hemispheric asymmetries regarding auditory processing in the human brain still remains a challenge. Classical lesion and recent neuroimaging studies indicated that speech is dominantly processed left hemisphere, whereas music right. However, demonstrated were not limited to highly cognitive sound signals like but rather originated from basic neural elementary features, is, spectral temporal acoustic features. Here, contrast previous studies, we used carefully...
Numerosity discrimination has been demonstrated in newborns, but not fetuses. Fetal magnetoencephalography allows non-invasive investigation of neural responses neonates and During an oddball paradigm with auditory sequences differing numerosity, evoked were recorded mismatch quantified as indicator for discrimination. Thirty pregnant women healthy fetuses (last trimester) 30 term participated. Fourteen adults included a control group. Based on measurements eligible analysis, all adults,...
Objective Multiple amplitude modulation (AM) of a tone results in time series with complex structure envelope fluctuations. In this study the cortical responses elicited by such an auditory stimulus were investigated. It was hypothesized that cortex responds simultaneously different patterns activity corresponding to rhythm periodical The relations these response either steady-state (SSR) 40 Hz range or transient slow evoked Design Auditory magnetic fields recorded from left temporal nine...
Due to auditory experience, musicians have better expertise than non-musicians. An increased neocortical activity during oddball stimulation was observed in different studies for and non-musicians after discrimination training. This suggests a modification of synaptic strength among simultaneously active neurons due the We used amplitude-modulated tones (AM) presented an sequence manipulated their carrier or modulation frequencies. investigated order see if behavioral training could modify...
Auditory change detection is crucial for the development of auditory system and a prerequisite language development. In neonates, stimuli with broad spectral width like white noise (WN) elicit highest response compared to pure tone combined stimuli. current study we addressed first time question how fetuses react "WN" stimulation. Twenty-five (M age = 34.59 weeks GA, SD ± 2.35) 28 healthy neonates infants 37.18 days, 15.52) were tested paradigm, wherein 500 Hz tones, 750 WN segments randomly...
Abstract Cerebellar degeneration progressively impairs motor function. Recent research showed that cerebellar patients can improve performance with practice, but the optimal feedback type (visual, proprioceptive, verbal) for such learning and underlying neuroplastic changes are unknown. Here, ( N = 40) age‐ sex‐matched healthy controls practiced single‐joint, goal‐directed forearm movements 5 days. improved during visuomotor a training focusing on either proprioceptive feedback, or explicit...
NEW & NOTEWORTHY: Neurodegeneration of the cerebellum progresses over years and primarily affects cerebellar cortex. It leads to a progressive loss control coordination movement. We here show that neurodegenerative process not only cells in cortex but also induces neurostructural changes form increased gray matter efferent targets cortex, namely, output nuclei, SMA, premotor
Abstract Background The aim of the present study was to identify a specific neuronal correlate underlying pre-attentive auditory stream segregation subsequent sound patterns alternating in spectral or temporal cues. Fifteen participants with normal hearing were presented series’ two consecutive ABA tone-triplet sequences, initial triplets being Adaptation sequence and Test sequence. In first experiment, frequency separation (delta-f) between A B tones sequences varied by 2, 4 10 semitones....
Background Auditory steady-state responses (ASSRs) are ongoing evoked brain to continuous auditory stimuli that play a role for processing of complex sounds and speech perception. Transient event-related (AERRs) have previously been recorded using fetal magnetoencephalography (fMEG) but involve different neurological pathways. Previous studies in children adults demonstrated the cortical components ASSR significantly affected by state consciousness maturational changes neonates young...
Objective: The objective of this report is to detect cardiac time intervals (CTIs) in fetuses exposed SSA/Ro-SSB/La antibodies relation gestational age (GA) and fetal weight compared them with a control cohort. Methods: Fetal magnetocardiography (fMCG) recordings were conducted on biomagnetic device dedicated obstetrical measurement starting the second trimester. 87 healthy normal gestation (control group) 11 maternal (study group). Results: fCTIs analyzed at 17 weeks GA. Atrial ventricular...